CORRELATION BETWEEN BODY HABITUS AND CROSS-SECTIONAL AREA OF RIBS

1965 ◽  
Vol 43 (5) ◽  
pp. 773-781 ◽  
Author(s):  
Hideaki Takahashi ◽  
Harold M. Frost

A correlation study was performed of the relationship between the total cross-sectional area of the fifth, sixth, or seventh rib in its middle third, and the height, weight, and sex of its owner. The study involved 115 metabolically normal people and yielded high correlation coefficients between the calculated and observed total rib cross-sectional areas of 60 males and 55 females. It is suggested that the total cross-sectional area at a standard bone sampling site be used as a basis for normalizing measures of the severity of osteoporosis. This would allow one to make improved comparisons of the severity of osteoporosis between persons of different body habitus and sex.

2016 ◽  
Vol 23 (2) ◽  
pp. 227-236 ◽  
Author(s):  
Dunja Perić ◽  
Paul A. Bartley ◽  
Lawrence Davis ◽  
Ali Ulvi Uzer ◽  
Cahit Gürer

AbstractLignin is a coproduct of biofuel and paper industries, which exhibits binding qualities when mixed with water. Lignin is an ideal candidate for a sustainable stabilization of unpaved roads. To this end, an experimental program was devised and carried out to quantify effects of lignin on compaction and early age shear strength behaviors of sand. Samples were prepared by mixing a particular type of coproduct called calcium lignosulfonate (CaL) with sand and water. Based on the extensive analyses of six series of strength tests, it was found that a normalized cohesion increased with an increasing normalized areas ratio. Normalizations were carried out by dividing the cohesion and area ratio by gravimetric CaL content whereby the area ratio was obtained by dividing the portion of the cross-sectional area occupied with lignosulfonate-water (CaL-W) paste by the total cross-sectional area. While the increase in the normalized cohesion eventually leveled out, the cohesion peaked at 6% of CaL. Thus, sand-CaL-water (S-CaL-W) mixes sustained larger shear stresses than dry sand for a range of normal stresses below the limiting normal stress. Consequently, the early age behavior indicates that adding CaL-W to sand is clearly beneficial in the near-surface applications in dry sand.


2002 ◽  
Vol 282 (4) ◽  
pp. G683-G689 ◽  
Author(s):  
J. D. Barlow ◽  
H. Gregersen ◽  
D. G. Thompson

Current techniques used to investigate the mechanisms responsible for the sensory responses to distension of the human esophagus provide limited information because the degree of circumferential stretch required to determine tension can only be inferred. We used impedance planimetry to measure the cross-sectional area during esophageal distension to ascertain the degree of stretch and tension that initiated motor and sensory responses. Hyoscine- N-butyl bromide (HBB), a cholinergic muscarinic receptor blocker, was also used to alter esophageal tension during distension. Motor activity was initiated at a lower degree of stretch and tension than that which initiated sensory awareness; both increased directly with increasing distension. HBB reduced both esophageal motility and tension during distension without altering the relationship between sensation intensity and cross-sectional area. Esophageal stretch, rather than tension, thus appears to be the major factor influencing sensory responses to esophageal distension.


2020 ◽  
Vol 9 (24) ◽  
Author(s):  
Gregory T. Adamson ◽  
Doff B. McElhinney ◽  
Yulin Zhang ◽  
Jeffrey A. Feinstein ◽  
Lynn F. Peng ◽  
...  

Background Due in part to the heterogeneity of the pulmonary circulation in patients with tetralogy of Fallot and major aortopulmonary collateral arteries (MAPCAs), research on this condition has focused on relatively basic anatomic characteristics. We aimed to detail pulmonary artery (PA) and MAPCA anatomy in a large group of infants, assess relationships between anatomy and early surgical outcomes, and consider systems for classifying MAPCAs. Methods and Results All infants ( <1 year of age) undergoing first cardiac surgery for tetralogy of Fallot/MAPCAs from 2001 to 2019 at Stanford University were identified. Preoperative angiograms delineating supply to all 18 pulmonary segments were reviewed for details of each MAPCA and the arborization and size of central PAs. We studied 276 patients with 1068 MAPCAs and the following PA patterns: 152 (55%) incompletely arborizing PAs, 48 (17%) normally arborizing PAs, 45 (16%) absent PAs, and 31 (11%) unilateral MAPCAs. There was extensive anatomic variability, but no difference in early outcomes according to PA arborization or the predominance of PAs or MAPCAs. Patients with low total MAPCA and/or PA cross‐sectional area were less likely to undergo complete repair. Conclusions MAPCA anatomy is highly variable and essentially unique for each patient. Though each pulmonary segment can be supplied by a MAPCA, central PA, or both, all anatomic combinations are similarly conducive to a good repair. Total cross‐sectional area of central PA and MAPCA material is an important driver of outcome. We elucidate a number of novel associations between anatomic features, but the extreme variability of the pulmonary circulation makes a granular tetralogy of Fallot/MAPCA classification system unrealistic.


