scholarly journals Adaptively Weighted Top-N Recommendation for Organ Matching

2022 ◽  
Vol 3 (1) ◽  
pp. 1-29
Author(s):  
Parshin Shojaee ◽  
Xiaoyu Chen ◽  
Ran Jin

Reducing the shortage of organ donations to meet the demands of patients on the waiting list has being a major challenge in organ transplantation. Because of the shortage, organ matching decision is the most critical decision to assign the limited viable organs to the most “suitable” patients. Currently, organ matching decisions are only made by matching scores calculated via scoring models, which are built by the first principles. However, these models may disagree with the actual post-transplantation matching performance (e.g., patient's post-transplant quality of life (QoL) or graft failure measurements). In this paper, we formulate the organ matching decision-making as a top-N recommendation problem and propose an Adaptively Weighted Top-N Recommendation (AWTR) method. AWTR improves performance of the current scoring models by using limited actual matching performance in historical datasets as well as the collected covariates from organ donors and patients. AWTR sacrifices the overall recommendation accuracy by emphasizing the recommendation and ranking accuracy for top-N matched patients. The proposed method is validated in a simulation study, where KAS [ 60 ] is used to simulate the organ-patient recommendation response. The results show that our proposed method outperforms seven state-of-the-art top-N recommendation benchmark methods.

1995 ◽  
Vol 166 (4) ◽  
pp. 521-524 ◽  
Author(s):  
Ian Collis ◽  
Andrew Burroughs ◽  
Keith Rolles ◽  
Geoffrey Lloyd

BackgroundThis study measures psychiatric morbidity, quality of life, and cognitive function after liver transplantation.MethodWe undertook a cross-sectional study, with a longitudinal subgroup. The setting was a tertiary referral centre for liver transplantation. The subjects were 30 post-liver-transplantation patients, including 11 also interviewed before the operation. The main outcome measures were the Clinical Interview Schedule (CIS), the General Health Questionnaire (GHQ), the Nottingham Health Profile (NHP), and the Mini-Mental State Examination (MMSE).ResultsOf the patients, 8/30 were CIS cases, and 7/30 were GHQ cases. NHP scores were higher than a previous postal study indicated, with less impairment after than before transplant. MMSE scores were 24–30. Median GHQ was 7.0 before operation and 1.0 after operation (P = 0.03), with no significant change in CIS score.ConclusionLiver transplantation improves quality of life, but not to the level of the general population; post-transplantation patients have a prevalence of psychiatric morbidity comparable with that of general medical patients.


Author(s):  
Huan Vu ◽  
Samir Aknine ◽  
Sarvapali D. Ramchurn

Traffic congestion has a significant impact on quality of life and the economy. This paper presents a decentralised traffic management mechanism for intersections using a distributed constraint optimisation approach (DCOP). Our solution outperforms the state of the art solution both for stable traffic conditions (about 60% reduced waiting time) and robustness to unpredictable events. 


Author(s):  
Brendan M. Hickey ◽  
Samuel T. Woo ◽  
Sally F. Shady

Lower limb deficiencies and below knee amputations are the most common form of deficiency that may arise from disease or trauma, and returning a patient close to a normal quality-of-life requires prosthetics, which can be quite challenging. Children present even further difficulty to prosthetists and physicians than adults. Although the underlying prosthetic principles for adults are the same for children, additional considerations must be made for practicality, such as downsizing while maintaining its degree of complexity, and frequent appointments to account for the rapid growth of an adolescent. This review article will evaluate the current state-of-the-art in the field of transtibial-amputee prosthetics, review the insurance coverage a typical family would face, and suggest potential improvements to children’s biomimetic prostheses that aid in reducing the frequency of health care provider intervention.


1995 ◽  
Vol 62 (2) ◽  
pp. 296-299
Author(s):  
F. Zattoni ◽  
F. Vianello

High incidences for prostatic cancer and mortality related to tumour have a serious impact on society. In these few last years there has been an emerging interest in the opportunity and possibility of a screening programme for this cancer. At present no certain data exist on the utility of a screening programme in asymptomatic males. The only proposable programme appears to be a pilot study to evaluate the capacity to reduce mortality related to prostate cancer or at least to improve the quality of life in cases diagnosed through a screening programme.


1998 ◽  
Vol 65 (12) ◽  
pp. S15
Author(s):  
A. Tejani ◽  
L. Donaldson ◽  
K. Lawry ◽  
K. McGowan ◽  
D. Dortar ◽  
...  

BMC Surgery ◽  
2013 ◽  
Vol 13 (Suppl 2) ◽  
pp. S15 ◽  
Author(s):  
Stefano Marventano ◽  
Maria Forjaz ◽  
Giuseppe Grosso ◽  
Antonio Mistretta ◽  
Gabriele Giorgianni ◽  
...  

2008 ◽  
Vol 11 (1) ◽  
pp. 250-258 ◽  
Author(s):  
María Ángeles Pérez San Gregorio ◽  
Agustín Martín Rodríguez ◽  
José Pérez Bernal

The aim of this investigation is to analyze the psychological differences of patients and their relatives according to the formers' post-transplantation anxiety. We used two groups of participants: transplant patients (n = 166) and close relatives (n = 166). Four questionnaires were applied: a Psychological Survey (to both groups), the Hospital Anxiety and Depression Scale, and the Quality of Life Questionnaire (to the transplant patients), and the Leeds Scales for the Self-Assessment of Anxiety and Depression (to the relatives). Participants were assessed twice: post-Intensive Care Unit (ICU; when patients were moved from the ICU to the Transplantation Unit) and post-hospital (one year after transplant). Results showed that high anxiety in patients just after organ transplant was related to an increase of anxiety and depression symptoms both in patients and relatives one year after transplant; it was also related to a decrease in the quality of life of these patients.


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