SOME EFFECTS OF DIETARY THIOURACIL AND DIETARY IODINE SUPPLEMENTATION ON THE RESPONSES OF THE IMMATURE PULLET TO ESTROGEN

1961 ◽  
Vol 39 (9) ◽  
pp. 1441-1450
Author(s):  
R. H. Common ◽  
A. J. Moo-Young ◽  
K. A. McCully

Sexually immature pullets were given 1.5 mg estradiol benzoate by intramuscular injection on alternate days over a 14-day period. The resultant increase of oviduct weight was enhanced by 70% when 1% thiouracil was included in the diet over the period of the injections. Supplementation of the diet with 1.0 mg iodine per lb did not modify this effect of dietary thiouracil on the response of oviduct to estrogen. Consideration of this result in conjunction with previous results shows that a necessary condition for this positive effect of thiouracil on response of the oviduct to estrogen is administration of the estrogen on alternate days.The following effects of thiouracil on the estrogenized pullets also attained statistical significance: decrease of estrogen-induced hypercalcemia; increase of ovary weight, liver weight, and total liver crude protein and fat; increase of kidney weight and percentage dry matter in kidney.The iodine supplement increased ovary weight significantly in the unestrogenized pullets but not in the estrogenized pullets. The iodine supplement also tended to increase total liver crude protein in the estrogenized pullets but not in the unestrogenized pullets.

1958 ◽  
Vol 36 (1) ◽  
pp. 1023-1035
Author(s):  
R. H. Common ◽  
W. A. Maw ◽  
D. S. Layne ◽  
K. A. McCully

Thiouracil was given to sexually immature pullets at a level of 0.05% of the diet for 14 days before and also during treatment with 0.5 mg estradiol benzoate (ODB) or 1.0 mg ODB daily for 14 days. The thiouracil treatment did not modify the estrogen-induced hypercalcemia after 7 days, but after 14 days it enhanced significantly the blood calcium response to 1.0 mg ODB per day. The positive effects of thiouracil and of estrogen on liver weight per kg live weight were significant and additive. The comparatively low level of thiouracil used did not increase liver fat per kg live weight significantly, but it increased significantly the positive effect of estrogen on liver fat. The thiouracil treatment had no significant effect on liver deoxyribonucleic acid phosphorus (DNAP) but it increased liver pentose nucleic acid phosphorus (RNAP) per kg live weight significantly both in absence and presence of estrogen. The thiouracil treatment had no effect on the responses of the oviduct to estrogen.In a second experiment the effects of (a) 1.0% thiouracil for 10 days before and also during a 14-day estrogen treatment of 1.0 mg ODB per day and of (b) 1.0% thiouracil given concurrently with 1.0 mg ODB per day were studied. Neither thiouracil treatment affected the response of the oviduct to estrogen. The other results confirmed previous observations.In a third experiment, 1.5 mg ODB was given every other day for 14 days. When thiouracil at a level of 1% was given concurrently with the estrogen, it enhanced significantly the response of the oviduct. When 1% thiouracil was given also for 10 days before the estrogen, then it did not enhance the response of the oviduct. This experiment suggests that the conditions under which thiouracil will enhance estrogen-induced hypertrophy of the oviduct are narrowly defined. Other results were in general agreement with previous observations.


1958 ◽  
Vol 36 (10) ◽  
pp. 1023-1035
Author(s):  
R. H. Common ◽  
W. A. Maw ◽  
D. S. Layne ◽  
K. A. McCully

Thiouracil was given to sexually immature pullets at a level of 0.05% of the diet for 14 days before and also during treatment with 0.5 mg estradiol benzoate (ODB) or 1.0 mg ODB daily for 14 days. The thiouracil treatment did not modify the estrogen-induced hypercalcemia after 7 days, but after 14 days it enhanced significantly the blood calcium response to 1.0 mg ODB per day. The positive effects of thiouracil and of estrogen on liver weight per kg live weight were significant and additive. The comparatively low level of thiouracil used did not increase liver fat per kg live weight significantly, but it increased significantly the positive effect of estrogen on liver fat. The thiouracil treatment had no significant effect on liver deoxyribonucleic acid phosphorus (DNAP) but it increased liver pentose nucleic acid phosphorus (RNAP) per kg live weight significantly both in absence and presence of estrogen. The thiouracil treatment had no effect on the responses of the oviduct to estrogen.In a second experiment the effects of (a) 1.0% thiouracil for 10 days before and also during a 14-day estrogen treatment of 1.0 mg ODB per day and of (b) 1.0% thiouracil given concurrently with 1.0 mg ODB per day were studied. Neither thiouracil treatment affected the response of the oviduct to estrogen. The other results confirmed previous observations.In a third experiment, 1.5 mg ODB was given every other day for 14 days. When thiouracil at a level of 1% was given concurrently with the estrogen, it enhanced significantly the response of the oviduct. When 1% thiouracil was given also for 10 days before the estrogen, then it did not enhance the response of the oviduct. This experiment suggests that the conditions under which thiouracil will enhance estrogen-induced hypertrophy of the oviduct are narrowly defined. Other results were in general agreement with previous observations.


