Rate enhancements for the nickel(II)–PADA complexation in mixed anionic micelles

1983 ◽  
Vol 61 (7) ◽  
pp. 1594-1597 ◽  
Author(s):  
Paul D. I. Fletcher ◽  
Joanne R. Hicks ◽  
Vincent C. Reinsborough
Keyword(s):  
Kinetic Analysis ◽  
Mixed Micelle ◽  
Mixed Micelles ◽  
Sodium Dodecylsulfate ◽  
Electrostatic Forces ◽  
Rate Enhancement ◽  
The Third ◽  
Micellar Systems ◽  
Sodium Decylsulfate ◽  
Anionic Micelles

Rate enhancements for the [Formula: see text] and pyridine-2-azo-p-dimethylaniline (PADA) reaction have been obtained in four simple equimolar binary micellar systems: sodium dodecylsulfate – sodium decylsulfate, sodium dodecylsulfate – sodium octylsulfate, sodium octylsulfate – sodium hexylsulfate, and sodium octylsulfate – sodium octanesulfonate. The rate enhancement curves were similar to those obtained for pure surfactants and were consistent with a 1:1 mixed micelle except for the third system where the micelle was richer in sodium octylsulfate. The kinetic analysis revealed no dramatic changes in hydrophobic or electrostatic forces on forming the mixed micelles

Comparison Between Interaction of Hydrophobic-anionic and Hydrophobic-cationic Mixed Micellar System with Drug Ciprofloxacin

2021 ◽  
Vol 37 (6) ◽  
pp. 1376-1386
Author(s):  
V.C. Ezhilrani ◽  
Vigneshwari. R ◽  
Sasmita Dash
Keyword(s):  
Molecular Weight ◽  
Complex Formation ◽  
Mixed Micelle ◽  
Mixed Micelles ◽  
Micellar System ◽  
Cetylpyridinium Bromide ◽  
Micellar Systems ◽  
Wide Range ◽  
Infrared Studies ◽  
The Individual

The interaction studies of drug ciprofloxacin with two mixed micellar systems are reported. The mixed micelles comprise a nonionic hydrophobic surfactant, pluronic L-81, an anionic surfactant, Ammonium dodecyl sulfate (ADS); and a cationic surfactant, Cetylpyridinium bromide (CPB). The various combinations chosen were L-81-ADS and L-81-CPB. The properties of both the mixed micelles were compared. Spectrophotometric, conductometric, co-solvent effect, and Infrared studies were used for the investigations. The studies were carried out in a wide range of mixed micellar concentrations in the post micellar region of the individual surfactants. The solubilization of drug CPX in the L-81-ADS was higher than that in L-81-CPB mixed micelle, as evidenced by UV studies. Ethanol and ethylene glycol were found to be effective co-solvents for both the mixed micellar systems. The conductivity studies of CPX with ADS and CPB surfactants, displayed a higher value of conductance for CPX and ADS, from 0.37µs-1 to 0.74µs-1 compared to CPX and CPB. The drug-mixed micelle displayed a higher molecular weight complex formation as seen from the IR spectra.

Micellar rate enhancement studies in mixed sodium fluorocarbon/hydrocarbon surfactant solutions

1992 ◽  
Vol 70 (6) ◽  
pp. 1581-1585 ◽  
Author(s):  
Terrence J. Connolly ◽  
Vincent C. Reinsborough
Keyword(s):  
Mixed Micelles ◽  
Anionic Surfactants ◽  
Binding Constants ◽  
Kinetic Studies ◽  
Bulk Solution ◽  
Reaction Volume ◽  
Sodium Decylsulfate ◽  
The Difference ◽  
Anionic Micelles ◽  
Robinson Equation

Stopped-flow kinetic studies were conducted in mixed micellar solutions of fluorocarbon and hydrocarbon anionic surfactants to determine the prevalent micellar form. The probe reaction was the Niaq2+/pyridine-2-azo-p-dimethylaniline (PADA) complexation, which is many times accelerated in the presence of anionic micelles. Binding constants for Niaq2+ and PADA partitioning between bulk solution and micelles were determined through the murexide technique and solubility measurements respectively and the molar reaction volume was obtained from the Robinson equation. The three binary surfactant systems investigated had sodium perfluoroheptanoate as the fluorocarbon surfactant while the hydrocarbon surfactants were sodium decylsulfate, sodium nonanesulfonate, and sodium octanesulfonate. The kinetic results were consistent with unimicellar composition in all three systems which was not the behaviour previously found with the sodium octane sulfonate/sodium perfluoroctanoate system. The difference was attributed to closer similarity in the surfactant pair hydrophobicities as revealed through their critical micelle concentrations. Another finding was that mixed micelles synergistically can lead to a much greater solubilization of PADA than is possible through either of the pure surfactants.

