A Fmoc/Boc pseudoisocytosine monomer for peptide nucleic acid synthesis

2008 ◽  
Vol 86 (11) ◽  
pp. 1026-1029 ◽  
Author(s):  
Filip Wojciechowski ◽  
Robert HE Hudson
Keyword(s):  
Nucleic Acid ◽  
Peptide Nucleic Acid ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis

The synthesis of N-[2-(fluorenylmethoxycarbonyl)aminoethyl]-N-[(2-N-(tert-butoxycarbonyl)isocytosin-5-yl)acetyl]glycine peptide nucleic acid monomer is described. The N-tert-butoxycarbonyl protected monomer is compatible with commercially available monomers designed for the Fmoc-oligomerization strategy and is deprotected under mild acidolysis conditions.Key words: PNA, polyamide, pseudoisocytosine, J-base, triplex.

Peptide Nucleic Acid Synthesis by Novel Amide Formation

2007 ◽  
Vol 9 (17) ◽  
pp. 3291-3293 ◽  
Author(s):  
Hyunil Lee ◽  
Jae Hoon Jeon ◽  
Jong Chan Lim ◽  
Hoon Choi ◽  
Yeohong Yoon ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Peptide Nucleic Acid ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis ◽  
Amide Formation

scholarly journals A Peptide & Peptide Nucleic Acid Synthesis Technology for Transporter Molecules and Theranostics - The SPPS

2014 ◽  
Vol 11 (7) ◽  
pp. 697-706 ◽  
Author(s):  
Ruediger Pipkorn ◽  
Klaus Braun ◽  
Manfred Wiessler ◽  
Waldemar Waldeck ◽  
Hans-Hermann Schrenk ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Peptide Nucleic Acid ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis
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