1960 ◽  
Vol 40 (2) ◽  
pp. 119-125 ◽  
Author(s):  
A. J. Moo-Young ◽  
K. A. McCully ◽  
R. H. Common

Inclusion of 0.5 per cent desiccated thyroid in the food of unestrogenized immature pullets for 14 days reduced thyroid weight, reduced serum Ca slightly but significantly, increased liver total crude protein, liver total DNAP and total RNAP, but did not alter the ratio RNAP:DNAP in the liver. These results are regarded as indicative of stimulation of growth of liver tissues by the thyroidal treatment.Daily intramuscular, injection of 1.0 mg. estradiol benzoate for 14 days greatly increased serum Ca and liver total crude protein, increased slightly liver total DNAP and increased greatly liver total RNAP and ratio RNAP: DNAP in the liver. The thyroidal treatment reduced estrogen-induced increase of serum Ca and of liver crude protein but did not alter significantly the effects of estrogen on liver DNAP and RNAP.The thyroidal treatment increased kidney weight in both unestrogenized and estrogenized pullets.Estrogen treatment increased kidney weight and the percentage of dry matter in the kidney.The thyroidal treatment did not affect the degree of estrogen-induced hypertrophy of the oviduct.


1989 ◽  
Vol 112 (1) ◽  
pp. 57-66 ◽  
Author(s):  
N. Moreira

SummaryExperiments were conducted on the seed rates of the components of oat-vetch mixtures combined with varying rates of nitrogen fertilizer in a rainfed area of north-east Portugal in 1982–3 and 1984–5.Forage oats grown alone showed a very high yield response to N and rainfall ranging from 30 to 18·2 t D.M./ha, but had a very low crude protein concentration (37–54 g/kg D.M.) and a poor mineral nutrient composition.The increased use of vetch in the seed mixture had a buffering effect on dry-matter (D.M.) yield but this depended very much on crop N nutrition. For N-deficient conditions vetch inclusion increased the D.M. yield and had a strong positive effect on total forage crude protein (CP) and mineral composition. When crop N nutrition was good, very high D.M. yields (> 12 t D.M./ha) were possible using a high proportion of oats, with vetch making a reduced contribution to the yield and nutritive value of total forage.Seed rates suggested in the literature for Mediterranean conditions are adequate for low N inputs and low available soil N, but not for high D.M. yields which can only be obtained by using a higher proportion of oats and adequate N fertilizer.


2013 ◽  
Vol 17 (2) ◽  
pp. 121-127
Author(s):  
Luboš Zábranský ◽  
Miloslav Šoch ◽  
Pavel Novák ◽  
Jan Brouček ◽  
Anna Šimková ◽  
...  

Abstract the aim of our study was to evaluate influence of probiotic agents (Lactovita) and seaweed extracts (Biopolym) with antidiarrheal effects on the prevention of diarrhoea in calves. In the experiment 22 experimental and 22 control calves were observed. The results of the observed incidence of diarrhoea in the control and experimental groups showed a positive effect of probiotic Lactovita and seaweed extracts Biopolymer. 32% of calves in the experimental group and 45% of calves in the control group became sick. Unfortunately, we could not demonstrate the statistical significance of these differences. The weight gains found in the 4th week after birth were by 37.6% higher in the group with Lactovita and Biopolym than in the control group.


2008 ◽  
Vol 53 (No. 2) ◽  
pp. 77-82 ◽  
Author(s):  
M. Lichovníková ◽  
L. Zeman ◽  
J. Jandásek

The objective of the experiment was to evaluate the effect of the feeding of 80 g/kg (R8) and 100 g/kg (R10) of untreated rapeseed (RS) on egg quality including sensory quality in comparison with a control diet without rapeseed (R0). The addition of iodine (I) was also evaluated (1 mg/kg (R10) vs. 3 mg/kg (R10+I)). “Double zero” RS was used. The contents of energy and crude protein were almost the same in the diets. Laying hybrid ISABROWN was used in the experiment. The quality of eggs was analyzed 11 times every 28 days, from 19 to 64 weeks of age. 30 eggs per each group were always analyzed. Boiled eggs were assessed twice around the peak of egg production. Egg weight decreased (<I>P</I> < 0.001) with the increased level of RS (62.9 g, 61.8 g and 60.7 g, respectively). A reduction in egg weight in R8 and R10 diets resulted in the lower weight of albumen and eggshells. The addition of I to R10 diet increased (<I>P</I> < 0.001) egg weight (62.1 g vs. 60.7 g). The yolk proportion in egg weight was the highest (26.0%, <I>P</I> < 0.001) and the albumen weight ratio was the lowest (64.2%, <I>P</I> < 0.001) in group R8. Iodine supplementation improved (<I>P</I> < 0.001) yolk weight (15.7 g vs. 15.3 g). The proportion of RS in the diet did not affect the eggshell strength. An increase in the level of I improved (<I>P</I> < 0.001) eggshell quality (strength 36.1 N vs. 34.0 N and thickness 0.386 mm vs. 0.363 mm). Taste and overall acceptability were lower (<I>P</I> < 0.05) in eggs of hens fed RS. The addition of I did not affect flavour, odour, taste or overall acceptability.


