Effets de deux mutations neurologiques, minibrain3 et no-bridgeKS49, sur la parade nuptiale chez Drosophila melanogaster

1993 ◽  
Vol 71 (5) ◽  
pp. 985-990 ◽  
Author(s):  
A. Bouhouche ◽  
T. Benziane ◽  
G. Vaysse
Keyword(s):  
Drosophila Melanogaster ◽  
Sequential Analysis ◽  
Low Frequency ◽  
Male Courtship ◽  
Protocerebral Bridge ◽  
Copulation Attempt ◽  
The Brain

Male courtship events of two neurological mutants (nobridgeKS49 (nob) and minibrain3 (mnb)) of Drosophila melanogaster were recorded and subjected to quantitative and sequential analysis. The nob mutation, which disorganizes the protocerebral bridge, causes specific defects in courtship: a low frequency of the copulation attempt and the disappearance of the licking – copulation attempt sequence. Thus, the nob males were unable to copulate with receptive females within the 30-min observation. We think that this may be due to an abnormality in their wing vibrations. The mnb mutant, characterized by a reduction of the brain (by more than 50%), exhibited difficulties in initiating courtship and in maintaining contact with the female during courtship. These courtship defects may be due to visual and locomotor anomalies.

scholarly journals IDENTIFICATION OF BRAIN SITES CONTROLLING FEMALE RECEPTIVITY IN MOSAICS OF DROSOPHILA MELANOGASTER

Genetics ◽  
1983 ◽  
Vol 103 (2) ◽  
pp. 179-195
Author(s):  
Laurie Tompkins ◽  
Jeffrey C Hall
Keyword(s):  
Drosophila Melanogaster ◽  
Minimum Amount ◽  
Male Courtship ◽  
Experimental Conditions ◽  
Female Receptivity ◽  
Female Genotype ◽  
Courtship Behaviors ◽  
Necessary And Sufficient ◽  
The Brain ◽  
Male Genotype

ABSTRACT We have identified cells in the brain of Drosophila melanogaster that are required to be of female genotype for receptivity to copulation with males. To do this, we determined experimental conditions in which female flies virtually always copulate, then measured the minimum amount of male courtship that is required to stimulate females to indicate their receptivity to copulation. We then observed gynandromorphs with female genitalia to determine whether the sex mosaics elicited at least the minimum amount of courtship and, if so, whether they copulated. By analyzing these gynandromorphs, in which the genotype of external and internal tissues could be ascertained, we were able to identify a group of cells in the dorsal anterior brain that, when bilaterally female, is necessary and sufficient for receptivity to copulation. This group of cells is anatomically distinct from those that are required to be of male genotype for the performance of courtship behaviors.

scholarly journals Transcriptome Analysis of NPFR Neurons Reveals a Connection Between proteome Diversity and Social Behavior

2020 ◽  
Author(s):  
Julia Ryvkin ◽  
Assa Bentzur ◽  
Anat Shmueli ◽  
Miriam Tannenbaum ◽  
Omri Shallom ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Social Behavior ◽  
Transcriptome Analysis ◽  
Molecular Signature ◽  
Transcription Profile ◽  
Male Courtship ◽  
Transcriptome Profile ◽  
Protein Ubiquitination ◽  
Spatiotemporal Regulation ◽  
The Brain

AbstractComplex social behaviors are mediated by the activity of highly intricate neuronal networks, the function of which is shaped by their transcriptomic and proteomic content. Contemporary advances in neurogenetics, genomics, and tools for automated behavior analysis make it possible to functionally connect the transcriptome profile of candidate neurons to their role in regulating behavior. In this study we used Drosophila melanogaster to explore the molecular signature of neurons expressing receptor for neuropeptide F (NPF), the fly homologue of neuropeptide Y (NPY). By comparing the transcription profile of NPFR neurons to those of nine other populations of neurons, we discovered that NPFR neurons exhibit a unique transcriptome, enriched with receptors for various neuropeptides and neuromodulators, as well as with genes known to regulate behavioral processes, such as learning and memory. By manipulating RNA editing and protein ubiquitination programs specifically in NPFR neurons, we demonstrate that their delicate transcriptome and proteome repertoires are required to suppress male courtship and certain features of social group interaction. Our results highlight the importance of transcriptome and proteome diversity in the regulation of complex behaviors and pave the path for future dissection of the spatiotemporal regulation of genes within highly complex tissues, such as the brain.

scholarly journals Transcriptome Analysis of NPFR Neurons Reveals a Connection Between Proteome Diversity and Social Behavior

