Tissue distribution and plasma levels of liver enzymes in phocid seals

1977 ◽  
Vol 55 (12) ◽  
pp. 1936-1941 ◽  
Author(s):  
D. St. Aubin ◽  
J. R. Geraci

The distributions of alanine aminotransferase (AIAT), aspartate aminotransferase (AspAT), ornithine carbamyl transferase (OCT), and sorbitol dehydrogenase (SDH) were determined in the tissues of ringed seals, Phoca hispida, harp seals, P. groenlandica, and grey seals, Halichoerus grypus. In all species, AIAT, OCT, and SDH were concentrated primarily in the liver, while AspAT had a more widespread distribution. Species differences were noted in the distribution of AspAT. In grey and harp seals cardiac muscle generally contained the greatest concentration of activity while in ringed seals the highest activity was found in the liver. Reference plasma values were determined in six clinically normal captive ringed seals.

2002 ◽  
Vol 119 (3) ◽  
pp. 399-412 ◽  
Author(s):  
Madeleine Nyman ◽  
Jaana Koistinen ◽  
Marie Louise Fant ◽  
Terttu Vartiainen ◽  
Eero Helle

1977 ◽  
Vol 34 (8) ◽  
pp. 1143-1147 ◽  
Author(s):  
F. Rainer Engelhardt ◽  
Joseph R. Geraci ◽  
Thomas G. Smith

Ringed seals, Phoca hispida, showed rapid absorption of hydrocarbons from Norman Wells crude oil into body tissues and fluids when exposed by both immersion and ingestion. Relatively low but significant levels were found in tissue, blood, and plasma. Levels in bile and urine were high, indicating these to be routes of excretion. Key words: petroleum, hydrocarbons, benzene, ringed seal, immersion, ingestion, uptake, clearance


2021 ◽  
Vol 10 (12) ◽  
pp. 2724
Author(s):  
Shira Azulai ◽  
Ronit Grinbaum ◽  
Nahum Beglaibter ◽  
Shai Meron Eldar ◽  
Moshe Rubin ◽  
...  

Patients that undergo bariatric surgery experience weight loss and a reduction in the plasma levels of the hepatic enzymes alanine aminotransferase (ALT) and aspartate aminotransferase (AST). We used the Israeli national bariatric registry, which includes demographic, clinical, and biochemical data on 19,403 patients, of which 1335 patients had two-year follow-up data on ALT, AST, A1C, and BMI, to test the dependence of the reduction in the levels of ALT and AST on weight loss. The data were analyzed using regression models, retrospective matching, and time course analyses. Changes in liver enzymes did not correlate with change in BMI, and linear regression models did not demonstrate that the change in ALT and AST values were dependent on pre-operative levels of BMI or the extent of weight loss. ALT and AST levels were reduced two years after surgery compared with a cohort of retrospectively matched patients for ethnicity, sex, age, BMI, and A1C. Finally, patients who regained weight displayed a reduction in levels of liver enzymes. Our results suggest that bariatric surgery affects AST and ALT levels via weight loss dependent and independent mechanisms. Mechanistic studies that will identify the nature of this effect and the clinical relevance of ALT and AST levels to the post-bariatric liver function are warranted.


AMBIO ◽  
2001 ◽  
Vol 30 (7) ◽  
pp. 397-409 ◽  
Author(s):  
Anders Bergman ◽  
Anders Bergstrand ◽  
Anders Bignert

1990 ◽  
Vol 47 (6) ◽  
pp. 1223-1227 ◽  
Author(s):  
Morten Ryg ◽  
Christian Lydersen ◽  
Nina H. Markussen ◽  
Thomas G. Smith ◽  
Nils Are Øritsland

We have investigated the relationships between percent blubber content and xiphostemal blubber thickness or girth-to-length ratios in ringed seal (Phoca hispida), harp seal (Phoca groeniandica), and grey seal (Halichoerus grypus). The blubber content was significantly correlated with blubber depths and girth-to-length ratios in all three species, in addition, we have developed an estimator for percent blubber content (the LMD-index) based on standard length (L, in meters), body mass (M, in kilograms), and on blubber thickness (d, in meters) measured at a defined position dorsally. From these variables the percent blubber content (B%) can be estimated by the expression B% = 4.44 + 5693 [Formula: see text], with a standard error of the estimate of three percentage units. This index also gave reasonable estimates for blubber content in three harbour seals (Phoca vitulina) and eight bearded seals (Erignatus harbatus).


