Haematological changes in elite kayakers during a training season

2012 ◽  
Vol 37 (6) ◽  
pp. 1140-1146 ◽  
Author(s):  
Grasiely Faccin Borges ◽  
Luis Manuel Pinto Lopes Rama ◽  
Susana Pedreiro ◽  
Fátima Rosado ◽  
Francisco Alves ◽  
...  
Keyword(s):  
Body Mass ◽  
Hemoglobin Concentration ◽  
Training Load ◽  
Control Group ◽  
Distribution Width ◽  
Training Cycle ◽  
Haematological Changes ◽  
Baseline Values ◽  
Intense Training ◽  
Post Hoc

This study monitored haematological markers in response to training load in elite kayakers during a training season. The sample comprised eight elite kayakers aged 22 ± 4.2 years with a 77.2 ± 6.7 kg body mass and a 177.5 ± 5.6 cm stature. The initial [Formula: see text]O2max was 61.2 ± 5.5 mL·kg–1·min–1. The control group consisted of six healthy males, aged 18.6 ± 1.1 years, with an 81.3 ± 13.8 kg body mass and a 171.9 ± 4.5 cm stature. Blood samples were collected at the beginning of the training season after an off-training period of six weeks (t0), at the 11th week after the application of high training volumes (t1), at the 26th week after an intense training cycle (t2), and at the 31st week at the end of a tapering phase (t3). Differences between time points were detected using ANOVA and the Bonferroni post hoc test. Significant changes were found after the intense training cycle (t2), lymphocytes decreased while haemoglobin, mean corpuscular volume, mean corposcular haemoglobin, mean concentration of corpuscular hemoglobin concentration, platelets distribution width, and red blood cell distribution width values increased when compared with baseline values. At t3, a reduction in monocyte numbers and an increase in mean platelet volume compared with baseline values were seen. By reducing the volume and intensity of training, many variables returned to values close to those at baseline. Although many athletes had accumulated responses over time due to training, they still suffered transient changes that appear to be influenced by training load. Haemorheology monitoring may help detect health risks, especially during times of intensified training.

scholarly journals Markers of Anemia in Children with Type 1 Diabetes

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Ewa Rusak ◽  
Anna Rotarska-Mizera ◽  
Piotr Adamczyk ◽  
Bogdan Mazur ◽  
Joanna Polanska ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Vitamin B12 ◽  
Hemoglobin Concentration ◽  
Control Group ◽  
Mean Corpuscular Hemoglobin ◽  
Red Cell ◽  
Cell Distribution ◽  
Corpuscular Hemoglobin ◽  
Distribution Width

Aim. The aim of the study was to assess markers of anemia in type 1 diabetes (T1D) children, compare them to results obtained in the control group, and estimate their relation to BMI SDS. Methods. 94 (59% ♀) T1D children without other autoimmune disorders, aged 12.5 ± 4.1 years, T1D duration: 4.2 ± 3.6 years, HbA1c 7.3 ± 1.5% (57 ± 12.6 mmol/mol). Sex- and age-matched controls (43 children). In all children, anthropometric measurements, the blood count, iron turnover parameters, and vitamin B12 concentration were taken. Results. T1DM children had significantly higher red cell distribution width (RDW) (13.6 versus 12.6%; p<0.001), hepcidin (0.25 versus 0.12 ng/ml; p<0.001), and vitamin B12 concentrations (459 versus 397 pg/ml; p<0.01) and lower TIBC (59.09 versus 68.15 μmol/l; p<0.001) than in the control group. Logistic regression revealed that RDW, TIBC (both p<0.001), and hepcidin (p<0.05) significantly differentiated both groups. In T1DM children, BMI SDS negatively correlated with vitamin B12 (p<0.01) concentration and mean corpuscular hemoglobin concentration (p<0.05) and positively with TIBC (p<0.01) and HbA1c (p<0.001). Conclusions. Patients and controls differed especially in terms of RDW and TIBC. In studied T1DM children, BMI SDS was associated to iron metabolism parameters and vitamin B12 concentration.

