A NOTE ON THE ENERGY OF ACTIVATION OF THE AMYLASE IN VARIOUS HUMAN BODY FLUIDS

1956 ◽  
Vol 34 (1) ◽  
pp. 6-9 ◽  
Author(s):  
Leslie Kovacs ◽  
Jules Tuba
Keyword(s):  
Activation Energy ◽  
Human Body ◽  
Mean Value ◽  
Body Fluids ◽  
Normal Serum ◽  
The Body ◽  
Energy Of Activation ◽  
Heat Inactivation ◽  
Head Of The Pancreas ◽  
The Mean

The activation energy was determined for the amylase present in the following fluids obtained from the human body: urine, duodenal fluid, saliva, and normal serum, as well as serum from patients with mumps, acute pancreatitis, and carcinoma of the head of the pancreas. Over a temperature range of 4°–37.4 °C., with starch as a substrate, the value of the energy of activation was similar in all cases to that for bacterial α-amylase, and the mean value was 13,740 ± 200 cal./mole. Partial heat inactivation of the enzyme was evident in some cases at 37.4°. On the basis of the evidence obtained it appears that α-amylase is present in all the body fluids examined.

A NOTE ON THE ENERGY OF ACTIVATION OF THE AMYLASE IN VARIOUS HUMAN BODY FLUIDS

1956 ◽  
Vol 34 (1) ◽  
pp. 6-9 ◽  
Author(s):  
Leslie Kovacs ◽  
Jules Tuba
Keyword(s):  
Activation Energy ◽  
Human Body ◽  
Mean Value ◽  
Body Fluids ◽  
Normal Serum ◽  
The Body ◽  
Energy Of Activation ◽  
Heat Inactivation ◽  
Head Of The Pancreas ◽  
The Mean

The activation energy was determined for the amylase present in the following fluids obtained from the human body: urine, duodenal fluid, saliva, and normal serum, as well as serum from patients with mumps, acute pancreatitis, and carcinoma of the head of the pancreas. Over a temperature range of 4°–37.4 °C., with starch as a substrate, the value of the energy of activation was similar in all cases to that for bacterial α-amylase, and the mean value was 13,740 ± 200 cal./mole. Partial heat inactivation of the enzyme was evident in some cases at 37.4°. On the basis of the evidence obtained it appears that α-amylase is present in all the body fluids examined.

Serum immunoglobulins in patients with chronic tonsillitis

1984 ◽  
Vol 98 (12) ◽  
pp. 1213-1216 ◽  
Author(s):  
Harbans Lal ◽  
O. P. Sachdeva ◽  
H. R. Mehta
Keyword(s):  
Immune System ◽  
Mean Value ◽  
The Body ◽  
Antigenic Stimulation ◽  
Chronic Tonsillitis ◽  
Serum Immunoglobulin ◽  
Control Group ◽  
Humoral Immune ◽  
Humoral Immune System ◽  
The Mean

AbstractSerum immunoglobulin (IgG, IgA and IgM) levels were determined in patients with chronic tonsillitis before and one month after tonsillectomy. The preoperative levels of serum IgG, IgA and IgM were significantly higher when compared with the controls. The increase may be due to repeated antigenic stimulation. The post-operative levels for the three immunoglobulins were decreased; however, a significant reduction was observed for IgG only where the mean value was comparable with the control group. The data confirm that tonsillectomy does not disturb the humoral immune system of the body.

scholarly journals The Effect of Propanolol on C-Reactive Protein in Patients with Severe Burns at Dr Soetomo Hospital Surabaya

2021 ◽  
Vol 4 (1) ◽  
pp. 27
Author(s):  
Muhammad Aulia U H ◽  
Iswinarno Doso Saputro ◽  
Magda Rosalina Hutagalung
Keyword(s):  
Treatment Group ◽  
Albumin Level ◽  
Mean Value ◽  
The Body ◽  
Control Group ◽  
Control Group Design ◽  
Severe Burns ◽  
Hypermetabolic State ◽  
Post Test ◽  
The Mean

