THE PLASMA 17-HYDROXYCORTICOSTEROID LEVELS IN ACUTE AND CHRONIC RENAL FAILURE

1961 ◽  
Vol 39 (10) ◽  
pp. 1617-1624 ◽  
Author(s):  
A. J. Blair ◽  
R. O. Morgen ◽  
J. C. Beck
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
Chronic Renal Disease

The free and glucuronide fractions of the plasma 17-hydroxycorticosteroids have been determined on specimens from 14 adult controls, 7 patients with chronic renal disease, and 11 patients with acute renal failure. The results have been statistically analyzed. Both free and glucuronide fractions were shown to be elevated in cases of acute renal failure while neither was significantly altered in the cases of chronic renal disease. The changes in these fractions during diuresis and hemodialysis in a few cases of acute renal failure are also reported. The possible mechanisms for these findings are briefly discussed.

scholarly journals Chronic Renal Failure, Cachexia, and Ghrelin

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
A. Laviano ◽  
Z. Krznaric ◽  
K. Sanchez-Lara ◽  
I. Preziosa ◽  
A. Cascino ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Food Intake ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Contributing Factors ◽  
Protein Energy Wasting ◽  
Protein Energy ◽  
Stage Renal Disease ◽  
End Stage

Protein energy wasting is frequently observed in patients with advanced chronic renal failure and end-stage renal disease. Anorexia and reduced food intake are critical contributing factors and negatively impact on patients' survival. Ghrelin is a prophagic peptide produced by the stomach and acting at the hypothalamic level to increase the activity of orexigenic neurons. In patients with chronic renal disease, plasma levels are increased as a likely effect of reduced renal clearance. Nevertheless, patients' food intake is significantly reduced, suggesting inflammation-mediated resistance of hypothalamic nuclei to peripheral signals. A number of forms of evidence show that ghrelin resistance could be overcome by the administration of exogenous ghrelin. Therefore, ghrelin has been proposed as a potential strategy to improve food intake in chronic renal failure patients with protein energy wasting. Preliminary data are encouraging although larger prospective clinical trials are needed to confirm the results and to identify those patients who are likely to benefit most from the administration of exogenous ghrelin.

scholarly journals HAEMODIALYSIS IN B. P. KOIRALA INSTITUTE OF HEALTH SCIENCES, DHARAN - AN INITIAL EXPERIENCE

2003 ◽  
Vol 40 (139) ◽  
pp. 134-138 ◽  
Author(s):  
Sanjib Kumar Sharma ◽  
P Kumar ◽  
A Chapagain ◽  
S Koirala
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Community Education ◽  
Health Sciences ◽  
Renal Diseases ◽  
Stage Renal Disease ◽  
End Stage

Dialysis supports life, in spite of complete cessation of renal functions. Haemodialysis(HD) service became available in B. P. Koirala Institute of Health Sciences, Dharansince September 1999. Six hundred and sixty one sessions of HD in 50 patients werecarried out in one year. End stage renal disease (ESRD), acute renal failure (ARF),acute on chronic renal failure constituted 54%, 26% and 20% of the patientsrespectively. Majority of the patients (72%) were between 15 to 50 years of age. Chronicglomerulonephritis, chronic interstitial nephritis, and diabetes nephropathy were themost common causes of ESRD. Recovery following HD was 70% in ARF,whileallpatients of acute on chronic renal failure improved following few sessions of HD.Drop out rate on maintained haemodialysis (MHD) was 52%. The increasing demandof dialysis service in this region is difficult to fulfill due to restricted facilities fordialysis, lack of renal transplantation in Nepal, and economic constraint in the part ofpatients. Primary and secondary prevention of renal diseases by community education,awareness and participation needs emphasis. Key Words: Haemodialysis, End stage renal disease, Acute renal failure,Acute on chronic renal failure.

scholarly journals Incidence of cutaneous manifestation in patients with end stage renal disease

2017 ◽  
Vol 4 (4) ◽  
pp. 989
Author(s):  
Khileshwar Singh ◽  
Amit Thakur ◽  
Kamlesh Dhruv
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Cutaneous Manifestation ◽  
Renal Diseases ◽  
Cutaneous Manifestations ◽  
Stage Renal Disease ◽  
End Stage

Background: Kidney failure as well as renal diseases is the most important health problems affecting the middle and old age population all over the world. They were supposed to be fatal till recently. The objective of this study was to study incidence of cutaneous manifestation in patients with end stage renal disease.Methods: A hospital based cross sectional study was carried out from July 2012 to June 2013 in the Department of General Medicine, Late Baliram Kashyap Memorial Government Medical College, Jagdalpur, Chhattisgarh, India. It was possible to study a total of 50 cases of cutaneous manifestations that are already known cases of end stage renal disease. All patients with skin lesion were evaluated by history, clinical examination (systemic and dermatological), biopsy and other relevant investigations procedure for skin disease during the course of current renal disease and their stay in the hospital.Results: The incidence of cutaneous manifestations among patients with acute renal failure was zero. It was 86% among patients with chronic renal failure. The most common manifestation was pruritus in 14% of cases followed by oral candidiasis in 4% of cases. Next common was scabies in 6% of cases and this was followed by herpes zoster and Tinea cruris in 4% of cases each. Folliculitis was seen in only one case. It was seen that all types of cutaneous manifestations were present only in patients with chronic renal failure, whereas patients of acute renal failure did not show any sort of cutaneous manifestations.Conclusions: Chronic renal failure was observed as the important cause of cutaneous manifestations seen in patients with end stage renal disease. No cases were seen in patients with acute renal failure. Thus, it is important that patients with acute renal failure take proper precautions to avoid cutaneous manifestations up to the extent possible.