scholarly journals Hepatoprotective and immune-reconstitution potentials of carrot-ginger blend among HIV-infected patients taking antiretroviral therapy in Kaduna, Nigeria

Bio-Research ◽  
2021 ◽  
Vol 19 (2) ◽  
pp. 1328-1341
Author(s):  
Zamani Pius Joshua ◽  
Muawiyam Musa Abarshi ◽  
Ibrahim Sani ◽  
Owolabi Adeyemi Olumuyiwa ◽  
Sanusi Bello Mada ◽  
...  
Keyword(s):  
Body Mass Index ◽  
T Cell ◽  
Antiretroviral Therapy ◽  
T Lymphocytes ◽  
Body Mass ◽  
Cd4 T Cell ◽  
Control Group ◽  
Aspartate Transaminase ◽  
Cell Counts ◽  
Baseline Values

Hepatotoxicity, micronutrients insufficiency and cost of micronutrient supplements are challenges faced by HIV infected patients on antiretroviral therapy (ART). This study investigated the effect of natural plant micronutrients (vitamins A, C, and E, selenium and Zinc supplements from carrot-ginger (75:25) blend on liver enzymes: Alanine transaminase (ALT) and Aspartate transaminase (AST), CD4 +  T lymphocytes and body mass index (BMI) of HIV-infected-patients taking ART. Ninety HIV-infected-patients attending Special Treatment Clinic, Kafanchan General Hospital, Kaduna State, Nigeria, were randomized into three groups of thirty patients each: Group 1 is control group and received ART alone, Group 2 is standard group and received ART with ready to use commercial micronutrient supplement (SelACER supplement) while Group 3 is supplement group and received ART + Carrot-Ginger blend for 90 days. Serum Alanine, Aspartate transaminase, CD4 + T lymphocytes and BMI were assessed using standard methods at baseline (day 0), 30 days, 60 days and 90 days. The results indicated that patients on CarrotGinger blend and SelACER micronutrients supplements show significant (p<0.05) reduction in ALT and AST level. However, there was no significant (p>0.05) difference in patients treated with ART alone when compared to their baseline values. The results indicated that patients on carrot-ginger blend and SelACE® supplements had significant (p<0.05) increase in BMI, CD4+ T-cell counts, serum vitamins A, C, E, selenium and zinc from day zero. There was no significant (p>0.05) difference in patients treated with ART alone compared to their baseline values. In addition, patients on SelACE® supplement revealed significant (p<0.05) difference in their mean BMI, CD4+ T-cell counts, serum vitamins A, C, E, Selenium and Zinc compared to patients on carrot-ginger blend after 90 days. The results also indicated a strong positive association (r=0.97) between serum ALT and AST activity and between CD4+ T cell counts and body mass index (r=0.77) after 90 days. Therefore, micronutrients supplementation of HIV patients during ART treatment with Carrot-Ginger blend could also be a beneficial adjunct to ART due to its potentials to reconstitute the immune system and protect the liver in HIV individuals on ART.

Player Session Rating of Perceived Exertion: A More Valid Tool Than Coaches’ Ratings to Monitor Internal Training Load in Elite Youth Female Basketball

2020 ◽  
Vol 15 (4) ◽  
pp. 548-553 ◽  
Author(s):  
Corrado Lupo ◽  
Alexandru Nicolae Ungureanu ◽  
Riccardo Frati ◽  
Matteo Panichi ◽  
Simone Grillo ◽  
...  
Keyword(s):  
Body Mass ◽  
Perceived Exertion ◽  
Team Sports ◽  
Training Load ◽  
Rating Of Perceived Exertion ◽  
Basketball Players ◽  
Mixed Effect ◽  
Maximal Intensity ◽  
Session Duration ◽  
Post Hoc