Background: The incidence of burns in Indonesia progressively increases with the increase in its population and industries. From January to September 2000, 158 patients were treated in the burn unit of Dr Soetomo Hospital with a mortality rate reaching 5,8%. Burns have a direct effect in causing both local and systemic changes in the body, not occurring in other injuries. In severe burns, a hypermetabolic state can occur, which increases cardiac workload and causes muscle atrophy and other morbidities. The purpose of this study is to examine the effect of propranolol on the hypermetabolic state in severely burned patients by measuring various clinical & laboratory parameters.Methods : This is an experimental study using pre and post test control group design with the objective of assessing the treatment outcome with oral propranolol given in 15 consecutive days for burn patients involving 25%- 60% TBSA. Measurements were taken three times, on day 0, 7 and 14.Results : Obtained 16 samples divided into 2 groups. In the treatment group, there was a significant decrease in CRP levels on days 0, 7 and 14 (p <0.05). The Mid Arm Circumference variable did not obtain a significant decreasing on days 0, 7 and 14. The albumin level studied showed a significant decreasing on day 0 & 7 days with a value of p = 0.045. From the comparison between the two groups, there were significant differences in CRP levels on days 0 & 14, with the mean value of the treatment group -5.12 + 2.88 and the mean value of the control group 2.86 + 7.37, and the value of p = 0.019.Conclusions: This study successfully proved that the administration of propranolol can overcome the effects of hypermetabolism which is characterized by decreasing in CRP levels.

Follow up: palmitic acid ester of tetrahydrocannabinol (THC) and palmitic acid diester of 11-hydroxy-THC – unsuccessful search for additional THC metabolites

2021 ◽  
Vol 36 (3) ◽  
pp. 199-203
Author(s):  
Michael Kraemer ◽  
Cornelius Hess ◽  
Alexandra Maas ◽  
Burkhard Madea ◽  
Andras Bilkei-Gorzo ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Palmitic Acid ◽  
Human Body ◽  
Acid Ester ◽  
Body Fluids ◽  
The Body ◽  
Primary Metabolite ◽  
Tissue Samples ◽  
A Site ◽  
Liquid Chromatographic

Abstract Objectives In a previous investigation we searched for the occurrence of palmitic acid ester compounds of delta9-tetrahydrocannabinol (THC) and its primary metabolite 11-hydroxy-delta9-THC (11-OH-THC) in human body fluids and tissues (THC palmitic acid monoester [THC-Pal] and 11-OH-THC palmitic acid diester [11-OH-THC-DiPal]). As those esters could not be detected in various human body fluids (e.g. blood) or tissues (e.g. adipose tissue) we extended the investigation analyzing adipose tissue samples of mice previously given synthetic THC or a cannabis extract. Methods In total, 48 adipose tissue samples previously tested positive for THC by means of a liquid chromatographic triple quadrupole mass spectrometric (LC-QQQ-MS) method were analyzed for the presence of THC-Pal and 11-OH-THC-DiPal by means of LC-QQQ-MS. Results THC-Pal and 11-OH-THC-DiPal were not detected among the adipose tissue samples analyzed despite the presence of high THC concentrations within the adipose tissue. THC concentrations in adipose tissue were in a range of approximately 7–2,595 ng/g (median: 468 ng/g, average: 704 ng/g). Conclusions A (site-specific) synthesis of 11-OH-THC palmitic acid monoesters (11-hydroxy-delta9-THC-1-palmitate and 11-palmitoyloxy-delta9-THC) still remains to be done. After synthesis of these monoesters, their presence in the body fluids and tissues after THC administration should be investigated.

A model for the effect of bias for cholesterol on the population at risk.

1988 ◽  
Vol 34 (11) ◽  
pp. 2256-2259 ◽  
Author(s):  
M H Kroll ◽  
M Ruddel ◽  
R J Elin
Keyword(s):  
At Risk ◽  
Standard Deviation ◽  
Reference Values ◽  
Gaussian Distribution ◽  
Population Distribution ◽  
Reference Value ◽  
Mean Value ◽  
The Body ◽  
Methodological Bias ◽  
The Mean

Abstract The location of the Reference Value for an analyte within the population distribution affects the magnitude of error due to methodological bias. Using the gaussian distribution, we evaluated the effects of systematic and proportional biases of the method (positive and negative), mean value, and standard deviation on the magnitude of error. We chose four Reference Values for cholesterol as a model. For a population with a mean of 2.0 and SD of 0.36 g of cholesterol per liter, a 3% positive proportional bias causes sixfold more error at the 50th percentile than at the 97.5th. In general, the error for a given bias (proportional or systematic) is greater for a Reference Value within the body than at the tails of the distribution. Further, the magnitude of the error varies as a function of the mean and standard deviation of the population.

