scholarly journals THE ALDOL CONDENSATION WITH 2,3-DIPHENYL-4-THIAZOLIDINONE

1963 ◽  
Vol 41 (4) ◽  
pp. 817-820 ◽  
Author(s):  
Frances C. Brown ◽  
R. Sidney Jones ◽  
Mildred Kent
Keyword(s):  
Spectral Data ◽  
Aldol Condensation ◽  
Aromatic Aldehydes

The aldol condensation between 2,3-diphenyl-4-thiazolidinone and aromatic aldehydes, which cannot be effected by the usual catalysts used in the analogous reactions of 2-thiono-, 2-oxo-, and 2-imino-4-thiazolidinones, was achieved by the use of ethoxide ion. The structure of the 2,3-diphenyl-5-arylidene-4-thiazolidinone was confirmed by ultraviolet spectral data.

Synthesis and Pharmacological Evaluation of New 2-aryl-3, 4-dihydro-4-oxo Quinazolin [2,3-b]-2,3-dihydro-4-phenyl [1,3,4] Thiadiazepines

1970 ◽  
Vol 2 (4) ◽  
pp. 756-761
Author(s):  
B. Shiva kumar ◽  
Navnath V. Kalyane ◽  
B. Shivaram Krishna ◽  
B. Shireesha ◽  
V. M. Reddy
Keyword(s):  
Animal Models ◽  
Acetic Anhydride ◽  
Spectral Data ◽  
Muscle Relaxant ◽  
Aldol Condensation ◽  
Cycloaddition Reaction ◽  
Aromatic Aldehydes ◽  
Anti Psychotic ◽  
Standard Methods ◽  
Anthranilic Acids

Three different 3-amino-2-mercaptoquinazolin-4(3H)-ones were prepared from the substituted anthranilic acids. Likewise four different chalcones were also prepared by mixed aldol condensation of four aromatic aldehydes with acetophenone. Each of the 3-amino, 2-mercapto quinazolinones was subjected to a cycloaddition reaction with chalcones, separately by heating under reflux in acetic anhydride. The product obtained in each case has been purified and characterized as the respective 2-aryl-3,4-dihydro-4-oxoquinazolin-[2,3-b]-2,3-dihydro-4-phenyl –1,3,4-thiadiazepine on the basis of  their analytical and spectral data.             These new fused thiadiazepines were evaluated for their locomotor, anti psychotic and muscle relaxant activities by standard methods using animal models and compared with that of standard employed

scholarly journals Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives

2009 ◽  
Vol 6 (3) ◽  
pp. 866-870
Author(s):  
CH. Sridevi ◽  
K. Balaji ◽  
A. Naidu ◽  
R. Sudhakaran
Keyword(s):  
Spectral Data ◽  
Aromatic Aldehydes ◽  
Antimicrobial Activities ◽  
Methylene Bridge ◽  
Quinoxaline Derivatives ◽  
Antimicrobial Evaluation

2,3-Diphenyl quinoxaline(SI)was fused with 2-amino benzothiazoles(SII)by a methylene bridge, which was then allowed for acetylation. The acetylated product (SIV) was made to react with different aromatic aldehydes to give chalcones(SV1-SV5). Chalcones refluxed with substituted acid hydrazides to afford different phenyl pyrazolo benzothiazolo quinoxaline derivatives(SVI1-SVI15). The structure of chalcones and phenyl pyrazolo benzothiazolo quinoxaline derivatives were confirmed by M.P, TLC and spectral data. All the synthesized compounds were screened for their antimicrobial activities.

Synthesis of renewable aviation fuel additives with aromatic aldehydes and methyl isobutyl ketone under solvent-free conditions

2021 ◽  
Author(s):  
Fengan Han ◽  
Jingyuan Xu ◽  
Guangyi Li ◽  
Jilei Xu ◽  
Aiqin Wang ◽  
...  
Keyword(s):  
Methyl Isobutyl Ketone ◽  
Aldol Condensation ◽  
Freezing Point ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Aviation Fuel ◽  
Fuel Additives ◽  
Methyl Isobutyl ◽  
Isobutyl Ketone ◽  
Solvent Free Conditions

High-density and low freezing point dicycloalkanes were synthesized by the aldol condensation of methyl isobutyl ketone with aromatic aldehydes followed by hydrodeoxygenation under solvent-free conditions.

