Nucleophilic additions of lactam-derived enol triflates to aldehydes mediated by nickel(II) and chromium(II) salts
Enol trifluoromethanesulfonates (triflates) derived from N-protected lactams undergo nickel(II)-chloride- and chromium(II)-chloride-promoted carbonyl additions to aldehydes. The yields of this process range from 42%84%.Key words: nickel(II) chloride, chromium(II) chloride, carbonyl addition, lactam-derived enol triflate.
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1970 ◽
Vol 19
(2)
◽
pp. 181-187
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1970 ◽
Vol 19
(1)
◽
pp. 50-53
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