1997 ◽  
Vol 75 (3) ◽  
pp. 359-370 ◽  
Author(s):  
Jean-François Gosselin ◽  
Lena N. Measures

The species Filaroides (Parafilaroides) gymnurus (Railliet, 1899) Anderson, 1978 is redescribed, based on examination of mature fifth-stage specimens from wild infected ringed seals (Phoca hispida), harp seals (Phoca groenlandica), harbour seals (Phoca vitulina), and grey seals (Halichoerus grypus) collected in eastern and arctic Canadian waters. Mature specimens of Filaroides (Parafilaroides) hispidus Kennedy, 1986 from ringed seals and grey seals were also examined. Comparison of these worms with museum specimens and the literature led to a review of species in the subgenus Parafilaroides (Dougherty, 1946) Anderson, 1978. Filaroides (Parafilaroides) gymnurus (Railliet, 1899) Anderson, 1978, F. (P.) decorus (Dougherty and Herman, 1947) Anderson, 1978, F. (P.) hydrurgae (Mawson, 1953) Kennedy, 1986, and F. (P.) hispidus Kennedy, 1986 are recognized as valid species. Filaroides (Parafilaroides) arcticus (Delyamure and Alekseev, 1966) Kennedy, 1986 and F. (P.) krascheninnikovi (Yurakhno and Skrjabin, 1971) Kennedy, 1986 are synonymized with F. (P.) gymnurus (Railliet, 1899) Anderson, 1978. Filaroides (Parafilaroides) caspicus (Kurochkin and Zablotsky, 1958) Kennedy, 1986 is considered a species inquirenda.


1979 ◽  
Vol 57 (10) ◽  
pp. 1985-1997 ◽  
Author(s):  
Kerwin J. Finley

Numbers of ringed seals hauled out on the ice began to increase in early June. Numbers on the ice were highest from 0900 to 1500 hours Central Standard Time and lowest (average 40–50% of peak) in early morning. Seals commonly remained on the ice for several hours, and occasionally (during calm weather) for > 48 h. Numbers on the ice were reduced on windy days and possibly also on unusually warm, bright and calm days. Seals tended to face away from the wind (particularly with high wind speed) and oriented broadside to the sun. Seals usually occurred singly (60–70% of all groups) at their holes.Numbers of seals hauled out at Freemans Cove remained relatively constant during June (maximum density 4.86/km2), whereas at Aston Bay numbers increased dramatically to a maximum density of 10.44/km2 in late June. The increase was thought to be due to an influx of seals abandoning unstable ice. The density of seal holes at Freemans Cove (5.92/km2) was much higher than at Aston Bay (2.73/km2). The ratio of holes to the maximum numbers of seals (1.12:1) at Freemans Cove represents a first estimate of this relationship in an apparently stable population.


1997 ◽  
Vol 54 (4) ◽  
pp. 914-921 ◽  
Author(s):  
N J Lunn ◽  
I Stirling ◽  
S N Nowicki

We flew a medium-altitude, systematic, strip-transect survey for ringed (Phoca hispida) and bearded seals (Erignathus barbatus) over western Hudson Bay in early June 1994 and 1995. The mean density (per square kilometre) of ringed seals hauled out on the ice was four times higher in 1995 (1.690) than in 1994 (0.380). The 1994 survey appeared to underestimate seal abundance because it was flown too late. Ringed seals preferred high ice cover habitat (6 + /8 ice) and, within this habitat, favoured cracking ice and large floes. We found no consistent effect of either wind or cloud cover on habitat preference. We estimated a total of 1980 bearded seals and 140<|>880 ringed seals hauled out on the sea ice in June 1995. A recent review of the relationship between ringed seal and polar bear (Ursus maritimus) populations suggests that a visible population of this size should support a population of up to 1300 polar bears, which is in general agreement with the current estimate of 1250-1300 bears in western Hudson Bay.


1992 ◽  
Vol 226 (4) ◽  
pp. 681-689 ◽  
Author(s):  
M. Ryg ◽  
Y. Solberg ◽  
C. Lydersen ◽  
T. G. Smith
Keyword(s):  

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