RESISTIVITY OF DEFORMED CRYSTALS

1967 ◽  
Vol 45 (2) ◽  
pp. 1161-1176 ◽  
Author(s):  
Z. S. Basinski ◽  
S. Saimoto

The variation of electrical resistivity with deformation, as a function of purity and orientation, has been studied for Cu single crystals deformed in tension and fatigue. In stage I the rate of increase of resistivity depends very strongly on the impurity content, decreasing with increasing purity. In stage II the resistivity increases quadratically with stress, the rate of increase depending on orientation. The resistivity produced by dislocations appears not to be strongly anisotropic. The value of resistivity per unit dislocation is about 1 × 10−19 ΩSi-cm.

1964 ◽  
Vol 42 (10) ◽  
pp. 1890-1901 ◽  
Author(s):  
M. L. Swanson

The isochronal recovery of deformed polycrystalline Al was measured from 4 to 300 °K by means of residual electrical resistivity measurements. A well-defined recovery stage was observed between 60 and 100 °K (stage IIA); it has also been observed after neutron irradiation, but not after electron irradiation (Sosin 1963). This stage was enhanced by increasing the deformation or introducing quenched-in vacancies, and was suppressed by impurity atoms. These results can be explained by di-interstitial migration. The recovery below 60 °K (stage I) amounted to approximately 5%, and was independent of impurity content or degree of deformation. Both stage I and stage IIA recovery were greatly increased by a prior deformation and low-temperature anneal. A similar increase was observed for Au. This enhancement was attributed to a change in deformation mechanism because of dislocation pinning, which resulted in the formation of a preponderance of interstitial defects.


2007 ◽  
Vol 539-543 ◽  
pp. 3030-3035
Author(s):  
Takashi Matsuo

Through the analysis of many creep rate-strain curves of γ-single phase Ni-20mass%Cr alloy single crystals with various stress axes, it has been elucidated that the ratio of transient stage to rupture life becomes larger with decreasing the stress. And the transient stage consists of Stage I and Stage II. In Stage I, the creep rate just after loading remains constant, and in Stage II, a steep decrease in creep rate continues. It is noticeable that there is a marked difference in transient stage among single crystals with different stress axes. The aim of this study is to elucidate the mechanisms leading to the different transient stages as the function of stress axes. The deformation during transient stage in the single crystals except for the single crystals with the stress axes of the [001] and [1,–11] poles in the standard stereographic triangle, proceeds using the primary slip plane. And they are divided into two groups of the single crystals with the angle between stress axis and primary slip plane, θ, less than 45° and the single crystals with θ more than 45°. The deformations of Stage I and Stage II in these single crystals proceed using the slip system of (111)<1,–01> and the slip system of (111)<1,–10>, and in Stage I, the former slip system acts mainly except for that of single crystals with stress axis of [011]. While, in the single crystal with stress axis of [011], two slip systems above described operate at the beginning of Stage I, and the stress axis moves along [011]-[1,–11] line. And this moving gives slight increase in the Schmid factor, therefore, in Stage I slight increase in creep rate was confirmed. The {111} pole figure of the single crystal with stress axis of [1,–11] whose deformation proceeds using the plural slip planes are obtained by SEM-EBSD method. It becomes clear that the smallest strains of Stage I and Stage II derived from the increase in the torsion with creep deformation.


2006 ◽  
Vol 15-17 ◽  
pp. 870-875 ◽  
Author(s):  
Masaomi Mitsutake ◽  
Yoshihiro Terada ◽  
Takashi Matsuo

The features of the creep deformation of γ-single phase single crystals with the composition of Ni-20mass%Cr are characterized by the extended transient stage, which consists of Stage I and Stage II. In the Stage I, the creep rate just after loading remains unchanged, while the creep rate decreases continuously in Stage II. In the single crystals except for the single crystals with the stress axis of [001] and [1, – 11], the predominant creep deformation using the primary slip plane continues. By this deformation, the cross section of specimen turns to elliptical in shape. However, in the single crystals with the angle between stress axis and primary slip plane (111) is more than 45°, the deformation using the primary slip plane does not continue, as a result, the duration of Stage II turn to shorter one. The single crystal with the stress axis of [011] has the largest angle of 55°. In this study, the deformation manner during transient stage of single crystal with the stress axis of [011] orientation is investigated from the two viewpoints. The first one is to clarify the change in deformation manner with decreasing the stress. As a result, with decreasing the stress, the Stage I become clear and strain during Stage I and Stage II become small, furthermore, the decreasing ratio of creep rate with definite strain becomes larger. While, the second viewpoint is to investigate the change in crystallographic orientation of the [011] single crystals with creep deformation using the inverse pole figure obtained by the EBSD method. As a result, at the stress of 29.4 MPa, the spot of stress axis turns from the [011]-[1, – 11] line to the <1, – 01> direction. While, at the stress of 19.6 MPa, the stress axis moves for the [1, – 11] pole along the [011]-[1, – 11] line from the [011] pole. And, it is noteworthy that the spot widely spread from the [011] pole during transient stage. This indicates the large distortion in the primary slip plane and the evidence of heterogeneous deformation.


