Monitoring muscle oxygenation after eccentric exercise-induced muscle damage using near-infrared spectroscopy

2008 ◽  
Vol 33 (4) ◽  
pp. 743-752 ◽  
Author(s):  
Sirous Ahmadi ◽  
Peter J. Sinclair ◽  
Nasim Foroughi ◽  
Glen M. Davis
Keyword(s):  
Blood Flow ◽  
Oxygen Consumption ◽  
Infrared Spectroscopy ◽  
Oxygen Uptake ◽  
Oxygen Saturation ◽  
Eccentric Exercise ◽  
Near Infrared ◽  
Muscle Blood Flow ◽  
Muscle Oxygenation ◽  
Muscle Oxygen

Eccentric exercise (EE), a common type of muscular activity whereby muscles lengthen and contract simultaneously, is associated with higher levels of force but may also evoke muscle damage. We investigated the hypothesis that unaccustomed EE might impair muscle oxygenation and muscle blood flow in healthy adults. Ten healthy males performed a bout of 70 maximal eccentric contractions of the elbow flexors. Before and after EE on day 1 and over the next 6 days, maximum voluntary isometric torque (MVT), serum creatine kinase (CK), and the changes in muscle oxygen saturation, blood flow, and oxygen uptake (using near-infrared spectroscopy) within the biceps brachii were assessed. MVT decreased, whereas muscle soreness and CK increased after EE (p < 0.05). Mean resting oxygen saturation increased by 22% after acute EE, and remained elevated by 5%–9% for the following 6 days. During isometric contractions, significant decreases were observed in oxygen desaturation and re-saturation kinetics after EE and these declines were also significantly prevalent over the following 6 days. Both muscle blood flow and oxygen uptake increased significantly after acute EE, but recovered on the next day. This study revealed some prolonged alterations in muscle oxygenation at rest and during exercise after EE, which might be due to a decrease in muscle oxygen consumption, an increase in oxygen delivery, and (or) a combination of both. However, both oxygen consumption and blood flow recovered within 24 h after the eccentric exercise session, and therefore, the reason(s) for the changes in tissue oxygen saturation remain unknown.

Reproducibility of near-infrared spectroscopy measurements of oxidative function and postexercise recovery kinetics in the medial gastrocnemius muscle

2014 ◽  
Vol 39 (5) ◽  
pp. 521-529 ◽  
Author(s):  
William M. Southern ◽  
Terence E. Ryan ◽  
Mary A. Reynolds ◽  
Kevin McCully
Keyword(s):  
Blood Flow ◽  
Oxygen Consumption ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Plantar Flexion ◽  
Medial Gastrocnemius ◽  
Muscle Oxygen ◽  
Oxidative Function ◽  
Mitochondrial Capacity

The purpose of this study was to assess the reproducibility of resting blood flow, resting oxygen consumption, and mitochondrial capacity in skeletal muscle using near-infrared spectroscopy (NIRS). We also determined the influence of 2 exercise modalities (ergometer and rubber exercise bands) on the NIRS measurements. Fifteen young, healthy participants (5 female, 10 male) were tested on 2 nonconsecutive occasions within an 8-day period. The NIRS device was placed on the medial gastrocnemius. Venous and arterial occlusions were performed to obtain blood flow and oxygen consumption. A series of repeated arterial occlusions was used to measure the recovery kinetics of muscle oxygen consumption after ∼7–10 s of voluntary plantar flexion exercise. Resting blood flow had mean coefficients of variation (CV) of 42% and 38% for bands and ergometer, respectively, and resting metabolism had mean CVs of 17% and 12% for bands and ergometer, respectively. The recovery time constant of oxygen consumption (day 1 bands and ergometer: 23.2 ± 3.7 s, 27.6 ± 6.5 s, respectively; day 2 bands and ergometer: 25.5 ± 5.4 s, 25.0 ± 4.9 s, respectively) had mean CVs of 10% and 11% for bands and ergometer, respectively. We conclude that measurements of oxygen consumption and mitochondrial capacity using NIRS can be obtained with good reproducibility.

scholarly journals Reliability of muscle blood flow and oxygen consumption response from exercise using near-infrared spectroscopy

2017 ◽  
Vol 103 (1) ◽  
pp. 90-100 ◽  
Author(s):  
Adam A. Lucero ◽  
Gifty Addae ◽  
Wayne Lawrence ◽  
Beemnet Neway ◽  
Daniel P. Credeur ◽  
...  
Keyword(s):  
Blood Flow ◽  
Oxygen Consumption ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Muscle Blood Flow

scholarly journals Calf muscle blood flow and oxygen consumption measured with near-infrared spectroscopy during venous occlusion