2018 ◽  
Vol 9 (1) ◽  
pp. 37-60
Author(s):  
Osman Basit ◽  
Esra Ömeroğlu

This research was carried out with the aim of examining the impact of communication training based on ‘from the child to mother approach’ on the communication of the mothers with their children attending mobile preschools. The sample comprised 80 children attending mobile preschool and mothers of those children. Two of the five neighborhoods served by the mobile preschool were designated randomly as experiment groups and the remaining as control groups. There were 33 children and mothers in the experimental group and 47 in the control group. The data was collected by General Information Form and Parent-Child Communication Evaluation Tool. During the course of the research, the Communication Training Program prepared by the researcher and based on the Child to Mother Approach was applied to the experimental group for two days in a week during eight weeks. In order to examine the impact of Communication Training Program on mother-child communication, t-test was conducted for both the independent group and the dependent group. Statistical significance was set at .05. As a result of the analyses, it has been determined that the Communication Training Program has a positive effect on communication between mothers and children and this effect is permanent. In line with the results of the research, suggestions for preschool education teachers, parents and researchers are presented.


2021 ◽  
Vol 52 (4) ◽  
pp. 294-298
Author(s):  
Tatjana Erceg-Rukavina ◽  
Dragana Dragičević-Cvjetković

Background/Aim: The positive effect of thermal mineral waters on human health has been known for a long time. Many pathophysiological mechanisms of action of balneotherapy are not specified. Patients with gonarthrosis often have elevated values of serum lipids. This study aimed to examine the effect of drinking sulphate-sulphide thermo mineral water on the lipid status of patients with gonarthrosis. Methods: A prospective clinical study followed 60 patients, both sexes, mean age 65.02 ± 1.03, with gonarthrosis. All inpatient underwent physical treatment with topical application of sulphate-sulphide mineral water. Patients of group A (N = 30) had the use of this mineral water as an additional therapy by drinking, unlike patients of group B (N = 30) who drank plain water. The level of serum lipids of these patients was monitored at admission and 4 weeks after. The variance analysis test (ANOVA) with a level of statistical significance p < 0.001 was used for statistical analysis. Results: A significant reduction in the levels of all lipid fractions in the serum of patients with gonarthrosis was found 4 weeks after the completion of inpatient physical treatment in both study groups. This decrease was statistically significant in patients of group A (p < 0.001). Conclusion: Drinking sulphate-sulphide mineral water in patients with gonarthrosis shows a positive effect on the reduction of serum lipid levels in the short-term follow-up period.


2021 ◽  
Vol 25 (1) ◽  
pp. 17-21
Author(s):  
A. O. FANIMO ◽  
O. O. ODUGUWA ◽  
Y. O. JIMOH ◽  
A. O. FARONBI

A feeding trial was conducted using 104 one week-old anak broilier chicks to evaluate the replacement value of shrimp waste meal (SWM) for fish meal (FM) in broiler diets. Fish meal contribution to the dietary crude protein of the brioiler dietsat was replaced with SWM 0, 33, 66 and 100% of graded levels. Weight gain and feedconverstion ratio were significantly (P > 0.05) reduced with SWM replacing FM at 100% at both the starter and finisher phases. No significant differences (P >0.05) were observed for feed consumption. mortality increased with an increased levle of SWM in the diet at the starter phase. Liver weight increased (P <0.05) with increased level of SWM significantly (P <0.05) increased the abdominal fat. Result of this present study show that the SWM could partially replace 66% of the crude protein of FM in broiler diets without negatively affecting performance or carcass quality 


2012 ◽  
Vol 28 (3) ◽  
pp. 613-622
Author(s):  
Ya. Kozhouharov ◽  
V. Lingorski

The experiment with natural meadow of Agrostis capillaris - Festuca fallax type in Rhodope Mountains (Smolyan region, Southern Bulgaria) shows that according to fertilization variants there is a clear tendency towards earlier start of active vegetation and its next phenophases. Most and almost equal amounts of dry biomass (4.38 and 4.31 t.ha-1) were reported in fertilization with N160P80K80 and N160P80, which exceeded the unfertilized control by 128.12 and 124.48%, respectively. Compared with unfertilized variant, the crude protein content increased in all fertilizing variants, as in complete mineral fertilization with N80-160 accumulates the crudest protein - respectively 314 g.kg-1 and 318 g.kg-1. As regards to other studying chemical indicators of the forage (crude fiber, crude fat, crude ash and nitrogen-free extract substances) the mineral fertilization also had an expressed positive effect.


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