Author(s):  
H. P. Karnthaler ◽  
A. Korner

In f.c.c. metals slip is observed to occur generally on {111} planes. Glide dislocations on intersecting {111} planes can react with each other and form Lomer-Cottrell locks which lie along a <110> direction and are sessile since they are split on two {111} planes. Cottrell already pointed out that these dislocations could glide on {001} planes if they were not split. The first study of this phenomenon has been published recently. It is the purpose of this paper to report some interesting new details of the dislocations gliding on {001} planes in pure Ni, Cu, and Ag deformed at room temperature.Single crystals are grown with standard orientation and strained into stage II. The crystals are sliced parallel to the (001) planes. The dislocation structure is studied by TEM and the Burgers vectors ḇ and glide planes of the dislocations are determined unambiguously.In Fig.l primary P and secondary S dislocations react and form composite dislocations K.


2020 ◽  
Vol 15 ◽  
Author(s):  
Athira K ◽  
Vrinda C ◽  
Sunil Kumar P V ◽  
Gopakumar G

Background: Breast cancer is the most common cancer in women across the world, with high incidence and mortality rates. Being a heterogeneous disease, gene expression profiling based analysis plays a significant role in understanding breast cancer. Since expression patterns of patients belonging to the same stage of breast cancer vary considerably, an integrated stage-wise analysis involving multiple samples is expected to give more comprehensive results and understanding of breast cancer. Objective: The objective of this study is to detect functionally significant modules from gene co-expression network of cancerous tissues and to extract prognostic genes related to multiple stages of breast cancer. Methods: To achieve this, a multiplex framework is modelled to map the multiple stages of breast cancer, which is followed by a modularity optimization method to identify functional modules from it. These functional modules are found to enrich many Gene Ontology terms significantly that are associated with cancer. Result and Discussion: predictive biomarkers are identified based on differential expression analysis of multiple stages of breast cancer. Conclusion: Our analysis identified 13 stage-I specific genes, 12 stage-II specific genes, and 42 stage-III specific genes that are significantly regulated and could be promising targets of breast cancer therapy. That apart, we could identify 29, 18 and 26 lncRNAs specific to stage I, stage II and stage III respectively.


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
P Milani ◽  
L Obici ◽  
R Mussinelli ◽  
M Basset ◽  
G Manfrinato ◽  
...  

Abstract Background Cardiac wild type transthyretin (ATTRwt) amyloidosis, formerly known as senile systemic amyloidosis, is an increasingly recognized, progressive, and fatal cardiomyopathy. Two biomarkers staging systems were proposed based on NT-proBNP (in both cases) and troponin or estimated glomerular filtration rate, that are able to predict survival in this population. The availability of novel effective treatments requires large studies to describe the natural history of the disease in different populations. Objective To describe the natural history of the disease in a large, prospective, national series. Methods Starting in 2007, we protocolized data collection in all the patients diagnosed at our center (n=400 up to 7/2019). Results The referrals to our center increased over time: 5 cases (1%) between 2007–2009, 33 (9%) in 2010–2012, 90 (22%) in 2013–2015 and 272 (68%) in 2016–2019. Median age was 76 years [interquartile range (IQR): 71–80 years] and 372 patients (93%) were males. One hundred and seventy-three (43%) had atrial fibrillation, 63 (15%) had a history of ischemic cardiomyopathy and 64 (15%) underwent pacemaker or ICD implantation. NYHA class was I in 58 subjects (16%), II in 225 (63%) and III in 74 (21%). Median NT-proBNP was 3064 ng/L (IQR: 1817–5579 ng/L), troponin I 0.096 ng/mL (IQR: 0.063–0.158 ng/mL), eGFR 62 mL/min (IQR: 50–78 mL/min). Median IVS was 17 mm (IQR: 15–19 mm), PW 16 mm (IQR: 14–18 mm) and EF 53% (IQR: 45–57%). One-hundred and forty-eight subjects (37%) had a concomitant monoclonal component in serum and/or urine and/or an abnormal free light chain ratio. In these patients, the diagnosis was confirmed by immunoelectron microscopy or mass spectrometry. In 252 (63%) the diagnosis was based on bone scintigraphy. DNA analysis for amyloidogenic mutations in transthyretin and apolipoprotein A-I genes was negative in all subjects. The median survival of the whole cohort was 59 months. The Mayo Clinic staging based on NT-proBNP (cutoff: 3000 ng/L) and troponin I (cutoff: 0.1 ng/mL) discriminated 3 different groups [stage I: 131 (35%), stage II: 123 (32%) and stage III: 127 (33%)] with different survival between stage I and II (median 86 vs. 81 months, P=0.04) and between stage II and III (median 81 vs. 62 months, P&lt;0.001). The UK staging system (NT-proBNP 3000 ng/L and eGFR 45 mL/min), discriminated three groups [stage I: 170 (45%), stage II: 165 (43%) and stage III: 45 (12%)] with a significant difference in survival: between stage I and stage II (86 vs. 52 months, P&lt;0.001) and between stage II and stage III (median survival 52 vs. 33 months, P=0.045). Conclusions This is one of the largest series of patients with cardiac ATTRwt reported so far. Referrals and diagnoses increased exponentially in recent years, One-third of patients has a concomitant monoclonal gammopathy and needed tissue typing. Both the current staging systems offered good discrimination of staging and were validated in our independent cohort. Funding Acknowledgement Type of funding source: None


