Determination of amphetamine, cocaine, and heroin vapour pressures using a dynamic gas blending system and gas chromatographic analysis

A dynamic gas blending system was used to generate controlled vapour concentrations of amphetamine, cocaine, or heroin. An adsorption – thermal desorption – gas chromatographic procedure was developed and used to measure the output vapour concentrations. The vapour pressure of amphetamine at 20 °C was determined, and vapour pressures as a function of temperature have been measured for cocaine and heroin.