Purpose: To monitor elite youth female basketball training to verify whether players’ and coaches’ (3 technical coaches and 1 physical trainer) session rating of perceived exertion (s-RPE) has a relationship with Edwards’ method. Methods: Heart rate of 15 elite youth female basketball players (age 16.7 [0.5] y, height 178 [9] cm, body mass 72 [9] kg, body mass index 22.9 [2.2] kg·m−2) was monitored during 19 team (268 individual) training sessions (102 [15] min). Mixed effect models were applied to evaluate whether s-RPE values were significantly (P ≤ .05) related to Edwards’ data, total session duration, maximal intensity (session duration at 90–100% HRmax), type of training (ie, strength, conditioning, and technique), and whether differences emerged between players’ and coaches’ s-RPE values. Results: The results showed that there is a relationship between s-RPE and Edwards’ methods for the players’ RPE scores (P = .019) but not for those of the trainers. In addition, as expected, both players’ (P = .014) and coaches’ (P = .002) s-RPE scores were influenced by total session duration but not by maximal intensity and type of training. In addition, players’ and coaches’ s-RPE values differed (P < .001)—post hoc differences emerged for conditioning (P = .01) and technique (P < .001) sessions. Conclusions: Elite youth female basketball players are better able to quantify the internal training load of their sessions than their coaches, strengthening the validity of s-RPE as a tool to monitor training in team sports.

scholarly journals Effect of natural zeolite on biochemical and hematological parameters in blood, body mass and growth of calves

2008 ◽  
Vol 62 (3-4) ◽  
pp. 153-166 ◽  
Author(s):  
Horea Samanc ◽  
Danijela Kirovski ◽  
Milan Adamovic ◽  
Ivan Vujanac ◽  
Natalija Fratric ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Blood Serum ◽  
Body Mass ◽  
Natural Zeolite ◽  
Morphological Changes ◽  
Hematological Parameters ◽  
Hemoglobin Concentration ◽  
Control Group ◽  
Daily Growth ◽  
Group I

The work presents the results of investigations of the effect of natural zeolite (clinoptilolite type) on the degree of resumption of cloistral immunoglobulin, the value of hematological parameters and enzyme activity in blood serum (AST, ALT, and LDH), body mass, and daily growth of calves in the first three months of life. Investigations were carried out on three groups of 10 male and female calves each, with a 1:1 ratio of sexes, (control, K, and two experimental groups, I and II), of the black-and-white breed, Holstein type. All three groups of calves were fed with the usual rations (colostrum, collective cows' milk, fodder mix with 18% total proteins, and Lucerne hay).The experimental groups of calves, as opposed to the controls, received colostrums and collective cows' milk with the addition of a preparation based on natural zeolite in quantities of 5 and 10 g/l milk. The concentration of immunoglobulin G in blood serum of experimental groups of calves was significantly higher than the values of the control group (35.9?6.43 g/l in Group I; 32.5?7.39 g/l in Group II; 20.8?6.88 g/l in control group K). The results of the investigations of the values of hematological parameters (number of erythrocytes, hemoglobin concentration, and hematocrit value) do not show any digressions from the physiological values and are approximately the same in the experimental and the control groups of calves, which indicates that the examined quality of the zeolite-based preparation did not affect the degree of the resumption of iron and other oligoelements significant for erythropoietin. The data on the enzyme activity in blood serum indicate that the examined preparation does not cause any significant functional or morphological changes in the tissue of parenchymatous organs or muscles. There were no significant disorders in the health of calves of the experimental groups, while 3 calves of the control group had gastrointestinal disorders (diarrhea). Calves of experimental group I which received colostrum and collective cows' milk with an addition of 5g zeolite/l milk had a significantly greater average body mass and daily growth on the 90th day of life than calves of the control group (116.0-6.9: 105.3-6.4 kg, and 0.868:0.743 g). The addition of natural zeolite in quantities of 5 g/l colostrum or milk yields better results and has an advantage over the higher doze of zeolite of 10 g/l.

scholarly journals Association of BMI (Body Mass Index) to hemoglobin and red blood cell indices among adolescents.

