A new microwave-assisted synthetic approach to novel pyrimido[4,5-d]pyrimidines

2007 ◽  
Vol 85 (7-8) ◽  
pp. 491-495 ◽  
Author(s):  
Mazaahir Kidwai ◽  
Priya ◽  
Shweta Rastogi ◽  
Kavita Singhal
Keyword(s):  
Environmentally Benign ◽  
High Yield ◽  
Synthetic Approach ◽  
Microwave Assisted ◽  
Basic Alumina ◽  
Catalysed Reaction ◽  
Solvent Free Conditions ◽  
Catalytic Role ◽  
Mw Irradiation

An environmentally benign approach for the synthesis of novel 7-substituted 5-aryl-1H-pyrimido[4,5-d]pyrimidine-2,4-diones, using mineral supports for their catalytic role and as energy transfer media, is described. The methodology eliminates the usage of solvent during the reaction. The rate enhancement and high yield is attributed to the coupling of solvent-free conditions with microwaves. Further, the role of various supports is studied during the reaction and it is concluded that a MW-assisted basic alumina catalysed reaction is the best in terms of catalysis as well as reaction time and yield.Key words: microwave (MW) irradiation, SBT, pyrimido[4,5-d]pyrimidines, alumina, environmentally benign.

scholarly journals A Facile Solvent Free Synthesis of 3-arylidenechroman-4-ones Using Grinding Technique

2012 ◽  
Vol 9 (3) ◽  
pp. 1251-1256 ◽  
Author(s):  
Suresh Kumar ◽  
Jagdish K. Makrandi
Keyword(s):  
Polyphosphoric Acid ◽  
Cold Water ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Environmentally Benign ◽  
High Yield ◽  
Solvent Free Conditions ◽  
Microwave Irradiations ◽  
Grinding Technique ◽  
Solvent Free Synthesis

An efficient method for the synthesis of 3-arylidenechroman-4-ones has been developed under solvent free conditions using grinding technique. Grinding of variously substituted chroman-4-ones with aromatic aldehydes in presence of anhydrous barium hydroxide at room temperature give 3-arylidenechroman-4-ones in high yield (75-92%). Products are obtained by just acidification of the reaction mixture in ice cold water. Reaction in solid state, with enhanced rate, high selectivity and manipulative simplicity are the attractive features of this environmentally benign protocol. The chroman-4-one derivatives required for the reaction have been obtained by polyphosphoric acid (PPA) catalysed cyclisation of phenoxypropanoic acids under microwave irradiations.

scholarly journals N-methylimidazole mediated synthesis of aryl alkyl ethers under microwave irradiation and solvent free conditions

2015 ◽  
Vol 80 (4) ◽  
pp. 459-464
Author(s):  
Hoorieh Djahaniani ◽  
Laila Aghadadashi-Abhari ◽  
Bita Mohtat
Keyword(s):  
Microwave Irradiation ◽  
Solvent Free ◽  
High Yield ◽  
Phenol Derivatives ◽  
Microwave Assisted ◽  
Novel Approach ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
Alkyl Ethers

Microwave-assisted three-component reaction has been established for the synthesis of aryl alkyl ethers. The reaction was carried out under solvent free conditions in the presence of N-methylimidazole and dialkylacetylenedicarboxylate to furnish a novel approach to O-alkylation of phenol derivatives in high yield

scholarly journals Microwave-assisted intramolecular FriedelCrafts acylation of some aryl aliphatic acids using Gd(OTf)3/ [BMI]BF4 catalytic system

2016 ◽  
Vol 19 (2) ◽  
pp. 64-70
Author(s):  
Phuong Hoang Tran ◽  
Vy Hieu Huynh ◽  
Hai Ngoc Tran ◽  
Thach Ngoc Le
Keyword(s):  
Reaction Time ◽  
Microwave Irradiation ◽  
Mild Condition ◽  
Lewis Acids ◽  
Significant Loss ◽  
Environmentally Benign ◽  
High Yield ◽  
Microwave Assisted ◽  
Metal Triflates ◽  
Pharmaceutical Uses

Intramolecular Friedel–Crafts acylation of aryl acids is a “green” reaction and environmentally benign, generates some valuable intermediated compounds for pharmaceutical uses. In addition, metal triflates under microwave irradiation are efficient catalysts, solving many problems when using traditional Lewis acids. Gd(OTf)3/[BMI]BF4, a good catalyst for the intramolecular Friedel–Crafts acylation under mild condition with high yield, reduced the reaction time and pollution. Furthermore, Gd(OTf)3 in [BMI]BF4 was easily recovered and reused without significant loss of its activity