2021 ◽  
Vol 8 ◽  
pp. 2333794X2110104
Author(s):  
Débora de Fátima Camillo Ribeiro ◽  
Frieda Saicla Barros ◽  
Beatriz Luci Fernandes ◽  
Adriane Muller Nakato ◽  
Percy Nohama

Short binasal prongs can cause skin and mucosal damage in the nostrils of preterm infants. The objective of this study was to investigate the incidence and severity of nasal injuries in preterm infants during the use of short binasal prongs as non-invasive ventilation (NIV) interfaces. A prospective observational study was carried out in the public hospital in a Southern Brazil. The incidence and severity of internal and external nasal injuries were evaluated in 28 preterm infants who required NIV using short binasal prongs for more than 24 hours. In order to identify possible causes of those nasal injuries, the expertise researcher physiotherapist has been carried empirical observations, analyzed the collected data, and correlated them to the literature data. A cause and effect diagram was prepared to present the main causes of the nasal injury occurred in the preterm infants assessed. The incidence of external nasal injuries was 67.86%, and internal ones 71.43%. The external nasal injuries were classified as Stage I (68.42%) and Stage II (31.58%). All the internal injuries had Stage II. The cause and effect diagram was organized into 5 categories containing 17 secondary causes of nasal injuries. There was a high incidence of Stage II-internal nasal injury and Stage I-external nasal injury in preterm infants submitted to NIV using prongs. The injuries genesis can be related to intrinsic characteristics of materials, health care, neonatal conditions, professional competence, and equipment issues.


2021 ◽  
Vol 11 (11) ◽  
pp. 5281
Author(s):  
Marcin Spychała ◽  
Tadeusz Nawrot ◽  
Radosław Matz

The aim of the study was to verify two morphological forms (“angel hair” and “scraps”) of xylit as a trickling filter material. The study was carried out on two types of polluted media: septic tank effluent (STE) and seminatural greywater (GW). The basic wastewater quality indicators, namely, chemical oxygen demand (COD), biochemical oxygen demand (BOD5), total suspended solids (TSS), ammonium nitrogen (NNH4), and total phosphorus (Ptot) were used as the indicators of treatment efficiency. Filtering columns filled with the investigated material acted as conventional trickling filters at a hydraulic load of 376–472 cm3/d during the preliminary stage, 198–245 cm3/d during stage I, and 184–223 cm3/d during stage II. The removal efficiency of the two morphological forms of xylit did not differ significantly. The average efficiencies of treatment were as follows: for COD, over 70, 80, and 85% for preliminary stage, stage I and stage II, respectively; for BOD5, 77–79% (preliminary stage); for TSS, 42% and 70% during the preliminary stage, and 88, 91, and 65% during stage I; for NNH4, 97–99% for stage I and 36–49% for stage II; for Ptot, 51–54% for stage I and 52–56% for stage II. The study demonstrated that xylit was a material highly effective in wastewater quality indicators removal, even during the initial period of its use.


2020 ◽  
Vol 28 (1) ◽  
pp. 138-151
Author(s):  
Kelly A. Stahl ◽  
Elizabeth J. Olecki ◽  
Matthew E. Dixon ◽  
June S. Peng ◽  
Madeline B. Torres ◽  
...  

Gastric cancer is the third most common cause of cancer deaths worldwide. Despite evidence-based recommendation for treatment, the current treatment patterns for all stages of gastric cancer remain largely unexplored. This study investigates trends in the treatments and survival of gastric cancer. The National Cancer Database was used to identify gastric adenocarcinoma patients from 2004–2016. Chi-square tests were used to examine subgroup differences between disease stages: Stage I, II/III and IV. Multivariate analyses identified factors associated with the receipt of guideline concordant care. The Kaplan–Meier method was used to assess three-year overall survival. The final cohort included 108,150 patients: 23,584 Stage I, 40,216 Stage II/III, and 44,350 Stage IV. Stage specific guideline concordant care was received in only 73% of patients with Stage I disease and 51% of patients with Stage II/III disease. Patients who received guideline consistent care had significantly improved survival compared to those who did not. Overall, we found only moderate improvement in guideline adherence and three-year overall survival during the 13-year study time period. This study showed underutilization of stage specific guideline concordant care for stage I and II/III disease.


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