Effect of 1,25-(OH)2D3 on jejunal absorption of magnesium in patients with chronic renal disease

1980 ◽  
Vol 238 (4) ◽  
pp. G349-G352 ◽  
Author(s):  
A. C. Schmulen ◽  
M. Lerman ◽  
C. Y. Pak ◽  
J. Zerwekh ◽  
S. Morawski ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Normal Subjects ◽  
Mean Value ◽  
Normal Serum ◽  
Perfusion Technique ◽  
Dihydroxyvitamin D3 ◽  
Jejunal Absorption ◽  
The Mean

These studies were performed to see if jejunal malabsorption of magnesium in patients with chronic renal disease was influenced by therapy with 1 alpha, 25-dihydroxyvitamin D3 [1,25-(OH)2D3; 2 microgram/day by mouth for 7 days]. This treatment restored normal serum concentrations of the vitamin D metabolite from 0.9 +/- 0.2 to 4.2 +/- 0.6 ng/dl. Jejunal absorption of magnesium, measured by a triple-lumen constant-perfusion technique, was enhanced in each of the seven patients by this therapy. The mean value rose from 0.04 +/- 0.02 to 0.13 +/- 0.02 mmol . 30 cm-1 . h-1. This last value is similar to the magnesium absorption rate in untreated normal subjects. These results demonstrate that magnesium absorption in the human jejunum is dependent on vitamin D, and they show that 1 alpha,25-dihydroxyvitamin D3 therapy in patients with chronic renal failure is associated with an enhanced jejunal absorption of magnesium.

scholarly journals TRUNK BALANCE EXERCISE LEBIH BAIK DARI PADA STRENGTHENING BACK EXERCISE DALAM MENINGKATKAN KESEIMBANGAN KINERJA OTOT ERECTOR SPINE PADA PEMAIN FUTSAL PEMULA

2017 ◽  
Author(s):  
Yusuf Nasirudin ◽  
Dewa Putu Gde Purwa Samatra ◽  
Wahyuddin ◽  
Susy Purnawati ◽  
Ni Made Linawati ◽  
...  
Keyword(s):  
Hypothesis Test ◽  
Mean Value ◽  
The Body ◽  
Average Value ◽  
Balance Exercise ◽  
Strengthening Exercise ◽  
Significant Difference ◽  
Trunk Balance ◽  
The Mean ◽  
Better Than

In the game of futsal, work of postural muscle balance needed to maintain the stability of the body for receiving the pass and put the ball into the other team's goal at the time of attack, changing the direction of movement quickly when returning to their respective positions and avoid of back disorder. This research is a form of experimental research that will test the effectiveness of the provision of trunk balance exercise is better than the strengthening of back exercises to improve muscle work balance of erector spine on futsal beginner players, in this study sample will be divided into two groups, the first group will be given trunk balance exercise to improve balance of erectorspine muscles work in futsal begginer players, the second group will be given back strengthening exercise to improve balance of erectorspine muscles work in futsal begginer players.This study was conducted for 6 weeks and the intervention performed 18 times during the study period. Samples measured by surface electromyography to measure work of right and left erector muscle by calculating the proportion of the work on the muscle, the measurement is performed at before the intervention and then intervention in accordance with the grouping which has been divided and then after completion of the intervention, the samples will be re-measured to obtain the value of the intervention.The results of the first group who has been given of trunk balance exercise shows the average value of the before treatment (83.82 ± 2.94) % and the mean value of the after treatment (96.74 ± 2.39) %, and in the second group who has been given strengthening back exercise shows the mean value of the before treatment (88.29 ± 1.89) % and the mean value after treatment (95.91 ± 1.75) %, with the probability value of both groups is 0.000 (p <0.05), and can be expressed there is a significant difference between both groups. In the fourth hypothesis test conducted comparative results of both groups, using independent samples t-test using mean value of the first and second groups, in the first group (12.92 ± 2.94) %, and the second group (7.61 ± 2.12) %, with a probability value 0.000 (p<0.05) and can be expressed in statistical analysis is no significant difference between both treatments were carried out and that means, giving trunk balance exercise is better than back strengthening exercise to improve balance of erector spine muscles work on futsal beginner players.

Some sources of error and possible bias in Danscan ultrasonic measurements of cattle

1983 ◽  
Vol 37 (1) ◽  
pp. 67-71
Author(s):  
J. P. Gibson ◽  
J. C. Alliston
Keyword(s):  
Measurement Error ◽  
Mean Value ◽  
Time Of Day ◽  
Error Distribution ◽  
The Body ◽  
Residual Error ◽  
Ultrasonic Measurements ◽  
The Mean ◽  
Ultrasonic Images ◽  
Account Variation

ABSTRACTPhotographs of ultrasonic images of 10 animals were taken. Two replicate photographs were taken at each of four body positions (10th rib, 13th rib, 3rd lumbar and hindquarter) on both sides of the body in the morning and the afternoon of the day of scanning. Several measurements were taken on each photograph by an experienced interpreter. Replicate photographs failed to account for all possible sources of measurement error. Since neither time of day nor side of the body affected the mean value, taking observations at different times of the day or on both sides of the body could permit most sources of measurement error to be taken into account. Variation due to errors of measurement and differences among animals are presented. The residual error distribution contained several extreme outliers.It was concluded that a better understanding of all the sources of bias and error will be needed if ultrasonic measurements are to be more widely used.