Microwave-assisted one-pot synthesis of some new furo[2,3-b]quinolines using potassium carbonate under solvent-free conditions

2007 ◽  
Vol 85 (12) ◽  
pp. 1041-1044 ◽  
Author(s):  
M Raghavendra ◽  
Halehatty S. Bhojya Naik ◽  
Bailure S Sherigara
Keyword(s):  
Organic Synthesis ◽  
Potassium Carbonate ◽  
Solvent Free ◽  
High Yield ◽  
One Pot ◽  
Mass Spectral ◽  
H Nmr ◽  
Microwave Assisted ◽  
Solvent Free Conditions ◽  
Microwave Assisted Method

A rapid, solvent-free microwave-assisted method has been developed for the synthesis of novel furo quinolines. The title compounds were achieved by the reaction between corresponding 2-hydroxy-3-formyl-quinolines (1a–1c) with chloroacetamide, ethylchloroacetate, and phenacylbromide in specially designed microwave (MW) oven for organic synthesis in unsealed borosil vessel in presence of potassium carbonate. In this method, isolation is accomplished by just treating the reaction mixture with water, and products were obtained in high yield. Hence, this method was found to be very effective and ecofriendly. The structure of the newly synthesized compounds has been evaluated on the basis of analytical, IR, 1H NMR, and mass spectral data.Key words: furoquinoline, microwave irradiation, potassium carbonate, solvent-free conditions.

A simple and eco-sustainable method for the sulfonylation of amines under microwave-assisted solvent-free conditions

RSC Advances ◽  
2014 ◽  
Vol 4 (31) ◽  
pp. 16027-16032 ◽  
Author(s):  
Salah Lakrout ◽  
Hacène K'tir ◽  
Aïcha Amira ◽  
Malika Berredjem ◽  
Nour-Eddine Aouf
Keyword(s):  
Microwave Irradiation ◽  
Reaction Times ◽  
Solvent Free ◽  
Environmentally Benign ◽  
Microwave Assisted ◽  
Catalyst Free ◽  
Solvent Free Conditions

A new environmentally benign, simple, and efficient protocol for the sulfonylation of amines using microwave irradiation under solvent- & catalyst-free conditions is reported. The corresponding sulfonamides were obtained in excellent yields within short reaction times.

New Insights into the Nature of the Band Gap of CuGeO3 Nanoparticles: Synthesis, Electronic Structure, and Optical and Photocatalytic Properties

2019 ◽  
Author(s):  
Victor Y. Suzuki ◽  
Luís Henrique Cardozo Amorin ◽  
Natália H. de Paula ◽  
Anderson R. Albuquerque ◽  
Julio Ricardo Sambrano ◽  
...  
Keyword(s):  
Electronic Structure ◽  
Band Gap ◽  
Material Design ◽  
Photocatalytic Properties ◽  
Critical Parameters ◽  
Synthetic Approach ◽  
Microwave Assisted ◽  
Theoretical Approaches ◽  
Nanoparticles Synthesis ◽  
First Time

<p>We report, for the first time, new insights into the nature of the band gap of <a>CuGeO<sub>3</sub> </a>(CGO) nanocrystals synthesized from a microwave-assisted hydrothermal method in the presence of citrate. To the best of our knowledge, this synthetic approach has the shortest reaction time and it works at the lowest temperatures reported in the literature for the preparation of these materials. The influence of the surfactant on the structural, electronic, optical, and photocatalytic properties of CGO nanocrystals is discussed by a combination of experimental and theoretical approaches, and that results elucidates the nature of the band gap of synthetized CGO nanocrystals. We believe that this particular strategy is one of the most critical parameters for the development of innovative applications and that result could shed some light on the emerging material design with entirely new properties.</p> <p><b> </b></p>

The Role of Phase Transfer Catalysis in the Microwave-Assisted N-Benzylation of Amides, Imides and N-Heterocycles

2009 ◽  
Vol 6 (7) ◽  
pp. 529-534 ◽  
Author(s):  
Istvan Greiner ◽  
Fanni Sypaseuth ◽  
Alajos Grun ◽  
Eva Karsai ◽  
Gyorgy Keglevich
Keyword(s):  
Phase Transfer Catalysis ◽  
Phase Transfer ◽  
Microwave Assisted
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