2020 ◽  
Vol 27 (10) ◽  
pp. 2210-2215
Author(s):  
Saleem Ullah Abro ◽  
Quratulain Saleem ◽  
Amna Begum ◽  
Sarah Azhar ◽  
Amber Naseer ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Red Cell ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Distribution Width ◽  
Corpuscular Hemoglobin Concentration ◽  
Red Blood Cell Indices

Objectives: Hemoglobin & red blood cell indices (mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red cell distribution width) among adolescent. Study Design: Cross-Sectional study (Descriptive). Setting: Department of Physiology, Baqai Medical University (BMU) Karachi. Period: 6 months from February to August 2017. Material & Methods: A total of 500 students of MBBS, BDS, DPT with having age ranges from 18-25 years were enrolled in this study. The anthropometric measurement [height (m2) and weight (kg)] was recorded for calculation of the Body Mass Index and Complete blood count i-e Hemoglobin (Hb%), Mean Corpuscular Volume (MCV), Mean corpuscular hemoglobin (MCH), Mean corpuscular hemoglobin concentration (MCHC), Red cell distribution width (RDW) was done and calculated.  Data analysis was done on Microsoft excel & SPSS version 22.0 was used. Results: It was seen that the comparison of Hb%, MCV & RDW had no significant (p>0.001) association of study participants to different categories of Body Mass Index.  Mean corpuscular hemoglobin (MCH) (X²=28.278, p<0.001) and Mean corpuscular hemoglobin concentration (MCHC) (X²=15.659, p=0.016) were statistically significantly association with different categories of Body Mass Index. Conclusion: Mean corpuscular hemoglobin and Mean corpuscular hemoglobin concentration had statistically significant (p<0.001) association with body mass index (BMI).

scholarly journals Assessment of the Relationship Between Red Cell Distribution Width and Brucellosis: A Case-Controlled Study

2021 ◽  
Author(s):  
Li Gou ◽  
Feng Gao ◽  
Siqin Lan ◽  
Hui Guo
Keyword(s):  
Roc Curve ◽  
Hemoglobin Concentration ◽  
Red Cell Distribution Width ◽  
Controlled Study ◽  
Control Group ◽  
Red Cell ◽  
Cell Distribution ◽  
Roc Curve Analysis ◽  
Distribution Width ◽  
Markers Of Inflammation

Abstract Background: As a multisystem infectious disease, there is inflammation, which causes an increase in brucellosis. The red cell distribution width (RDW) has been identified as markers of inflammation. The present study aimed to investigate the predictive contribution value of RDW in the diagnosis of brucellosis.Methods: Medical records of 398 patients with brucellosis and 398 age-matched and gender-matched healthy controls in a single center from January 2017 to December 2019 were retrospectively reviewed.Results: The mean age of brucellosis patients was 47.1±12.9 years. The RDW levels were significantly higher in brucellosis group when compared to the control group (p < 0.001); The RDW levels were markedly lower in brucellosis male patients（14.32±2.15%）when compared to the brucellosis female patient（s 15.41±3.13%）(t= -9.56, p < 0.001). The biochemical markers of brucellosis patients included erythrocyte, hemoglobin, HCT, corpuscular volume, hemoglobin, hemoglobin concentration were all negatively correlated with RDW (r = −0.227, -0.383, -0.266, -0.253, -0.311 and -0.225, all p < 0.001). The values of hemoglobin (β coefficient = -0.084, p < 0.001), ESR (β coefficient = -0.020, p = 0.004) were significantly and independently correlated with RDW. Receiver operating characteristic (ROC) curve analysis showed that the best cutoff point for RDW in the diagnosis of brucellosis was 13.45%, which evaluated brucellosis with a sensitivity of 64.1% and a specificity of 83.9%. The area under the ROC curve for RDW was calculated as 0.80 (95% CI 0.769–0.831, P<0.001).Conclusion: This study revealed that the RDW in diagnosing brucellosis had a higher sensitivity and specificity. RDW values may be useful complementary indirect markers for the diagnosis of brucellosis.

