Lysis of zoopathogenic fungi by streptomycetes

1971 ◽  
Vol 17 (4) ◽  
pp. 521-523 ◽  
Author(s):  
Dexter H. Howard ◽  
Rishab K. Gupta
Keyword(s):  
Yeast Cell ◽  
Cell Walls ◽  
Histoplasma Capsulatum ◽  
Sporothrix Schenckii ◽  
Blastomyces Dermatitidis ◽  
Streptomyces Spp

The cell walls of the yeast cell phases of Histoplasma capsulatum, Blastomyces dermatitidis, and Sporothrix schenckii were lysed by enzymes formed during the growth of Streptomyces spp. Mycelial elements of H. capsulatum were not lysed by the streptomycetes.

scholarly journals Interaction of Blastomyces dermatitidis, Sporothrix schenckii, and Histoplasma capsulatum with Acanthamoeba castellanii

2004 ◽  
Vol 72 (6) ◽  
pp. 3478-3488 ◽  
Author(s):  
Judith N. Steenbergen ◽  
Joshua D. Nosanchuk ◽  
Stephanie D. Malliaris ◽  
Arturo Casadevall
Keyword(s):  
Histoplasma Capsulatum ◽  
Sporothrix Schenckii ◽  
Acanthamoeba Castellanii ◽  
Fungal Growth ◽  
Laboratory Strain ◽  
Yeast Cells ◽  
Blastomyces Dermatitidis ◽  
Mammalian Host ◽  
Human Pathogens ◽  
Dimorphic Fungi

ABSTRACT Several dimorphic fungi are important human pathogens, but the origin and maintenance of virulence in these organisms is enigmatic, since an interaction with a mammalian host is not a requisite for fungal survival. Recently, Cryptococcus neoformans was shown to interact with macrophages, slime molds, and amoebae in a similar manner, suggesting that fungal pathogenic strategies may arise from environmental interactions with phagocytic microorganisms. In this study, we examined the interactions of three dimorphic fungi with the soil amoeba Acanthameobae castellanii. Yeast forms of Blastomyces dermatitidis, Sporothrix schenckii, and Histoplasma capsulatum were each ingested by amoebae and macrophages, and phagocytosis of yeast cells resulted in amoeba death and fungal growth. H. capsulatum conidia were also cytotoxic to amoebae. For each fungal species, exposure of yeast cells to amoebae resulted in an increase in hyphal cells. Exposure of an avirulent laboratory strain of H. capsulatum to A. castellanii selected for, or induced, a phenotype of H. capsulatum that caused a persistent murine lung infection. These results are consistent with the view that soil amoebae may contribute to the selection and maintenance of certain traits in pathogenic dimorphic fungi that confer on these microbes the capacity for virulence in mammals.

In vitro interactions between Blastomyces dermatitidis and other zoopathogenic fungi

1988 ◽  
Vol 34 (7) ◽  
pp. 897-900 ◽  
Author(s):  
Vishnu P. Chaturvedi ◽  
Harbans S. Randhawa ◽  
Sudha Chaturvedi ◽  
Zia U. Khan
Keyword(s):  
Candida Albicans ◽  
Histoplasma Capsulatum ◽  
Sporothrix Schenckii ◽  
Blastomyces Dermatitidis ◽  
Microsporum Gypseum ◽  
Biotic Factors ◽  
Pseudallescheria Boydii ◽  
Natural Systems ◽  
In Vitro Interactions

The results of in vitro interactions between colonies of Blastomyces dermatitidis and six other zoopathogenic fungi are reported. The interactions were found to range from neutral with Histoplasma capsulatum and Candida albicans to strongly antagonistic with Microsporum gypseum, Pseudallescheria boydii, and Sporothrix schenckii, and including lysis by Cryptococcus neoformans. These observations suggest that interactions between zoopathogenic fungi may be one of the biotic factors likely to influence the occurrence of B. dermatitidis in natural systems.