2021 ◽  
Vol 15 ◽  
Author(s):  
Julia Ryvkin ◽  
Assa Bentzur ◽  
Anat Shmueli ◽  
Miriam Tannenbaum ◽  
Omri Shallom ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Social Behavior ◽  
Transcriptome Analysis ◽  
Molecular Signature ◽  
Transcription Profile ◽  
Male Courtship ◽  
Transcriptome Profile ◽  
Protein Ubiquitination ◽  
Spatiotemporal Regulation ◽  
The Brain

Social behaviors are mediated by the activity of highly complex neuronal networks, the function of which is shaped by their transcriptomic and proteomic content. Contemporary advances in neurogenetics, genomics, and tools for automated behavior analysis make it possible to functionally connect the transcriptome profile of candidate neurons to their role in regulating behavior. In this study we used Drosophila melanogaster to explore the molecular signature of neurons expressing receptor for neuropeptide F (NPF), the fly homolog of neuropeptide Y (NPY). By comparing the transcription profile of NPFR neurons to those of nine other populations of neurons, we discovered that NPFR neurons exhibit a unique transcriptome, enriched with receptors for various neuropeptides and neuromodulators, as well as with genes known to regulate behavioral processes, such as learning and memory. By manipulating RNA editing and protein ubiquitination programs specifically in NPFR neurons, we demonstrate that the proper expression of their unique transcriptome and proteome is required to suppress male courtship and certain features of social group interaction. Our results highlight the importance of transcriptome and proteome diversity in the regulation of complex behaviors and pave the path for future dissection of the spatiotemporal regulation of genes within highly complex tissues, such as the brain.

Changes in the Total Power of Beta and Theta Bands When Using EEG Biofeedback in Primary School-Age Children Having Difficulties with Voluntary Regulation

2020 ◽  
pp. 331-340
Author(s):  
Yuliya S. Dzhos ◽  
◽  
Irina A. Men’shikova ◽  
Keyword(s):  
Left Hemisphere ◽  
Spectral Characteristics ◽  
Low Frequency ◽  
School Age Children ◽  
Total Power ◽  
Eeg Biofeedback ◽  
Beta Band ◽  
Bioelectric Activity ◽  
Voluntary Regulation ◽  
The Brain

This article presents the results of the study on spectral electroencephalogram (EEG) characteristics in 7–10-year-old children (8 girls and 22 boys) having difficulties with voluntary regulation of activity after 10 and 20 neurofeedback sessions using beta-activating training. Brain bioelectric activity was recorded in 16 standard leads using the Neuron-Spectrum-4/VPM complex. The dynamics was assessed by EEG beta and theta bands during neurofeedback. An increase in the total power of beta band oscillations was established both after 10 and after 20 sessions of EEG biofeedback in the frontal (p ≤ 0.001), left parietal (p ≤ 0.036), and temporal (p ≤ 0.003) areas of the brain. A decrease in the spectral characteristics of theta band oscillations was detected: after 10 neurofeedback sessions in the frontal (p ≤ 0.008) and temporal (p ≤ 0.006) areas of both hemispheres, as well as in the parietal area of the left hemisphere (p ≤ 0.005); after 20 sessions, in the central (p ≤ 0.004), frontal (p ≤ 0.001) and temporal (p ≤ 0.001) areas of both hemispheres, as well as in the occipital (p ≤ 0.047) and parietal (p ≤ 0.001) areas of the left hemisphere. The study into the dynamics of bioelectric activity during biofeedback using EEG parameters in 7–10-year-old children with impaired voluntary regulation of higher mental functions allowed us to prove the advisability of 20 sessions, as the increase in high-frequency activity and decrease in low-frequency activity do not stop with the 10th session. Changes in these parameters after 10 EEG biofeedback sessions are expressed mainly in the frontotemporal areas of both hemispheres, while after a course of 20 sessions, in both the frontotemporal and central parietal areas of the brain.

scholarly journals Correction: The Nutrient-Responsive Hormone CCHamide-2 Controls Growth by Regulating Insulin-like Peptides in the Brain of Drosophila melanogaster

PLoS Genetics ◽  
2015 ◽  
Vol 11 (9) ◽  
pp. e1005481 ◽  
Author(s):  
Hiroko Sano ◽  
Akira Nakamura ◽  
Michael J. Texada ◽  
James W. Truman ◽  
Hiroshi Ishimoto ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
The Brain

scholarly journals Toward asleep DBS: cortico-basal ganglia spectral and coherence activity during interleaved propofol/ketamine sedation mimics NREM/REM sleep activity

