Creatine supplementation does not augment muscle carnosine content in type 2 diabetic patients

2011 ◽  
Vol 36 (5) ◽  
pp. 764-767 ◽  
Author(s):  
Bruno Gualano ◽  
Rebeca Lugaresi ◽  
Vitor Painelli de Salles ◽  
Andréia Cristina Carrenho Queiroz ◽  
Guilherme Artioli ◽  
...  
Keyword(s):  
Creatine Supplementation ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Muscle Carnosine ◽  
1H Mrs ◽  
Double Blind ◽  
To Receive ◽  
Type 2 Diabetic ◽  
Blind Fashion

We examined whether creatine supplementation affects muscle carnosine content in type 2 diabetic patients. Subjects were randomly assigned to receive either creatine (5 g·day–1) or placebo in a double-blind fashion. At baseline and after 12 weeks, carnosine content was evaluated in gastrocnemius and soleus muscles by using a 1H-MRS technique. No changes were found in gastrocnemius (p = 0.81) and soleus (p = 0.85). We concluded that creatine supplementation does not augment muscle carnosine content in type 2 diabetic patients.

Erratum: Creatine supplementation does not augment muscle carnosine content in type 2 diabetic patients

2012 ◽  
Vol 37 (4) ◽  
pp. 809-809
Author(s):  
Bruno Gualano ◽  
Rebeca Lugaresi ◽  
Vitor de Salles Painelli ◽  
Andréia Cristina Carrenho Queiroz ◽  
Guilherme Artioli ◽  
...  
Keyword(s):  
Creatine Supplementation ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Muscle Carnosine ◽  
Type 2 Diabetic

SYMPHYTUM OFFICINALE IN THE TREATMENT OF PLANTAR KERATOSIS IN DIABETIC PATIENTS: DOUBLE BLIND RANDOMIZED CLINICAL TRIAL

2021 ◽  
pp. 62-64
Author(s):  
Beatriz Bertolaccini Martínez ◽  
Elisa Coutinho Moura
Keyword(s):  
Clinical Trial ◽  
Salicylic Acid ◽  
Statistical Analysis ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
Before And After ◽  
Type 2 Diabetic

PURPOSE: To compare the efcacy between SO and salicylic acid SA in the treatment of plantar keratosis of diabetic patients. METHODS: Randomized, double-blind clinical trial, with 47 type 2 diabetic patients, both sexes and with plantar keratosis. Patients were randomized into 2 groups: G1 (n = 48; treated with 15% SO extract) and G2 (n = 46; treated with 10% AS). The feet were photographed before (D0) and after the treatment (D30) and keratosis areas were measured using the Image J software. For each patient, a lesion in each foot was analyzed. The results were expressed by median. In the statistical analysis, the Wilcoxin test was used to compare the lesion areas before and after treatments and the Mann-Whitney test was used to compare the regression of the lesion areas between the two groups. P <0.05 was adopted. RESULTS: G1 (D0 = 2 8.156 vs D30 = 2.226; p <0.0001) and G2 (D0 = 4.835 vs D30 = 2.059; p <0.0001) showed a difference between the areas (cm ) of the keratosis, 2 before and after the treatment. There was a difference in the regression of the areas (cm ) of keratosis, between G1 and G2, respectively (4.540 vs 1.171, p <0.0001). CONCLUSION: Symphytum ofcinale proved to be more effective than Salicylic Acid in the treatment of plantar keratosis in diabetic patients.

scholarly journals Does High-Dose Metformin Cause Lactic Acidosis in Type 2 Diabetic Patients after CABG Surgery? A Double Blind Randomized Clinical Trial

2011 ◽  
Vol 6 (1) ◽  
pp. hi.2011.e8 ◽  
Author(s):  
Afshin Gholipour Baradari ◽  
Mohammad Reza Habibi ◽  
Hadi Darvishi Khezri ◽  
Mohsen Aarabi ◽  
Mohammad Khademloo ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Lactic Acidosis ◽  
Randomized Clinical Trial ◽  
Diabetic Patients ◽  
High Dose ◽  
Type 2 Diabetic Patients ◽  
Double Blind ◽  
Cabg Surgery ◽  
Type 2 Diabetic

scholarly journals Effects of a Flaxseed-Derived Lignan Supplement in Type 2 Diabetic Patients: A Randomized, Double-Blind, Cross-Over Trial

PLoS ONE ◽  
2007 ◽  
Vol 2 (11) ◽  
pp. e1148 ◽  
Author(s):  
An Pan ◽  
Jianqin Sun ◽  
Yanqiu Chen ◽  
Xingwang Ye ◽  
Huaixing Li ◽  
...  
Keyword(s):  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Double Blind ◽  
Type 2 Diabetic
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