ON THE CELL WALLS OF DIMORPHIC FUNGI CAUSING SYSTEMIC INFECTIONS

1954 ◽  
Vol 1 (1) ◽  
pp. 1-5 ◽  
Author(s):  
F. Blank
Keyword(s):  
Cell Walls ◽  
Histoplasma Capsulatum ◽  
Paracoccidioides Brasiliensis ◽  
Blastomyces Dermatitidis ◽  
Growth Phases ◽  
Electron Microscopic ◽  
Dimorphic Fungi ◽  
Polymeric Substance ◽  
Systemic Infections ◽  
Microscopic Investigations

Cultures of the mycelial and tissue-like growth phases of Blastomyces dermatitidis, Paracoccidioides brasiliensis, Histoplasma capsulatum, and Sporotrichum Schenckii were extracted and oxidized as described by Scholl in 1908. Debye–Scherrer diagrams of the so prepared cell walls show the presence of chitin in both growth phases of each fungus investigated, and give no evidence of the presence of cellulose or another high polymeric substance in the membranes. Nitrogen determinations of the same material corroborate these findings. Electron-microscopic investigations of the isolated chitin of Blastomyces dermatitidis did not reveal any substantial difference in the submicroscopic structures of the framework of the mycelial and yeast-like growth phases.

Recognition of Fungal Components by the Host Immune System

2020 ◽  
Vol 21 (3) ◽  
pp. 245-264 ◽  
Author(s):  
Laura C. García-Carnero ◽  
José A. Martínez-Álvarez ◽  
Luis M. Salazar-García ◽  
Nancy E. Lozoya-Pérez ◽  
Sandra E. González-Hernández ◽  
...  
Keyword(s):  
Immune System ◽  
Histoplasma Capsulatum ◽  
Paracoccidioides Brasiliensis ◽  
Sporothrix Schenckii ◽  
Clinical Importance ◽  
Pathogenic Fungi ◽  
Diagnostic Tools ◽  
Future Research ◽  
Host Immune System ◽  
Fungal Antigens

: By being the first point of contact of the fungus with the host, the cell wall plays an important role in the pathogenesis, having many molecules that participate as antigens that are recognized by immune cells, and also that help the fungus to establish infection. The main molecules reported to trigger an immune response are chitin, glucans, oligosaccharides, proteins, melanin, phospholipids, and others, being present in the principal pathogenic fungi with clinical importance worldwide, such as Histoplasma capsulatum, Paracoccidioides brasiliensis, Aspergillus fumigatus, Candida albicans, Cryptococcus neoformans, Blastomyces dermatitidis, and Sporothrix schenckii. Knowledge and understanding of how the immune system recognizes and responds to fungal antigens are relevant for the future research and development of new diagnostic tools and treatments for the control of mycosis caused by these fungi.

scholarly journals Peptidogalactomannan from Histoplasma capsulatum yeast cell wall: role of the chemical structure in recognition and activation by peritoneal macrophages

2021 ◽  
Author(s):  
Giulia Maria Pires dos Santos ◽  
Gustavo Ramalho Cardoso dos Santos ◽  
Mariana Ingrid Dutra da Silva Xisto ◽  
Rodrigo Rollin-Pinheiro ◽  
Andréa Regina de Souza Baptista ◽  
...  
Keyword(s):  
Cell Wall ◽  
Yeast Cell ◽  
Chemical Structure ◽  
Histoplasma Capsulatum ◽  
Peritoneal Macrophages ◽  
Yeast Cell Wall

scholarly journals Yeast cell walls adsorption capacity

2020 ◽  
Vol 613 ◽  
pp. 012143
Author(s):  
V V Solovyov ◽  
A M Marhunova ◽  
O L Permiakova ◽  
T V Voblikova ◽  
Yu O Semenova
Keyword(s):  
Yeast Cell ◽  
Adsorption Capacity ◽  
Cell Walls

Sporothrix schenckii Isolated from Edible Black Fungus Mushrooms

1983 ◽  
Vol 46 (8) ◽  
pp. 714-716 ◽  
Author(s):  
NURIA KAZANAS ◽  
GEORGE J. JACKSON
Keyword(s):  
Yeast Cell ◽  
Sporothrix Schenckii ◽  
Edible Mushrooms ◽  
Cell Form ◽  
Far Eastern

Sporothrix schenckii, a fungus which is pathogenic to humans, was recovered from imported desiccated black fungus mushrooms [Auricularia polytrichia (Mont.) Sacc.] usually used in preparing Far Eastern cuisine. Identification was based on microscopic and gross morphology, dimorphism at 25 and 37°C and reactivity with fluorescein-labeled antibodies specific for the yeast-cell form of the fungus. This is the first known report of S. schenckii in or on edible mushrooms.

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