scholarly journals ASSESSMENT OF HEMATOLOGICAL INDICES AMONG WORKERS IN SILVER JEWELRY UNITS

2017 ◽  
Vol 10 (9) ◽  
pp. 144
Author(s):  
Shalini Kv ◽  
Ayyappa Das Mp
Keyword(s):  
Tamil Nadu ◽  
Hemoglobin Concentration ◽  
Cross Sectional Study ◽  
Control Group ◽  
Differential Count ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Cross Sectional ◽  
Distribution Width ◽  
Hematological Indices

  Objective: Workers in the silver jewelry manufacturing units are exposed to heavy metals and toxic compounds during manufacturing. Hence, the present study aimed to assess the hematological indices among the workers in silver jewelry manufacturing units.Methods: A cross-sectional study was conducted in various silver jewelry manufacturing units located in Coimbatore, Tamil Nadu. One hundred and forty eight exposed and 35 unexposed (control) participants were included in this study. Their hematological indices were assessed.Results: There was significant (p<0.05) increase of serum silver (Ag) and hematological profile such as red blood cell (RBC), hematocrit, and the hemoglobin levels of exposure groups (B, C, D, and E) were found to be significantly decreased (p<0.05) compared to control group (A). There was also significant increase (p<0.05) in differential count and mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), platelet (PLT), platelet distribution width (PDW), and mean platelet volume (MPV) levels in exposed groups (B, C, D, and E) than controls (A).Conclusion: Decrease in RBC indices and the increased differential count of MCH, MCHC, PLT, PDW, and MPV levels might be due to the exposure to Ag in the jewelry units. In view of these results, it appears that ionized Ag induces hematological disturbances and the present study clearly establish that there were minimal negative effects of Ag exposure on hematological indices.

Eccentric resistance training increases and retains maximal strength, muscle endurance, and hypertrophy in trained men

2016 ◽  
Vol 41 (11) ◽  
pp. 1184-1189 ◽  
Author(s):  
Giuseppe Coratella ◽  
Federico Schena
Keyword(s):  
Resistance Training ◽  
Body Mass ◽  
Physical Inactivity ◽  
Bench Press ◽  
Chest Circumference ◽  
Control Group ◽  
Eccentric Training ◽  
Maximal Strength ◽  
Negative Effects ◽  
Baseline Values

The aim of the present study was to evaluate the effects of different resistance training protocols on muscle strength, endurance, and hypertrophy after training and detraining. Thirty-four resistance-trained males were randomized in concentric-only (CONC), eccentric-only (ECC), traditional concentric–eccentric (TRAD) bench press resistance training or control group. The training volume was equalized among the intervention groups. Bench press of 1-repetition maximum (1RM)/body mass, maximum number of repetitions (MNR), and chest circumference were evaluated at the baseline, after 6 weeks of training, and after 6 weeks of detraining. All intervention groups reported significant 1RM/body mass increases after training (CONC baseline: 1.04 ± 0.06, post-training: 1.12 ± 0.08, p < 0.05; ECC baseline: 1.08 ± 0.04, post-training: 1.15 ± 0.05, p < 0.05; TRAD baseline: 1.06 ± 0.08, post-training: 1.11 ± 0.10, p < 0.05). After detraining, only ECC retained 1RM/body mass above the baseline (1.17 ± 0.07, p < 0.05), while CONC and TRAD returned to baseline values. Only ECC improved and retained MNR (baseline: 22 ± 3; post-training: 25 ± 3, and post-detraining: 25 ± 4, p < 0.05 compared with baseline) and chest circumference (baseline: 98.3 ± 2.4 cm, post-training: 101.7 ± 2.2 cm and post-detraining: 100.7 ± 2.3 cm. p < 0.05 compared with baseline), while no significant changes occurred in both CONC and TRAD. The incorporation of eccentric training can be recommended for counteracting the negative effects of detraining or forced physical inactivity.