New Aspects of the Aldol Condensation of Acetylpyridines with Aromatic Aldehydes.

ChemInform ◽  
2005 ◽  
Vol 36 (3) ◽  
Author(s):  
S. Z. Vatsadze ◽  
V. N. Nuriev ◽  
I. F. Leshcheva ◽  
N. V. Zyk
Keyword(s):  
Aldol Condensation ◽  
Aromatic Aldehydes

scholarly journals Synthesis, Spectral Studies and Anti-Inflammatory Activity of 2-Acetyl Thiophene

2010 ◽  
Vol 7 (2) ◽  
pp. 433-436 ◽  
Author(s):  
B. Ramesh ◽  
B. Someswara Rao
Keyword(s):  
Spectral Data ◽  
Aromatic Aldehydes ◽  
Inflammatory Activity ◽  
Spectral Studies ◽  
Anti Inflammatory

Some new chalcones have been synthesized by the condensation of 2-acetyl thiophene with various aromatic aldehydes in 40% alkali. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.

Synthesis and Anticonvulsant Studies of Thiazolidinone and Azetidinone Derivatives from Indole Moiety

Drug Research ◽  
2018 ◽  
Vol 69 (08) ◽  
pp. 445-450 ◽  
Author(s):  
Sachin Saini ◽  
Keyword(s):  
Acute Toxicity ◽  
Spectral Data ◽  
Anticonvulsant Activity ◽  
Thioglycolic Acid ◽  
Aromatic Aldehydes

Abstract2-Amino-5-(3’-indolomethylene)-1, 3 , 4 - oxadiazole (3) undergoes facile condensation with various aromatic aldehydes to gave 2-substitiuted arylidenylamino-5-(3’- indolomethylene) – 1, 3 , 4 – oxadiazole (4–8). Cyclocondensation of (4–8) with thioglycolic acid and triethylamine yielded 3-[5’-(3”- indolomethylene)- 1’, 3’, 4’- oxadiazol-2’-yl]- 2- (substituted aryl)-4- thiazolidinones (9–13) and 1-[5’-(3”- indolomethylene) -1’, 3’, 4’- oxadiazol - 2’- yl ] -4-(substituted aryl) -2- azetidinones (14–18). The structures of these compounds were established on the basis of analytical and spectral data. The newly synthesised compounds were evaluated for their anticonvulsant activity and acute toxicity.

scholarly journals On Regioselectivity of Aldol Condensation of Aromatic Aldehydes with Borate Complex of Acetylacetone

2014 ◽  
Vol 44 (9) ◽  
pp. 1245-1250 ◽  
Author(s):  
Val V. Martichonok ◽  
Peter K. Chiang ◽  
Padraick J. Dornbush ◽  
Kirkwood M. Land
Keyword(s):  
Aldol Condensation ◽  
Aromatic Aldehydes ◽  
Borate Complex

scholarly journals Synthesis and Antibacterial Activity of Chalcones and Pyrimidine-2-ones

2005 ◽  
Vol 2 (2) ◽  
pp. 109-112
Author(s):  
A. K. Parekh ◽  
K. K. Desai
Keyword(s):  
Antibacterial Activity ◽  
Spectral Data ◽  
Elemental Analysis ◽  
Aromatic Aldehydes ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
E Coli ◽  
Gram Positive Bacteria ◽  
H Nmr

Some new chalcones have been prepared by Claisen-schmidt condensation of ketone and different aromatic aldehydes. These chalcones on condensation with urea in presence of acid gave Pyrimidine-2-ones. The synthesized compounds have been characterized by elemental analysis, IR and1H NMR spectral data. They have been screened for their antibacterial activity against Gram positive bacteria B. subtillis & S. aureus and Gram negative bacteria E. coli & S. typhi.

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