Studies on the BAL2 mechanism for ester hydrolysis

1993 ◽  
Vol 71 (11) ◽  
pp. 1841-1844 ◽  
Author(s):  
Judy E. Douglas ◽  
Grant Campbell ◽  
Donald C. Wigfield
Keyword(s):  
Spectral Analysis ◽  
Carboxylic Acid ◽  
Alkaline Hydrolysis ◽  
Ester Hydrolysis ◽  
Mass Spectral Analysis ◽  
Mass Spectral ◽  
Hydrolysis Of

The preparation and alkaline hydrolysis of 18O-methyl 2,2-dimethylpropanoate and 18O-methyl triphenylacetate are reported. From mass spectral analysis of the carboxylic acid products, it is concluded that the former substrate is hydrolyzed exclusively by the BAC2 mechanism, whereas the latter substrate proceeds 95% by the BAC2 mechanism and 5% by the BAL2 mechanism. The balance between these two mechanisms is discussed.

scholarly journals SYNTHESIS, CHARACTERIZATION, AND ANTHELMINTIC ACTIVITY OF NOVEL BENZOTHIAZOLE DERIVATIVES CONTAINING INDOLE MOIETIES

2019 ◽  
pp. 321-325
Author(s):  
ALETI RAJAREDDY ◽  
SRINIVAS MURTHY M
Keyword(s):  
Spectral Analysis ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Magnetic Resonance ◽  
Fourier Transform Infrared Spectroscopy ◽  
Anthelmintic Activity ◽  
Mass Spectral Analysis ◽  
Standard Drug ◽  
Mass Spectral ◽  
Benzothiazole Derivatives

Objective: The objective of this study was to synthesize and evaluate the anthelmintic activity (AA) of novel benzothiazole derivatives containing indole moieties (BDIM). Methods: The present works which involve the substituted isatin Schiff bases undergo acetylating and reacting with 2-aminobenzothiazole to give novel BDIM. Results: All the newly synthesized molecules (5a-5o) were characterized by Fourier-transform infrared spectroscopy, H_nuclear magnetic resonance, and mass spectral analysis along with physical data. The biological potentials of the newly synthesized compounds are evaluated for their AA using an Indian earthworm (Pheretima posthuma), and albendazole was used as standard drug. Conclusion: The synthesized compound 5f, 5n, and 5o showed good AA, whereas others exhibited significant activities.

Large-scale mass spectral analysis by simplex pattern recognition

1976 ◽  
Vol 48 (12) ◽  
pp. 1768-1774 ◽  
Author(s):  
T. Fai. Lam ◽  
Charles L. Wilkins ◽  
Thomas R. Brunner ◽  
Leonard J. Soltzberg ◽  
Steven L. Kaberline
Keyword(s):  
Pattern Recognition ◽  
Spectral Analysis ◽  
Large Scale ◽  
Mass Spectral Analysis ◽  
Mass Spectral
Sign in / Sign up

Export Citation Format

Share Document