Dietary Assessment of Patients Suffering From Chronic Renal Failure With Complications

2020 ◽  
pp. 46-50
Author(s):  
OJS Admin
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
Glomerular Filtration ◽  
Chronic Renal Disease ◽  
Dietary Assessment ◽  
Clinical Manifestations ◽  
Major Health ◽  
Day By Day ◽  
Major Health Issue

Chronic renal disease is generally referred as impaired functioning of kidneys. Occurrence of kidney damage, increased loss of albumin in urine and a decreased glomerular filtration (GFR) rate are the clinical manifestations of chronic renal disease. It is a major health issue worldwide and the rate of this disease is increasing day by day.

Iron Absorption in Chronic Renal Disease

1970 ◽  
Vol 38 (2) ◽  
pp. 191-196 ◽  
Author(s):  
J. W. Eschbach ◽  
J. D. Cook ◽  
C. A. Finch
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
Iron Overload ◽  
Iron Absorption ◽  
Chronic Renal Disease ◽  
Iron Depletion ◽  
Isotope Technique ◽  
Double Isotope

1. Absorption of inorganic iron was studied in thirty-four patients with chronic renal failure by a double isotope technique. 2. Eight patients with normal iron balance had a mean absorption of 3·5%, ten patients with iron overload had a mean absorption of 3·6%, and sixteen patients with iron depletion had a mean absorption of 58%. Thus, alterations in absorption appeared to be related to disturbances in iron balance. 3. The rate of erythropoiesis had no evident effect on iron absorption nor did the degree of anaemia. 4. The presence of renal disease and the degree of azotaemia likewise did not appear to affect absorption.

scholarly journals Systemic conditions, oral findings and dental management of chronic renal failure patients: general considerations and case report

2006 ◽  
Vol 17 (2) ◽  
pp. 166-170 ◽  
Author(s):  
Mahmud Juma Abdalla Abdel Hamid ◽  
Claus Dieter Dummer ◽  
Lourenço Schmidt Pinto
Keyword(s):  
Renal Failure ◽  
Case Report ◽  
Chronic Renal Failure ◽  
Periodontal Disease ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Systemic Disease ◽  
Frequent Occurrence ◽  
Oral Manifestations ◽  
Dental Management

Chronic renal failure is a relatively common systemic disease. Systemic abnormalities such as anemia, platelet disorders and hypertension as well as oral manifestations including xerostomia, uremic stomatitis, periodontal disease and maxillary and mandibular radiographic alterations can be observed in individuals with chronic renal disease. In view of its frequent occurrence and the need of knowledge by dentists dealing with this condition, this paper discusses the most important issues regarding chronic renal failure, addressing its systemic and oral manifestations and the dental management of chronic renal patients. A case report is presented.

Coagulation Factor XIII and Serum Triglycerides in Patients with Chronic Renal Disease on Conservative and Regular Dialysis Treatment

1979 ◽  
Author(s):  
F. Carmassi ◽  
G. Mariani ◽  
R. Palla ◽  
L. Fusani ◽  
R. Dianchi
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
Factor Xiii ◽  
Chronic Renal Disease ◽  
Coagulation Factor ◽  
Chronic Hemodialysis ◽  
Serum Triglycerides ◽  
Coagulation Factor Xiii ◽  
Regular Dialysis Treatment

The behaviour of coagulation factor XIII (fibrin stabilizing factor, FSF) and of serum triglycerides was studied in patients with chronic renal disease, using a specific antiserum to the active subunit (FSFA) for the direct measurement of the active fraction according to the Laurell’s method. The plasma FSFA concentration was measured in the following patients: I) 31 patients with chronic renal disease and serum creatinine below 1.5 mg/dl; II) 41 patients with chronic renal failure on conservative treatment; III) 53 chronic uremic patients on regular hemodialysis. FSFA concentration was significantly higher than normal (P<0.005) in the patients with chronic renal disease without renal failure, and similarly increased in the 41 patients with chronic renal failure on conservative therapy (P<0.001), as well as in the patients on chronic hemodialysis (P<0.001). Plasma FSFA levels were significantly higher in those patients with serum triglycerides above the upper normal limit and a significant positive correlation was found between serum triglycerides and FSFA plasma levels. These findings suggest a possible interaction of FSF with blood VLDLs in the genesis of atherosclerosis, early and severe complication of uremia.

Acute Renal Failure in the Presence of Chronic Renal Disease in a 31-Year-Old Caucasian Female

2008 ◽  
Vol 39 (9) ◽  
pp. 533-535 ◽  
Author(s):  
Felix O. Omoruyi ◽  
Anthony O. Okorodudu ◽  
Amin A. Mohammad ◽  
John R. Petersen
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Caucasian Female
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