Decreased body-core temperature during acute hypoxemia in guinea pigs during postnatal maturation: a regulated thermoregulatory response

1996 ◽  
Vol 74 (3) ◽  
pp. 331-336 ◽  
Author(s):  
D J Clark ◽  
J E Fewell
Keyword(s):  
Core Temperature ◽  
Guinea Pigs ◽  
Body Core Temperature ◽  
Thermoregulatory Response ◽  
Postnatal Maturation ◽  
Body Core

The recommended Threshold Limit Values for heat exposure fail to maintain body core temperature within safe limits in older working adults

2017 ◽  
Vol 14 (9) ◽  
pp. 703-711 ◽  
Author(s):  
Dallon T. Lamarche ◽  
Robert D. Meade ◽  
Andrew W. D'Souza ◽  
Andreas D. Flouris ◽  
Stephen G. Hardcastle ◽  
...  
Keyword(s):  
Core Temperature ◽  
Heat Exposure ◽  
Body Core Temperature ◽  
Limit Values ◽  
Threshold Limit Values ◽  
Working Adults ◽  
Threshold Limit ◽  
Body Core ◽  
Safe Limits

Hypothalamic paraventricular nucleus is critical for renal vasoconstriction elicited by elevations in body temperature

2008 ◽  
Vol 294 (2) ◽  
pp. F309-F315 ◽  
Author(s):  
Joo Lee Cham ◽  
Emilio Badoer
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Blood Flow ◽  
Renal Blood Flow ◽  
Core Temperature ◽  
Paraventricular Nucleus ◽  
Hypothalamic Paraventricular Nucleus ◽  
Body Core Temperature ◽  
Control Group ◽  
Body Core

Redistribution of blood from the viscera to the peripheral vasculature is the major cardiovascular response designed to restore thermoregulatory homeostasis after an elevation in body core temperature. In this study, we investigated the role of the hypothalamic paraventricular nucleus (PVN) in the reflex decrease in renal blood flow that is induced by hyperthermia, as this brain region is known to play a key role in renal function and may contribute to the central pathways underlying thermoregulatory responses. In anesthetized rats, blood pressure, heart rate, renal blood flow, and tail skin temperature were recorded in response to elevating body core temperature. In the control group, saline was microinjected bilaterally into the PVN; in the second group, muscimol (1 nmol in 100 nl per side) was microinjected to inhibit neuronal activity in the PVN; and in a third group, muscimol was microinjected outside the PVN. Compared with control, microinjection of muscimol into the PVN did not significantly affect the blood pressure or heart rate responses. However, the normal reflex reduction in renal blood flow observed in response to hyperthermia in the control group (∼70% from a resting level of 11.5 ml/min) was abolished by the microinjection of muscimol into the PVN (maximum reduction of 8% from a resting of 9.1 ml/min). This effect was specific to the PVN since microinjection of muscimol outside the PVN did not prevent the normal renal blood flow response. The data suggest that the PVN plays an essential role in the reflex decrease in renal blood flow elicited by hyperthermia.

MK801 impairs thermoregulation in the heat

2002 ◽  
Vol 80 (3) ◽  
pp. 226-232 ◽  
Author(s):  
Frédéric Canini ◽  
Nadine Simler ◽  
Lionel Bourdon
Keyword(s):  
Locomotor Activity ◽  
Nmda Receptor ◽  
Receptor Antagonist ◽  
Core Temperature ◽  
Exposure Duration ◽  
Heat Exposure ◽  
Nmda Receptor Antagonist ◽  
Dopamine Metabolism ◽  
Body Core Temperature ◽  
Body Core

The effects of MK801 (dizocilpine), a glutamate NMDA receptor antagonist, on thermoregulation in the heat were studied in awake rats exposed to 40°C ambient temperature until their body core temperature reached 43°C. Under these conditions, MK801-treated rats exhibited enhanced locomotor activity and a steady rise in body core temperature, which reduced the heat exposure duration required to reach 43°C. Since MK801-treated rats also showed increased striatal dopaminergic metabolism at thermoneutrality, the role of dopamine in the MK801-induced impairment of thermoregulation in the heat was determined using co-treatment with SCH23390, a dopamine D1 receptor antagonist. SCH23390 normalized the locomotor activity in the heat without any effect on the heat exposure duration. These results suggest that the MK801-induced impairment of thermoregulation in the heat is related to neither a dopamine metabolism alteration nor a locomotor activity enhancement.Key words: heatstroke, NMDA receptor, thermoregulation, dopamine, locomotion.

Body Fatness, Body Core Temperature, and Heat Loss During Moderate-Intensity Exercise

2013 ◽  
Vol 84 (11) ◽  
pp. 1153-1158 ◽  
Author(s):  
Jayme D. Limbaugh ◽  
Gregory S. Wimer ◽  
Lynn H. Long ◽  
William H. Baird
Keyword(s):  
Heat Loss ◽  
Core Temperature ◽  
Body Core Temperature ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Body Fatness ◽  
Body Core

scholarly journals Measuring body core temperature using a novel non-invasive sensor

2015 ◽  
Vol 4 (S1) ◽  
Author(s):  
Yoram Epstein ◽  
Savyon Mazgaoker ◽  
Doron Gruber ◽  
Daniel S Moran ◽  
Ran Yanovich ◽  
...  
Keyword(s):  
Core Temperature ◽  
Body Core Temperature ◽  
Non Invasive ◽  
Body Core
Sign in / Sign up

Export Citation Format

Share Document