ZINC, CARBONIC ANHYDRASE, AND PHOSPHATASE IN THE PROSTATIC GLANDS OF THE RAT

1955 ◽  
Vol 33 (2) ◽  
pp. 181-190 ◽  
Author(s):  
M. I. Fischer ◽  
A. O. Tikkala ◽  
C. A. Mawson
Keyword(s):  
Carbonic Anhydrase ◽  
Small Proportion ◽  
Soft Tissues ◽  
Zinc Content ◽  
Carbonic Anhydrase Activity ◽  
Ventral Prostate ◽  
Alkaline Phosphatases ◽  
Acid And Alkaline Phosphatases ◽  
Consistent Relationship

The concentration of zinc in the dorsolateral prostate of the rat increases rapidly during infancy, reaching a maximum of 250-300 μgm./gm. at an age of about 160 days. This figure is 10 times as high as that found for most other soft tissues. Carbonic anhydrase activity behaves similarly, with a maximum at about 200 days, when it is 100 times the amount found in most other organs. Zinc which occurs as part of the carbonic anhydrase molecule forms only a small proportion of the total zinc content of the tissue at all ages. Zinc and carbonic anhydrase occur only in small amounts in the ventral prostate. The activities of acid and alkaline phosphatases in ventral and dorsolateral prostates are not correlated with age, and zinc and enzyme concentrations bear no consistent relationship to one another. Differences between the phosphatases of liver and prostatic complex in the rat are briefly discussed.

ZINC, CARBONIC ANHYDRASE, AND PHOSPHATASE IN THE PROSTATIC GLANDS OF THE RAT

1955 ◽  
Vol 33 (1) ◽  
pp. 181-190 ◽  
Author(s):  
M. I. Fischer ◽  
A. O. Tikkala ◽  
C. A. Mawson
Keyword(s):  
Carbonic Anhydrase ◽  
Small Proportion ◽  
Soft Tissues ◽  
Zinc Content ◽  
Carbonic Anhydrase Activity ◽  
Ventral Prostate ◽  
Alkaline Phosphatases ◽  
Acid And Alkaline Phosphatases ◽  
Consistent Relationship

The concentration of zinc in the dorsolateral prostate of the rat increases rapidly during infancy, reaching a maximum of 250-300 μgm./gm. at an age of about 160 days. This figure is 10 times as high as that found for most other soft tissues. Carbonic anhydrase activity behaves similarly, with a maximum at about 200 days, when it is 100 times the amount found in most other organs. Zinc which occurs as part of the carbonic anhydrase molecule forms only a small proportion of the total zinc content of the tissue at all ages. Zinc and carbonic anhydrase occur only in small amounts in the ventral prostate. The activities of acid and alkaline phosphatases in ventral and dorsolateral prostates are not correlated with age, and zinc and enzyme concentrations bear no consistent relationship to one another. Differences between the phosphatases of liver and prostatic complex in the rat are briefly discussed.

scholarly journals Carbonic Anhydrase Activity in Plants in Relation to Zinc Content

1952 ◽  
Vol 5 (2) ◽  
pp. 244 ◽  
Author(s):  
JG Wood ◽  
Pamela M Sibly
Keyword(s):  
Life Cycle ◽  
Carbonic Anhydrase ◽  
Zinc Content ◽  
Carbonic Anhydrase Activity ◽  
Deficiency Symptoms ◽  
Maximum Value ◽  
Chloroplast Fraction

Throughout the life cycle of oat plants carbonic anhydrase activity, which is restricted to the non-chloroplast fraction of leaves, reaches a maximum value and then decreases. After appearance of deficiency symptoms carbonic anhydrase activity is less in zinc-deficient plants than in fully manured controls of the same age and is associated with a lower zinc content of the leaves.

scholarly journals THE RELATIONSHIP BETWEEN CARBONIC ANHYDRASE ACTIVITY AND ZINC CONTENT OF ERYTHROCYTES IN NORMAL, IN ANEMIC AND OTHER PATHOLOGIC CONDITIONS

Blood ◽  
1949 ◽  
Vol 4 (5) ◽  
pp. 467-478 ◽  
Author(s):  
BERT L. VALLEE ◽  
HERBERT D. LEWIS ◽  
MARK D. ALTSCHULE ◽  
JOHN G. GIBSON
Keyword(s):  
Carbonic Anhydrase ◽  
Red Blood Cells ◽  
Pernicious Anemia ◽  
Blood Cells ◽  
Zinc Concentration ◽  
Zinc Content ◽  
Carbonic Anhydrase Activity ◽  
Almost All ◽  
The Relationship ◽  
Parallel Fashion

Abstract A good correlation exists between zinc content and carbonic anhydrase activity of the red blood cells under all conditions studied, including anemia and polycythemia. In almost all patients with anemias other than pernicious anemia, both zinc and carbonic anhydrase levels were lowered in parallel fashion. These changes were proportional to decreases in hematocrit and hemoglobin levels and erythrocyte counts so that both zinc and carbonic anhydrase values per unit of RBC were in the normal range. In a few instances of anemia associated with leukemia and in one of sickle cell anemia, neither zinc content nor carbonic anhydrase activity was decreased in proportion to the anemia; in these cases the zinc and carbonic anhydrase levels per unit of blood were both elevated to the same degree. Patients with pernicious anemia showed no decrease in absolute values for zinc and carbonic anhydrase activity in spite of marked lowering of hematocrit and hemoglobin levels and of erythrocyte count. Accordingly, both zinc concentration and carbonic anhydrase activity per unit of blood were elevated, often to a marked degree. These increases were parallel, varying inversely with the degree of anemia; when they regressed under treatment, both did so at the same rate. There are no methods available for estimating carbonic anhydrase concentration; all methods now in use measure only the activity of the enzyme. It is suggested that zinc concentration could be used as an indicator of carbonic anhydrase content of the red blood cells.

