Inner glucosides of the anomeric 2-O-(2-hydroxyethyl)-D-glucoses

It has been found that 2-O-(2-hydroxyethyl)-D-glucopyranose is partially converted to 1,2-O-ethylene-α-D-glucofuranose, 1,2-O-ethylene-α-D-glucopyranose, and 1,2-O-ethylene-β-D-glucopyranose when heated in dilute acid solution. The ratio of the furanose derivative to the pyranose derivatives is dependent upon the concentration of the acid (3, 5). The three inner glucosides of 2-O-(2-hydroxyethyl)-D-glucose have been characterized by gas-liquid chromatography. The interrelationship of 2-O-(2-hydroxyethyl)-D-glucose and its inner glucosides is also reported.