1999 ◽  
Author(s):  
Lelia A. Paunescu ◽  
Claudia Casavola ◽  
Maria-Angela Franceschini ◽  
Sergio Fantini ◽  
Lew Winter ◽  
...  
Keyword(s):  
Blood Flow ◽  
Oxygen Consumption ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Muscle Blood Flow ◽  
Venous Occlusion ◽  
Calf Muscle

Tissue Oxygenation by Near-Infrared Spectroscopy and Muscle Blood Flow During Isometric Contractions of the Forearm

1999 ◽  
Vol 24 (3) ◽  
pp. 216-230 ◽  
Author(s):  
Andrew Hicks ◽  
Stuart Mcgill ◽  
Richard L. Hughson
Keyword(s):  
Blood Flow ◽  
Infrared Spectroscopy ◽  
Doppler Ultrasound ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Tissue Oxygenation ◽  
Muscle Blood Flow ◽  
Venous Blood ◽  
Muscle Oxygenation ◽  
Isometric Contractions

The relationship between tissue oxygenation measured by near-infrared spectroscopy (NIRS) and forearm muscle blood flow (FBF) measured by Doppler ultrasound was tested during isometric contractions at 10 and 30% maximal voluntary contraction (MVC) under conditions of normoxia and hypoxia (14% inspired O2). Six subjects maintained contractions at 10% MVCfor 5 min and at 30% for 2 min in both gas conditions. FBF was elevated during exercise at 10% MVC in hypoxia compared to normoxia, but there was no further increase in flow at 30% MVC. Median power frequency calculations from electromyographic recordings suggested progressive development of fatigue throughout both 10 and 30% MVC contractions. NIRS indicated no change in muscle oxygenation at 10% MVC, but deep venous blood O2 saturation was reduced in normoxia and more so in hypoxia. At 30% MVC, both NIRS and venous O2 saturation were reduced, with no effect of hypoxia on the NIRS signal. While NIRS might provide an indication of muscle oxygenation during isometric exercise, the conflicting findings for NIRS and direct venous blood sampling at 10 vs. 30% MVC suggest caution in the application of this noninvasive technique. Key words: exercise, Doppler ultrasound, venous blood. O2 saturation, hemoglobin

Human respiratory muscle blood flow measured by near-infrared spectroscopy and indocyanine green

2008 ◽  
Vol 104 (4) ◽  
pp. 1202-1210 ◽  
Author(s):  
Jordan A. Guenette ◽  
Ioannis Vogiatzis ◽  
Spyros Zakynthinos ◽  
Dimitrios Athanasopoulos ◽  
Maria Koskolou ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cardiac Output ◽  
Infrared Spectroscopy ◽  
Respiratory Muscle ◽  
Near Infrared ◽  
Vastus Lateralis ◽  
Muscle Blood Flow ◽  
Work Of Breathing ◽  
Dilution Method ◽  
Transdiaphragmatic Pressure

Measurement of respiratory muscle blood flow (RMBF) in humans has important implications for understanding patterns of blood flow distribution during exercise in healthy individuals and those with chronic disease. Previous studies examining RMBF in humans have required invasive methods on anesthetized subjects. To assess RMBF in awake subjects, we applied an indicator-dilution method using near-infrared spectroscopy (NIRS) and the light-absorbing tracer indocyanine green dye (ICG). NIRS optodes were placed on the left seventh intercostal space at the apposition of the costal diaphragm and on an inactive control muscle (vastus lateralis). The primary respiratory muscles within view of the NIRS optodes include the internal and external intercostals. Intravenous bolus injection of ICG allowed for cardiac output (by the conventional dye-dilution method with arterial sampling), RMBF, and vastus lateralis blood flow to be quantified simultaneously. Esophageal and gastric pressures were also measured to calculate the work of breathing and transdiaphragmatic pressure. Measurements were obtained in five conscious humans during both resting breathing and three separate 5-min bouts of constant isocapnic hyperpnea at 27.1 ± 3.2, 56.0 ± 6.1, and 75.9 ± 5.7% of maximum minute ventilation as determined on a previous maximal exercise test. RMBF progressively increased (9.9 ± 0.6, 14.8 ± 2.7, 29.9 ± 5.8, and 50.1 ± 12.5 ml·100 ml−1·min−1, respectively) with increasing levels of ventilation while blood flow to the inactive control muscle remained constant (10.4 ± 1.4, 8.7 ± 0.7, 12.9 ± 1.7, and 12.2 ± 1.8 ml·100 ml−1·min−1, respectively). As ventilation rose, RMBF was closely and significantly correlated with 1) cardiac output ( r = 0.994, P = 0.006), 2) the work of breathing ( r = 0.995, P = 0.005), and 3) transdiaphragmatic pressure ( r = 0.998, P = 0.002). These data suggest that the NIRS-ICG technique provides a feasible and sensitive index of RMBF at different levels of ventilation in humans.