Selenium concentrations in tissues of sheep given a subcutaneous injection of barium selenate or sodium selenate

1994 ◽  
Vol 34 (5) ◽  
pp. 581 ◽  
Author(s):  
JA Archer ◽  
GJ Judson
Keyword(s):  
Body Weight ◽  
Subcutaneous Injection ◽  
Mean Value ◽  
The Body ◽  
Transient Increase ◽  
Sodium Selenate ◽  
Human Consumption ◽  
Protective Mechanism ◽  
Treatment Groups ◽  
The Mean

Young sheep were allocated to 6 treatment groups, each of 8 ewes and 8 wethers. Treatments given were nil, 0.1, or 0.5 mg selenium (Se)/kg body weight as a subcutaneous injection of sodium selenate (Na2SeO4), and 0.8, 1.4, or 2.9 mg Se/kg body weight as a subcutaneous injection of barium selenate (BaSeO4). At 14, 28, 56, and 112 days after treatment, 2 ewes and 2 wethers from each group were slaughtered and samples of blood, liver, kidney, cardiac and skeletal muscle, lymph nodes, and faeces were collected for Se assay. On days 0, 1, 3, 7, 13, 27, and 55 blood and spot faecal samples were taken for Se assay from the 24 sheep selected for slaughter on day 112. In sheep given Na2Se04 there was a rapid but transient increase in the mean Se concentration in tissues, particularly the liver of sheep given the highest dose of Na2SeO4. In these sheep on days 14,28,56, and 112 the respective mean liver concentrations were 169, 62,25, and 6.9 �mol/kg DM: the mean value on day 14 was 15 times the mean value in untreated sheep. In sheep given BaSeO4 there was a gradual increase in mean Se concentration of tissues during the experiment. Faecal Se concentrations increased in sheep given the Se injections. The marked but transient increase in liver Se concentrations in sheep given Na2SeO4 suggests that this organ provides an important protective mechanism against toxicity by readily accumulating and excreting Se into the gut. Our results indicate that the BaSeO4 doses were unlikely to cause Se toxicity in young sheep or result in Se residues in tissues above those recommended for human consumption. The BaSeO4 should be administered subcutaneously in the neck or other sites of the body not sold for human consumption, since deposits of BaSeO4 remain at the site of injection for at least 112 days and may be dangerous if inadvertently consumed.

SUBCLINICAL HYPOTHYROIDISM IN ADDISON'S DISEASE

1979 ◽  
Vol 91 (4) ◽  
pp. 674-679 ◽  
Author(s):  
Jens Faber ◽  
Dorte Cohn ◽  
Carsten Kirkegaard ◽  
Morten Christy ◽  
Kaj Siersbæk-Nielsen ◽  
...  
Keyword(s):  
Addison’S Disease ◽  
Mean Value ◽  
Normal Serum ◽  
Control Group ◽  
Addison's Disease ◽  
Normal Range ◽  
Microsomal Antibody ◽  
The Mean ◽  
Thyroid Microsomal Antibodies ◽  
Serum Tsh

ABSTRACT Fourteen patients with Idiopatic Addison's disease (IAD) were studied in order to detect a possible subclinical hypothyroid state. All were clinically euthyroid with normal serum thyroxine (T4) and serum 3,5′,3′-triiodothyronine (T3). Eleven had circulating thyroid microsomal antibodies in blood. The mean basal serum TSH was significantly higher than that of the control group but only three patients had values above the upper normal range. The mean value of serum T4 was decreased as compared to that of the normal persons, while serum 3,3′,5′-triiodothyronine was elevated. 7.5 mU bovine thyrotrophin per kilogram body weight injected intravenously caused a rise in serum T3 not different from the response in normals. However, as well increasing serum TSH as increasing microsomal antibody titer correlated significantly to decreasing thyroidal release of T3. Our results suggest that clinically euthyroid patients suffering from IAD might have a beginning thyroidal insufficiency because of a progressive immunological damage of the thyroid.

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