Micellar properties of zwitterionic surfactant - alkoxyethanol mixed micelles

2004 ◽  
Vol 82 (7) ◽  
pp. 1223-1229 ◽  
Author(s):  
Maria K Mullally ◽  
D Gerrard Marangoni
Keyword(s):  
Mixed Micelles ◽  
Hydrophobic Interactions ◽  
Mixed Solvents ◽  
Sodium Dodecylsulfate ◽  
Micelle Formation ◽  
Alcohol Concentration ◽  
Zwitterionic Surfactant ◽  
Micellar Systems ◽  
Aggregation Numbers ◽  
Ethoxylated Alcohols

The micelle formation process for a zwitterionic surfactant, N-dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate (ZW3-12), has been investigated in a series of mixed solvents consisting of different concentrations of ethoxylated alcohols and polymers. The critical micelle concentrations (cmc values) of the aggregates were determined by fluorescence spectroscopy, and the surfactant aggregation numbers were obtained from luminescence probing experiments. The cmc values for ZW3-12 changed very little in the presence of increasing amounts of poly(ethyleneoxide) (PEO) in the mixed solvent. In the case of the ethoxylated alcohol – ZW3-12 systems, the cmc values and aggregation numbers decreased systematically with increasing alcohol concentration. However, the cmc values of the mixed micelles showed little dependence on the number of ethylene oxide (EO) groups at constant alcohol concentration. These results are compared with the well-studied sodium dodecylsulfate – ethoxylated alcohol, and dodecyltrimethylammonium bromide – ethoxylated alcohol mixed micellar systems and to SDS–PEO systems and are discussed in terms of the contribution of the EO groups to the hydrophobic interactions. Key words: zwitterionic surfactant, alcohols, mixed micelles, luminescence probing.

Surfactant structure and micellar rate enhancements: Comparison within a related group of one-tailed, two-tailed and two-headed anionic surfactants

1984 ◽  
Vol 37 (8) ◽  
pp. 1593 ◽  
Author(s):  
DJ Jobe ◽  
VC Reinsborough
Keyword(s):  
Kinetic Analysis ◽  
Anionic Surfactants ◽  
Stopped Flow ◽  
Micellar Solutions ◽  
Polar Head ◽  
The Third ◽  
Related Group

Rate enhancements for the reaction between Ni2+(aq) and pyridine-2-azo-p-dimethylaniline (pada) have been investigated by the stopped-flow technique in micellar solutions of a related group of anionic surfactants: the sodium alkoxycarbonylmethanesulfonates, the sodium 1,2-bis(alkoxy- carbonyl)ethanesulfonates, and the disodium 4-alkyl3-sulfonatosuccinates. The second group differs from the first in having an extra identical tail and the third from the first by having an extra polar head. The hexyl, octyl and decyl members of each group were chosen for study except for the second group where the decyl member proved insoluble. The kinetic analysis revealed that adding a second tail did not dramatically increase the binding of pada to the micelles so that rate enhancements were not much increased. Adding a second head decreased the binding of Ni2+ ion to the micelles so that the third group appears to have no advantages in rate enhancements.

Influence of taurocholate, taurochenodeoxycholate, and taurodehydrocholate on sulfobromophthalein transport into bile.

1979 ◽  
Vol 236 (1) ◽  
pp. E10
Author(s):  
S Binet ◽  
Y Delage ◽  
S Erlinger
Keyword(s):  
Bile Salts ◽  
Mixed Micelle ◽  
Mixed Micelles ◽  
Important Determinant ◽  
Micelle Formation ◽  
Similar Increase ◽  
Mixed Micelle Formation ◽  
Series Of Experiments

To test the hypothesis that incorporation of sulfobromophthalein (BSP) into mixed micelles could account for the increase in its biliary transport maximum (Tmax) by bile salts, we have compared in hamsters the influence on BSP Tmax of taurocholate and taurochenodeoxycholate (two micelle-forming physiological bile salts) to that of taurodehydrocholate, a bile salt which, in vitro, does not form micelles. In a first series of experiments, it was observed that taurocholate and taurochenodeoxycholate increased the secretion of phospholipid (40 and 53%, respectively), and cholesterol (50 and 110%, respectively), whereas taurodehydrocholate decreased the secretion of phospholipid (-31%) and cholesterol (-43%). This result suggests that, in vivo, taurodehydrocholate or its metabolites do not form mixed micelles. In a second series of experiments, it was seen that the three bile salts induced a similar increase in BSP Tmax (63% with taurocholate, 52% with taurochenodeoxycholate, and 51% with taurodehydrocholate). These results provide circumstantial evidence for the hypothesis that mixed micelle formation is not an important determinant of maximal BSP secretion into bile.

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