1123: Renal Oxalate Transport Depends on Local Carbonic Anhydrase Activity in the Proximal Tubule

2004 ◽  
Vol 171 (4S) ◽  
pp. 296-296
Author(s):  
Michael Straub ◽  
Joséphine Befolo-Elo ◽  
Richard E Hautmann ◽  
Edgar Braendle
Keyword(s):  
Carbonic Anhydrase ◽  
Proximal Tubule ◽  
Carbonic Anhydrase Activity ◽  
Oxalate Transport

Progestation

1967 ◽  
Vol 56 (3_Suppla) ◽  
pp. S7-S45 ◽  
Keyword(s):  
Tritiated Thymidine ◽  
Succinic Dehydrogenase ◽  
Glandular Epithelium ◽  
Synthetic Activity ◽  
Cell Renewal ◽  
Pulse Labelling ◽  
Uterine Receptivity ◽  
Alkaline Phosphatases ◽  
Monocytic Cells ◽  
Acid And Alkaline Phosphatases

ABSTRACT Autoradiographic, enzymic and histologic studies on uteri of pregnant rats were carried out to follow the endometrial modifications which take place during progestation (days L0 – L4) and culminate in the state of uterine receptivity essential for ovum-implantation. Pulse labelling with tritiated thymidine (radioactive DNA precursor) on L0, L1 and L2 revealed a sequence of cell renewal in luminal and glandular epithelium and endometrial stroma. On L3 and L4 stromal cells showed extensive incorporation of tritiated thymidine. This synthetic activity was associated with endometrial preparation for decidualization and was evoked at least in part, by the surge of oestrogen on L3. All layers of the uterine wall were heavily infiltrated on L0 and resembled the site of an acute inflammatory reaction. Subsequently, polymorphonuclear infiltration diminished and monocytic cells predominated. On L3 a spatial arrangement was observed: eosinophiles were concentrated in the basal endometrium and monocytic cells in the subepithelial stroma. A comparison was made between such a shift in migratory cells in the uterus and similar phenomena which occur in inflammatory and immune reactions. Activities of acid and alkaline phosphatases, of ATP-ase and succinic dehydrogenase were low on L0 and L1 during the periods of infiltration, degeneration and regeneration of luminal and glandular epithelium. Enzymic activities increased on the following days, (L3 and L4). Vascular dilation and engorgement and endometrial oedema were observed near the blastocysts on L4. Most blastocysts incorporated tritiated thymidine after 14.00 h on L4, but some showed uptake before loss of the zona which occurs usually between 14.00 and 16.00 h; therefore, it was assumed that the permeability of the zona increases prior to being shed. Activities of succinic dehydrogenase and acid and alkaline phosphatases were demonstrable in blastocysts on L4 while they were still »free« in the uterine lumen.

Effects of Kanwa on Rat Gastrointestinal Phosphatases

2010 ◽  
Vol 3 (3) ◽  
pp. 1147-1152
Author(s):  
Jacob Bamaiyi ◽  
Omajali ◽  
Sanni Momoh
Keyword(s):  
Alkaline Phosphatase ◽  
Small Intestine ◽  
Acid Phosphatase ◽  
Sodium Carbonate ◽  
Elevated Level ◽  
Food Additive ◽  
Alkaline Phosphatases ◽  
Acid And Alkaline Phosphatases ◽  
Diagnostic Indices ◽  
High Level

This study investigates the effects of kanwa on rat gastrointestinal phosphatases. The rats were administered 7% w/v concentration of  trona (Kanwa) orally for a period of two weeks in order to investigate how this compound is being used as food additive in some homes in Nigeria. The Kanwa used in this study was the handpicked variety obtained from sellers from Anyigba market in eastern part of Kogi State, Nigeria. Kanwa, a hydrated sodium carbonate (Na2CO3NaHCO3.2H2O) was obtained as a dried lake salt. Acid phosphatase has the ability to dephosphorylate molecules containing phosphate group. The decreased and elevated level in serum or plasma acid and alkaline phosphatases serves as diagnostic indices for various diseases. Results showed that there was increase and decrease of acid phosphatase (ACP) activities in both the stomach and small intestine. The activities of alkaline phosphatase (ALP) fluctuated in the small intestine. However, in the stomach, an increase activity of ALP was noticed throughout the period of ‘Kanwa’ administration. We concluded that although the level of ‘Kanwa’ consumed in most homes may not be toxic if not taken continuously or repeatedly. Thus, continuous consumption should be discouraged as accumulation of high level of ‘Kanwa’ may cause damages or injuries to the various organs/tissues and may disrupt normal body function.

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