ZINC IN THE RATIONS OF CALVES

2019 ◽  
Keyword(s):  
Body Mass ◽  
Test Group ◽  
Hair Follicles ◽  
Control Group ◽  
Albumin Concentration ◽  
Zinc Compounds ◽  
Entire Duration ◽  
Zinc Salts ◽  
Group A ◽  
Hair Cortex

According to the Tambovagrochemcenter data, zinc deficiency in animal rations exceeds 33%. To de-termine the efficiency of ration additives 3 groups of calves were formed, one of which was control and received regular feed, first test group received additional Zinc Sulphate, and second test group received additional Zinc Bioplex. To assess the results, we take into account the following values: chemical com-position and nutritional values of the feed, body mass value, amount of immunoglobulins in blood, bio-chemical and hematological values of blood, morphological values of fur and skin. Noticeable results were achieved in 4 months, with first and second test groups receiving accordingly 3,15% and 6,13% more body mass increase over the control group. A tendency towards higher albumin concentration in both test groups was noted, and calves of the second test group had higher amounts of hemoglobin and higher concentrations of it per erythrocyte. In samples of epidermis and hairs of the second test group the papillary layer was well developed, with the amount of hair and hair follicles exceeding 7 in the field of view, with the thickness of hairs being at least 70 μm. Inner papilla of hair contained 6 to 8 layers of hair, thickness of awn hairs reaching 80-90 μm, down hairs reaching 40 μm, with the hair cortex making up more than 80% of the hair thickness. Thus, introducing zinc salts and chelated zinc compounds to the milk-fed calves’ ration, has resulted in monetary profit increases over the control group by 255,0 and 612,0 roubles accordingly. By all researched values, the highest results were reached from adding zinc bioplex with approximately 360 mg added per animal for the entire duration of the growth process.

Clinical Impact of Co-medication of Levetiracetam and Clobazam with Proton Pump Inhibitors: A Drug Interaction Study

2020 ◽  
Vol 21 (2) ◽  
pp. 126-131
Author(s):  
Bhuvanachandra Pasupuleti ◽  
Vamshikrishna Gone ◽  
Ravali Baddam ◽  
Raj Kumar Venisetty ◽  
Om Prakash Prasad
Keyword(s):  
Plasma Concentration ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Plasma Concentrations ◽  
Control Group ◽  
Drug Concentrations ◽  
Significant Difference ◽  
Post Hoc ◽  
Hydrolysis Of ◽  
Cytochrome P 450

Background: Clobazam (CLBZ) metabolized primarily by Cytochrome P-450 isoenzyme CYP3A4 than with CYP2C19, Whereas Levetiracetam (LEV) is metabolized by hydrolysis of the acetamide group. Few CYP enzymes are inhibited by Proton Pump Inhibitors (PPIs) Pantoprazole, Esomeprazole, and Rabeprazole in different extents that could affect drug concentrations in blood. The aim of the present study was to evaluate the effect of these PPIs on the plasma concentrations of LEV and CLBZ. Methods: Blood samples from 542 patients were included out of which 343 were male and 199 were female patients and were categorized as control and test. Plasma samples analyzed using an HPLC-UV method. Plasma concentrations were measured and compared to those treated and those not treated with PPIs. One way ANOVA and games Howell post hoc test used by SPSS 20 software. Results: CLBZ concentrations were significantly 10 folds higher in patients treated with Pantoprazole (P=0.000) and 07 folds higher in patients treated with Esmoprazole and Rabeprazole (P=0.00). Whereas plasma concentration of LEV control group has no statistical and significant difference when compared to pantoprazole (P=0.546) and with rabeprazole and esomeprazole was P=0.999. Conclusion: The effect of comedication with PPIs on the plasma concentration of clobazam is more pronounced for pantoprazole to a greater extent when compared to esomeprazole and rabeprazole. When pantoprazole is used in combination with clobazam, dose reduction of clobazam should be considered, or significance of PPIs is seen to avoid adverse effects.

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