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Jing Guang ◽  
Halen Baker ◽  
Orilia Ben-Yishay Nizri ◽  
Shimon Firman ◽  
Uri Werner-Reiss ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Rem Sleep ◽  
Standard Procedure ◽  
Low Frequency ◽  
Nrem Sleep ◽  
Sleep Cycle ◽  
Advanced Parkinson’S Disease ◽  
Low Frequency Power ◽  
The Brain ◽  
Frequency Power

AbstractDeep brain stimulation (DBS) is currently a standard procedure for advanced Parkinson’s disease. Many centers employ awake physiological navigation and stimulation assessment to optimize DBS localization and outcome. To enable DBS under sedation, asleep DBS, we characterized the cortico-basal ganglia neuronal network of two nonhuman primates under propofol, ketamine, and interleaved propofol-ketamine (IPK) sedation. Further, we compared these sedation states in the healthy and Parkinsonian condition to those of healthy sleep. Ketamine increases high-frequency power and synchronization while propofol increases low-frequency power and synchronization in polysomnography and neuronal activity recordings. Thus, ketamine does not mask the low-frequency oscillations used for physiological navigation toward the basal ganglia DBS targets. The brain spectral state under ketamine and propofol mimicked rapid eye movement (REM) and Non-REM (NREM) sleep activity, respectively, and the IPK protocol resembles the NREM-REM sleep cycle. These promising results are a meaningful step toward asleep DBS with nondistorted physiological navigation.

scholarly journals Highly Tissue Specific Expression of Sphinx Supports Its Male Courtship Related Role in Drosophila melanogaster

PLoS ONE ◽  
2011 ◽  
Vol 6 (4) ◽  
pp. e18853 ◽  
Author(s):  
Ying Chen ◽  
Hongzheng Dai ◽  
Sidi Chen ◽  
Luoying Zhang ◽  
Manyuan Long
Keyword(s):  
Drosophila Melanogaster ◽  
Male Courtship ◽  
Specific Expression ◽  
Tissue Specific ◽  
Tissue Specific Expression

scholarly journals Low Frequency Noise Remove from EEG Signal

2020 ◽  
Vol 9 (1) ◽  
pp. 1510-1513
Keyword(s):  
Human Brain ◽  
Random Noise ◽  
Low Frequency ◽  
Frequency Noise ◽  
Eeg Signal ◽  
Low Frequency Noise ◽  
Frequency Range ◽  
Average Value ◽  
Different Types ◽  
The Brain

The electrical activity of the brain recorded by EEG which used to detect different types of diseases and disorders of the human brain. There is contained a large amount of random noise present during EEG recording, such as artifacts and baseline changes. These noises affect the low -frequency range of the EEG signal. These artifacts hiding some valuable information during analyzing of the EEG signal. In this paper we used the FIR filter for removing low -frequency noise(<1Hz) from the EEG signal. The performance is measured by calculating the SNR and the RMSE. We obtained RMSE average value from the test is 0.08 and the SNR value at frequency(<1Hz) is 0.0190.

scholarly journals Protocerebral bridge neurons that regulate sleep in Drosophila melanogaster

2020 ◽  
Author(s):  
Jun Tomita ◽  
Gosuke Ban ◽  
Yoshiaki S. Kato ◽  
Kazuhiko Kume
Keyword(s):  
Drosophila Melanogaster ◽  
Brain Regions ◽  
Central Complex ◽  
Neuronal Circuit ◽  
Sleep Regulation ◽  
Synaptic Contacts ◽  
Protocerebral Bridge ◽  
Dopamine Signaling

AbstractThe central complex is one of the major brain regions that control sleep in Drosophila, but the circuitry details of sleep regulation have yet to be elucidated. Here, we show a novel sleep-regulating neuronal circuit in the protocerebral bridge (PB) of the central complex. Activation of the PB interneurons labeled by the R59E08-Gal4 and the PB columnar neurons in the R52B10-Gal4 promoted sleep and wakefulness, respectively. A targeted GFP reconstitution across synaptic partners (t-GRASP) analysis demonstrated synaptic contacts between these two groups of sleep-regulating PB neurons. Furthermore, we found that activation of a pair of dopaminergic (DA) neurons projecting to the PB (T1 DA neurons) decreased sleep. The wake-promoting T1 DA neurons and the sleep-promoting PB interneurons formed close associations. Dopamine 2-like receptor (Dop2R) knockdown in the sleep-promoting PB interneurons increased sleep. These results indicated that the neuronal circuit in the PB regulated by dopamine signaling mediates sleep-wakefulness.

Sign in / Sign up

Export Citation Format

Share Document