Cerium(IV) sulfate catalyzed one-pot three-component diastereo selective synthesis of 4-amidotetrahydropyrans
Keyword(s):
One Pot
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A convenient and diastereoselective one-pot synthesis of cis-4-amidotetrahydropyrans is described. This simple protocol involves Prins cyclization of homoallylic alcohol and aldehydes, followed by Ritter reaction of acetonitrile leading to the formation of cis-4-acetamidopyrans in good yields.
2010 ◽
Vol 51
(21)
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pp. 2872-2874
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2010 ◽
Vol 51
(21)
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pp. 2813-2819
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