Reducing energy requirements for instruction issue and dispatch in superscalar microprocessors (poster session)

2000 ◽  
Author(s):  
Kanad Ghose
Keyword(s):  
Poster Session ◽  
Energy Requirements ◽  
Superscalar Microprocessors ◽  
Reducing Energy

scholarly journals Protection against CNS Ischemia by Temporary Interruption of Function-Related Processes of Neurons

1995 ◽  
Vol 15 (3) ◽  
pp. 433-439 ◽  
Author(s):  
Adelbert Ames ◽  
Kenneth I. Maynard ◽  
Stuart Kaplan
Keyword(s):  
Energy Consumption ◽  
Continuous Monitoring ◽  
Glucose Utilization ◽  
Complete Loss ◽  
Full Recovery ◽  
Energy Requirements ◽  
Ischemic Damage ◽  
Fold Reduction ◽  
Pharmacologic Agents ◽  
Reducing Energy

Previous studies have shown that most of the energy consumption of CNS tissue is used for processes that subserve signaling functions of the cells. Since these function-related processes are probably not essential to cell viability, blocking them reversibly with a combination of pharmacologic agents should protect cells from a reduction in energy metabolism. Preliminary experiments to test this hypothesis were performed on isolated rabbit retinas. They were maintained in a newly devised chamber that permitted continuous monitoring of electrophysiological function for ≥8 h. Ischemia was simulated by a 6-fold reduction in both O2 and glucose. This caused a rapid ( t1/2 75 s) and complete loss of the light-evoked response in the optic nerve. Untreated retinas showed full recovery after ½ h of deprivation, but only 50% recovery after 1 h and little or no recovery after 2 or 3 h. Retinas exposed during 3 h of deprivation to a combination of six agents that abolished electrophysiologic function and reduced glucose utilization [tetrodotoxin (TTX), 2-amino-4-phosphonobutyric acid (APB), 2-amino-5-phosphonovaleric acid (APV), amiloride, Mg2+, and Li+] showed full recovery. We conclude that reducing energy requirements by blocking functional processes can prevent ischemic damage.

Reducing energy requirements in unit operations

1976 ◽  
Vol 11 (3) ◽  
pp. 215-222 ◽  
Author(s):  
D.C. Freshwater ◽  
E. Ziogou
Keyword(s):  
Energy Requirements ◽  
Unit Operations ◽  
Reducing Energy
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