1990 ◽  
Vol 68 (1) ◽  
pp. 187-192 ◽  
Author(s):  
K. K. Kirchner ◽  
J. T. McBride

We have previously shown that airway cross-sectional area increases 15-20% after pneumonectomy in weanling ferrets by measuring bronchial casts. We have now reanalyzed these same casts to quantitate changes in airway length after pneumonectomy. In each cast the distance from each of 120 airways to the terminal bronchiole along its axial pathway was measured. The relationship between the logarithm of this distance and that of the fraction of the lobe subtended by an airway could be described by a quadratic equation with a correlation coefficient greater than 0.85. Subsegmental and more distal airways of postpneumonectomy animals were 33-47% longer than those of controls. Overall the main axial pathway of airways in the left lower lobes was 12% longer in operated animals, but this increase was primarily accounted for by an increase in the length of the more peripheral airways. Central airways were little if any longer in operated animals. After pneumonectomy in weanling ferrets, subsegmental and peripheral airway lengths increase to a greater degree than lung volume and airway cross-sectional area, whereas central airway lengths increase to a lesser extent if at all. The mechanisms responsible for this difference between central and intralobar compensatory airway growth are unknown.


Author(s):  
Charles H. Turner ◽  
Alexander G. Robling

The accumulation of bone mass during growth can be enhanced by environmental factors such as mechanical loading (exercise) or calcium intake, but 60–70% of the variance in adult bone mineral density (BMD) is explained by heredity. Consequently, understanding the signaling pathways targeted by the genes governing bone accumulation holds perhaps the greatest potential in reducing fracture incidence later in life. Rodent models are particularly useful for studying the genetics of skeletal traits. Of the available inbred mouse strains, three in particular have been studied extensively in skeletal genetics: C57BL/6, DBA/2, and C3H/He. The C57BL/6 strain is characterized by low BMD and large total cross-sectional area (CSA) in the midshaft femur; the C3H/He strain exhibits very high femoral BMD and a smaller femoral CSA than the C57BL/6 mice; and DBA/2 mice have moderately high femoral BMD and a very small midshaft femur CSA. Mechanical loading of the skeleton during growth can substantially enhance periosteal bone apposition, and ultimately produce a diaphyseal cross section with enlarged area. Therefore we hypothesized that the mouse strain with greater femoral cross-sectional area (C57BL/6) might have a genetic predisposition for greater mechanosensitivity than mice with smaller cross sections (C3H/He and DBA/2).


1997 ◽  
Vol 82 (3) ◽  
pp. 954-958 ◽  
Author(s):  
R. W. Mitchell ◽  
E. Rühlmann ◽  
H. Magnussen ◽  
N. M. Muñoz ◽  
A. R. Leff ◽  
...  

Mitchell, R. W., E. Rühlmann, H. Magnussen, N. M. Muñoz, A. R. Leff, and K. F. Rabe. Conservation of bronchiolar wall area during constriction and dilation of human airways. J. Appl. Physiol. 82(3): 954–958, 1997.—We assessed the effect of smooth muscle contraction and relaxation on airway lumen subtended by the internal perimeter ( A i) and total cross-sectional area ( A o) of human bronchial explants in the absence of the potential lung tethering forces of alveolar tissue to test the hypothesis that bronchoconstriction results in a comparable change of A iand A o. Luminal area (i.e., A i) and A owere measured by using computerized videomicrometry, and bronchial wall area was calculated accordingly. Images on videotape were captured; areas were outlined, and data were expressed as internal pixel number by using imaging software. Bronchial rings were dissected in 1.0- to 1.5-mm sections from macroscopically unaffected areas of lungs from patients undergoing resection for carcinoma, placed in microplate wells containing buffered saline, and allowed to equilibrate for 1 h. Baseline, A o[5.21 ± 0.354 (SE) mm2], and A i(0.604 ± 0.057 mm2) were measured before contraction of the airway smooth muscle (ASM) with carbachol. Mean A inarrowed by 0.257 ± 0.052 mm2in response to 10 μM carbachol ( P = 0.001 vs. baseline). Similarly, A onarrowed by 0.272 ± 0.110 mm2in response to carbachol ( P = 0.038 vs. baseline; P = 0.849 vs. change in A i). Similar parallel changes in cross-sectional area for A iand A owere observed for relaxation of ASM from inherent tone of other bronchial rings in response to 10 μM isoproterenol. We demonstrate a unique characteristic of human ASM; i.e., both luminal and total cross-sectional area of human airways change similarly on contraction and relaxation in vitro, resulting in a conservation of bronchiolar wall area with bronchoconstriction and dilation.


2017 ◽  
Vol 45 (3) ◽  
pp. 222-227 ◽  
Author(s):  
E. Kajisa ◽  
H. Tohara ◽  
A. Nakane ◽  
Y. Wakasugi ◽  
K. Hara ◽  
...  

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