Therapeutic Embolization for Hemorrhage from Locally Recurrent Cancer of the Breast

Radiology ◽  
1978 ◽  
Vol 129 (2) ◽  
pp. 307-310 ◽  
Author(s):  
Donald P. Harrington ◽  
Klemens H. Barth ◽  
Robinson R. Baker ◽  
Bradley T. Truax ◽  
Martin D. Abeloff ◽  
...  
Keyword(s):  
Therapeutic Embolization ◽  
Recurrent Cancer ◽  
Locally Recurrent

scholarly journals Cutaneous field cancerization: clinical, histopathological and therapeutic aspects

2013 ◽  
Vol 88 (5) ◽  
pp. 775-786 ◽  
Author(s):  
Luis Antonio Ribeiro Torezan ◽  
Cyro Festa-Neto
Keyword(s):  
Primary Tumor ◽  
Field Cancerization ◽  
Second Primary ◽  
Time Interval ◽  
Primary Tumors ◽  
Recurrent Cancer ◽  
Epithelial Cancers ◽  
Organ Systems ◽  
Clinical Consequences ◽  
Locally Recurrent

The concept of "field cancerization" was first introduced by Slaughter in 1953 when studying the presence of histologically abnormal tissue surrounding oral squamous cell carcinoma. It was proposed to explain the development of multiple primary tumors and locally recurrent cancer. Organ systems in which field cancerization has been described since then are: head and neck (oral cavity, oropharynx, and larynx), lung, vulva, esophagus, cervix, breast, skin, colon, and bladder. Recent molecular studies support the carcinogenesis model in which the development of a field with genetically altered cells plays a central role. An important clinical implication is that fields often remain after the surgery for the primary tumor and may lead to new cancers, designated presently as "a second primary tumor" or "local recurrence," depending on the exact site and time interval. In conclusion, the development of an expanding pre-neoplastic field appears to be a critical step in epithelial carcinogenesis with important clinical consequences. Diagnosis and treatment of epithelial cancers should not only be focused on the tumor but also on the field from which it developed. The most important etiopathogenetic, clinical, histopathological and therapeutic aspects of field cancerization are reviewed in this article.

scholarly journals Total Pelvic Exenteration for Gynecologic Malignancies

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Elisabeth J. Diver ◽  
J. Alejandro Rauh-Hain ◽  
Marcela G. del Carmen
Keyword(s):  
Pelvic Exenteration ◽  
Gynecologic Oncology ◽  
Evaluation Process ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
Total Pelvic Exenteration ◽  
Gynecologic Malignancies ◽  
En Bloc ◽  
Recurrent Cancer ◽  
Locally Recurrent

Total pelvic exenteration (PE) is a radical operation, involving en bloc resection of pelvic organs, including reproductive structures, bladder, and rectosigmoid. In gynecologic oncology, it is most commonly indicated for the treatment of advanced primary or locally recurrent cancer. Careful patient selection and counseling are of paramount importance when considering someone for PE. Part of the evaluation process includes comprehensive assessment to exclude unresectable or metastatic disease. PE can be curative for carefully selected patients with gynecologic cancers. Major complications can be seen in as many as 50% of patients undergoing PE, underscoring the need to carefully discuss risks and benefits of this procedure with patients considering exenterative surgery.

Suture Granuloma in Rectal Anastomosis Mistaken for Locally Recurrent Cancer

1996 ◽  
Vol 23 (1) ◽  
pp. 78-79 ◽  
Author(s):  
Kazuoki Hizawa ◽  
Kunihiko Aoyagi ◽  
Hiroshi Suekane ◽  
Ryuichi Mibu ◽  
Takashi Yao ◽  
...  
Keyword(s):  
Rectal Anastomosis ◽  
Recurrent Cancer ◽  
Locally Recurrent
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