THE EFFECT OF DIETARY MARINE FISH OILS ON THE SERUM CHOLESTEROL LEVELS IN HYPERCHOLESTEROLEMIC CHICKENS

1960 ◽  
Vol 38 (1) ◽  
pp. 19-24 ◽  
Author(s):  
J. D. Wood ◽  
Jacob Biely

An investigation was carried out into the effect of marine fish oils on the serum cholesterol levels in hypercholesterolemic chickens. The oils were fed at the 10% level in the diet. Lingcod liver oil and halibut liver oil prevented the hypercholesterolemic effect of supplementary cholesterol, whereas crude herring oil increased the hypercholesterolemia to the same extent as did corn oil and tallow. Ratfish liver oil, dogfish liver oil, and basking shark liver oil had less noticeable effects on the cholesterol levels. No clear explanation could be given for the observed behavior but there seemed to be a difference in the effects on serum cholesterol of liver oils from teleostei fish and from selachii fish, the former class of liver oils being much more potent in preventing the increase in serum cholesterol concentration in chickens caused by the addition of cholesterol to the diet.

1960 ◽  
Vol 38 (1) ◽  
pp. 19-24 ◽  
Author(s):  
J. D. Wood ◽  
Jacob Biely

An investigation was carried out into the effect of marine fish oils on the serum cholesterol levels in hypercholesterolemic chickens. The oils were fed at the 10% level in the diet. Lingcod liver oil and halibut liver oil prevented the hypercholesterolemic effect of supplementary cholesterol, whereas crude herring oil increased the hypercholesterolemia to the same extent as did corn oil and tallow. Ratfish liver oil, dogfish liver oil, and basking shark liver oil had less noticeable effects on the cholesterol levels. No clear explanation could be given for the observed behavior but there seemed to be a difference in the effects on serum cholesterol of liver oils from teleostei fish and from selachii fish, the former class of liver oils being much more potent in preventing the increase in serum cholesterol concentration in chickens caused by the addition of cholesterol to the diet.


1959 ◽  
Vol 197 (1) ◽  
pp. 102-104 ◽  
Author(s):  
Narindar Nath ◽  
A. E. Harper

ß-Sitosterol added to a diet containing cholesterol alone or with cholic acid, diminished the accumulation of serum and liver cholesterol in the rat. This effect depended upon the quantity of ß-sitosterol added. Addition of ß-sitosterol to a diet containing corn oil enhanced the hypocholesteremic effect of corn oil. Calciferol and Q275 when fed to rats had no significant effect on serum cholesterol concentration, but calciferol caused an increase in the deposition of cholesterol in the liver.


1982 ◽  
Vol 47 (2) ◽  
pp. 213-221 ◽  
Author(s):  
Anthony H. M. Terpstra ◽  
Christopher J. H. Woodward ◽  
Clive E. West ◽  
Henk G. Van Boven

1. Two groups, each of six rabbits, were fed on semi-purified diets containing either 400 g casein or 400 g soya-bean protein/kg for 20 d and then the diets of the two groups were crossed-over.2. Just before the cross-over, the serum cholesterol concentration (mean ± SE) was 3068 ± 592 and 800 ± 143 mg/l for the groups fed on casein and soya-bean protein respectively.3. Changes in the serum cholesterol concentration were observed 1 d after crossing-over the diets. By 10 d, the cholesterol levels in the two groups had also crossed-over.4. The changes in serum cholesterol level after the cross-over were reflected in the very-low-density lipoproteins (VLDL) and low-density lipoproteins (LDL).5. Lipoprotein protein concentrations in the LDL changed in the same way as cholesterol. In the VLDL however, the protein concentration decreased in both groups after the change in diet.6. The cholesterol:protein values for the LDL and VLDL markedly increased in the rabbits changed from the soya-bean-protein diet to the casein diet, reaching a maximum 2 d after the cross-over. In the animals switched from casein to soya-bean protein, the values progressively declined.7. The source of dietary protein exerts a rapid effect on the composition of both the VLDL and LDL which is proposed to be attributed to changes in the number and size of lipoprotein particles.


1961 ◽  
Vol 39 (11) ◽  
pp. 1705-1715 ◽  
Author(s):  
J. D. Wood ◽  
J. Biely ◽  
J. E. Topliff

The cholesterol metabolism of chickens differed in birds of different age and sex. The normal serum cholesterol levels were higher in females than in males and higher in 1-week-old chicks than in mature birds of the same sex. Laying hens were less susceptible to hypercholesterolemia induced by dietary cholesterol than were mature cockerels or young chicks of either sex. Corn oil tended to increase the degree of hypercholesterolemia in all cholesterol-fed birds except young cockerels. A vitamin-A-rich oil, dogfish liver oil, decreased the rise in serum cholesterol level in cholesterol-fed chicks of both sexes, but in mature birds it produced the opposite effect. The addition of 1% cholesterol to the control diet of hens increased the yolk cholesterol concentration of eggs laid by the birds and this increase in concentration was greatly enhanced if 10% corn oil was also present in the diet.


BMJ ◽  
1996 ◽  
Vol 312 (7025) ◽  
pp. 221-221 ◽  
Author(s):  
P. H A Steegmans ◽  
D. Fekkes ◽  
A. W Hoes ◽  
A. A A Bak ◽  
E. van der Does ◽  
...  

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