Constant density visualizations of non-uniform distributions of data

Author(s):  
Allison Woodruff ◽  
James Landay ◽  
Michael Stonebraker
Author(s):  
Marcel Escudier

The three fundamental principles for the variation of static pressure p throughout a body of fluid at rest are (a) the pressure at a point is the same in all directions (Pascal’s law), (b) the pressure is the same at all points on the same horizontal level, and (c) the pressure increases with depth z according to the hydrostatic equation. dp/dz= ρ‎g For a fluid with constant density ρ‎, the increase in pressure over a depth increase h is ρ‎gh, a result which can be used to analyse the response of simple barometers and manometers to applied pressure changes and differences. In situations where very large changes in pressure occur an equation of state may be required to relate pressure and density together with an assumption about the fluid temperature. The hydrostatic equation is still valid but more difficult to integrate, as illustrated by consideration of the earth’s atmosphere.


Author(s):  
Valentina Kuskova ◽  
Stanley Wasserman

Network theoretical and analytic approaches have reached a new level of sophistication in this decade, accompanied by a rapid growth of interest in adopting these approaches in social science research generally. Of course, much social and behavioral science focuses on individuals, but there are often situations where the social environment—the social system—affects individual responses. In these circumstances, to treat individuals as isolated social atoms, a necessary assumption for the application of standard statistical analysis is simply incorrect. Network methods should be part of the theoretical and analytic arsenal available to sociologists. Our focus here will be on the exponential family of random graph distributions, p*, because of its inclusiveness. It includes conditional uniform distributions as special cases.


Nature ◽  
2021 ◽  
Author(s):  
Stefanie Warnat-Herresthal ◽  
◽  
Hartmut Schultze ◽  
Krishnaprasad Lingadahalli Shastry ◽  
Sathyanarayanan Manamohan ◽  
...  

AbstractFast and reliable detection of patients with severe and heterogeneous illnesses is a major goal of precision medicine1,2. Patients with leukaemia can be identified using machine learning on the basis of their blood transcriptomes3. However, there is an increasing divide between what is technically possible and what is allowed, because of privacy legislation4,5. Here, to facilitate the integration of any medical data from any data owner worldwide without violating privacy laws, we introduce Swarm Learning—a decentralized machine-learning approach that unites edge computing, blockchain-based peer-to-peer networking and coordination while maintaining confidentiality without the need for a central coordinator, thereby going beyond federated learning. To illustrate the feasibility of using Swarm Learning to develop disease classifiers using distributed data, we chose four use cases of heterogeneous diseases (COVID-19, tuberculosis, leukaemia and lung pathologies). With more than 16,400 blood transcriptomes derived from 127 clinical studies with non-uniform distributions of cases and controls and substantial study biases, as well as more than 95,000 chest X-ray images, we show that Swarm Learning classifiers outperform those developed at individual sites. In addition, Swarm Learning completely fulfils local confidentiality regulations by design. We believe that this approach will notably accelerate the introduction of precision medicine.


2009 ◽  
Vol 83 (10) ◽  
pp. 925-942 ◽  
Author(s):  
Dimitrios Tsoulis ◽  
Olivier Jamet ◽  
Jérôme Verdun ◽  
Nicolas Gonindard

Author(s):  
Chang Yu ◽  
Daniel Zelterman

Abstract We develop the distribution for the number of hypotheses found to be statistically significant using the rule from Simes (Biometrika 73: 751–754, 1986) for controlling the family-wise error rate (FWER). We find the distribution of the number of statistically significant p-values under the null hypothesis and show this follows a normal distribution under the alternative. We propose a parametric distribution ΨI(·) to model the marginal distribution of p-values sampled from a mixture of null uniform and non-uniform distributions under different alternative hypotheses. The ΨI distribution is useful when there are many different alternative hypotheses and these are not individually well understood. We fit ΨI to data from three cancer studies and use it to illustrate the distribution of the number of notable hypotheses observed in these examples. We model dependence in sampled p-values using a latent variable. These methods can be combined to illustrate a power analysis in planning a larger study on the basis of a smaller pilot experiment.


2020 ◽  
Vol 9 (1) ◽  
pp. 93-104
Author(s):  
Mingrui Du ◽  
Yuan Gao ◽  
Guansheng Han ◽  
Luan Li ◽  
Hongwen Jing

AbstractMulti-walled carbon nanotubes (MWCNTs) have been added in the plain cementitious materials to manufacture composites with the higher mechanical properties and smart behavior. The uniform distributions of MWCNTs is critical to obtain the desired enhancing effect, which, however, is challenged by the high ionic strength of the cement pore solution. Here, the effects of methylcellulose (MC) on stabilizing the dispersion of MWCNTs in the simulated cement pore solution and the viscosity of MWCNT suspensions werestudied. Further observations on the distributions of MWCNTs in the ternary cementitious composites were conducted. The results showed that MC forms a membranous envelope surrounding MWCNTs, which inhibits the adsorption of cations and maintains the steric repulsion between MWCNTs; thus, the stability of MWCNT dispersion in cement-based composites is improved. MC can also work as a viscosity adjuster that retards the Brownian mobility of MWCNTs, reducing their re-agglomerate within a period. MC with an addition ratio of 0.018 wt.% is suggested to achieve the optimum dispersion stabilizing effect. The findings here provide a way for stabilizing the other dispersed nano-additives in the cementitious composites.


1968 ◽  
Vol 34 (1) ◽  
pp. 163-176 ◽  
Author(s):  
Francis E. Fendell

The flow induced by gravity about a very small heated isothermal sphere introduced into a fluid in hydrostatic equilibrium is studied. The natural-convection flow is taken to be steady and laminar. The conditions under which the Boussinesq model is a good approximation to the full conservation laws are described. For a concentric finite cold outer sphere with radius, in ratio to the heated sphere radius, roughly less than the Grashof number to the minus one-half power, a recirculating flow occurs; fluid rises near the inner sphere and falls near the outer sphere. For a small heated sphere in an unbounded medium an ordinary perturbation expansion essentially in the Grashof number leads to unbounded velocities far from the sphere; this singularity is the natural-convection analogue of the Whitehead paradox arising in three-dimensional low-Reynolds-number forced-convection flows. Inner-and-outer matched asymptotic expansions reveal the importance of convective transport away from the sphere, although diffusive transport is dominant near the sphere. Approximate solution is given to the nonlinear outer equations, first by seeking a similarity solution (in paraboloidal co-ordinates) for a point heat source valid far from the point source, and then by linearization in the manner of Oseen. The Oseen solution is matched to the inner diffusive solution. Both outer solutions describe a paraboloidal wake above the sphere within which the enthalpy decays slowly relative to the rapid decay outside the wake. The updraft above the sphere is reduced from unbounded growth with distance from the sphere to constant magnitude by restoration of the convective accelerations. Finally, the role of vertical stratification of the ambient density in eventually stagnating updrafts predicted on the basis of a constant-density atmosphere is discussed.


Solutions of the Einstein field equations are found for the problem of a sphere of constant density surrounded by matter of different constant density. The solutions are discussed and particular attention paid to the topology of the surrounding matter. The Schwarzschild, de Sitter, and Einstein solutions emerge as particular cases of the general problem.


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