Mass Spectrometry in Structural and Stereochemical Problems. CCXVII. Electron Impact Promoted Fragmentation of O-Methyl Oximes of some α,β-Unsaturated Ketones and Methyl Substituted Cyclohexanones

1972 ◽  
Vol 50 (17) ◽  
pp. 2776-2785 ◽  
Author(s):  
Younus M. Sheikh ◽  
Raymond J. Liedtke ◽  
A. M. Duffield ◽  
Carl Djerassi
Keyword(s):  
Mass Spectrometry ◽  
Electron Impact ◽  
High Resolution Mass Spectrometry ◽  
Unsaturated Ketone ◽  
Deuterium Labeling ◽  
Oxime Ether ◽  
Ether Group ◽  
Unsaturated Ketones ◽  
Carbonyl Derivatives ◽  
Mass Spectrometric Fragmentation

Deuterium labeling and high resolution mass spectrometry have been utilized to delineate the modes of mass spectrometric fragmentation of O-methyl oximes of α,β-unsaturated ketones and methyl substituted cyclohexanones. α,β-Unsaturated ketone and 2- and 4-methylcyclohexanone O-methyl oxime ether derivatives fragment upon electron impact in a manner reminiscent of the carbonyl derivatives from which they were prepared. However, several fragmentation sequences characteristic of the O-methyl oxime ether group were observed.

The Electron Impact Induced Fragmentation of 1-Aryl-5-hydroxy-1,2,3-triazole-4-carboxamides

1990 ◽  
Vol 43 (12) ◽  
pp. 2021 ◽  
Author(s):  
AT Lebedev ◽  
TY Samguina ◽  
T Blumenthal ◽  
MY Kolobov
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Kinetic Energy ◽  
Electron Impact ◽  
High Resolution Mass Spectrometry ◽  
Energy Spectra ◽  
Molecular Ion ◽  
High Resolution Mass ◽  
Ion Kinetic Energy ◽  
Resolution Mass

The pathways of the electron impact induced fragmentation of 1-aryl-5- hydroxy-1,2,3-triazole-4-carboxamides were studied. The compositions of the key ions were confirmed by high-resolution mass spectrometry. The proposed pathways were established from mass analysed ion kinetic energy spectra, and B/E and B2/E linked scans. A variety of structures for the molecular ion of the title compounds is proposed.

Electron impact studies. XXXI. Skeletal-rearrangement fragments in the mass spectra of anils

1968 ◽  
Vol 21 (8) ◽  
pp. 2021 ◽  
Author(s):  
JH Bowie ◽  
RG Cooks ◽  
JW Fisher ◽  
T McL Spotswood
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Electron Impact ◽  
Mass Spectra ◽  
General Type ◽  
High Resolution Mass Spectrometry ◽  
Aromatic Aldehydes ◽  
Skeletal Rearrangement ◽  
Rearrangement Processes ◽  
Resolution Mass

Skeletal-rearrangement fragments are observed in the mass spectra of all anils derived from aromatic aldehydes. The rearrangement processes have been studied by high-resolution mass spectrometry and in certain cases by deuterium labelling. All processes are of the general type [ABC]+ → [AC]+ +B.

scholarly journals An efficient synthesis of furan-3(2 H )-imine scaffold from alkynones

2021 ◽  
Vol 8 (11) ◽  
Author(s):  
Anas J. Rasras ◽  
Ihsan A. Shehadi ◽  
Eyad A. Younes ◽  
Da'san M. M. Jaradat ◽  
Raed A. AlQawasmeh
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Efficient Method ◽  
High Resolution Mass Spectrometry ◽  
Tertiary Alcohol ◽  
Efficient Synthesis ◽  
Unsaturated Ketones ◽  
Resolution Mass

A novel efficient method to generate spiro furan-3(2 H )-imine derivatives is established by the reaction between the α , β -unsaturated ketones and aniline derivatives. The reaction involves 1,4- addition of aniline followed by the subsequent intramolecular cyclization mediated by tertiary alcohol to produce the furan-3(2 H )-imine. All the synthesized compounds are characterized using nuclear magnetic resonance and high-resolution mass spectrometry (HRMS).

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