Effect of Climbing Speed on Pulmonary Oxygen Uptake and Muscle Oxygen Saturation Dynamics in the Finger Flexors

2021 ◽  
pp. 1-9
Author(s):  
Jan Gajdošík ◽  
Jirˇí Baláš ◽  
Dominika Krupková ◽  
Lukáš Psohlavec ◽  
Nick Draper
Keyword(s):  
Oxygen Uptake ◽  
Oxygen Saturation ◽  
Near Infrared ◽  
Cellular Level ◽  
Gas Analysis ◽  
Whole Body ◽  
Flexor Digitorum Profundus ◽  
Muscle Oxygen ◽  
Sport Climbing ◽  
Body Activity

Purpose: Although sport climbing is a self-paced whole-body activity, speed varies with climbing style, and the effect of this on systemic and localized oxygen responses is not well understood. Therefore, the aim of the present study was to determine muscle and pulmonary oxygen responses during submaximal climbing at differing speeds of ascent. Methods: Thirty-two intermediate and advanced sport climbers completed three 4-minute-long ascents of the same route at 4, 6, and 9 m·min−1 on a motorized climbing ergometer (treadwall) on separate laboratory visits. Gas analysis and near-infrared spectroscopy were used to determine systemic oxygen uptake () and muscle oxygen saturation (StO2) of the flexor digitorum profundus. Results: Increases in ascent speed of 1 m·min−1 led to increases of by 2.4 mL·kg−1·min−1 (95% CI, 2.1 to 2.8 mL·kg−1·min−1) and decreases in StO2 by −1.3% (95% CI, 1.9% to −0.7%). There was a significant interaction of climbing ability and speed for StO2 (P < .001, ). The results revealed that the decrease of StO2 was present for intermediate but not advanced climbers. Conclusions: In this study, the results suggest that demand during climbing was largely determined by climbing speed; however, the ability level of the climber appeared to mitigate StO2 at a cellular level. Coaches and instructors may prescribe climbing ascents with elevated speed to improve generalized cardiorespiratory fitness. To stimulate localized aerobic capacity, however, climbers should perhaps increase the intensity of training ascents through the manipulation of wall angle or reduction of hold size.

Noninvasive measurement of forearm blood flow and oxygen consumption by near-infrared spectroscopy

1994 ◽  
Vol 76 (3) ◽  
pp. 1388-1393 ◽  
Author(s):  
R. A. De Blasi ◽  
M. Ferrari ◽  
A. Natali ◽  
G. Conti ◽  
A. Mega ◽  
...  
Keyword(s):  
Blood Flow ◽  
Oxygen Consumption ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Healthy Subjects ◽  
Near Infrared ◽  
Forearm Blood Flow ◽  
Vascular Occlusion ◽  
Venous Occlusion ◽  
The Subject

We applied near-infrared spectroscopy (NIRS) for the simultaneous measurement of forearm blood flow (FBF) and oxygen consumption (VO2) in the human by inducing a 50-mmHg venous occlusion. Eleven healthy subjects were studied both at rest and after hand exercise during vascular occlusion. FBF was also measured by strain-gauge plethysmography. FBF measured by NIRS was 1.9 +/- 0.8 ml.100 ml-1.min-1 at rest and 8.2 +/- 2.9 ml.100 ml-1.min-1 after hand exercise. These values showed a correlation (r = 0.94) with those obtained by the plethysmography. VO2 values were 4.6 +/- 1.3 microM O2 x 100 ml-1.min-1 at rest and 24.9 +/- 11.2 microM O2 x 100 ml-1.min-1 after hand exercise. The scatter of the FBF and VO2 values showed a good correlation between the two variables (r = 0.93). The results demonstrate that NIRS provides the particular advantage of obtaining the contemporary evaluation of blood flow and VO2, allowing correlation of these two variables by a single maneuver without discomfort for the subject.

scholarly journals Vastus lateralis oxygenation during prolonged cycling in healthy males

2006 ◽  
Vol 31 (1) ◽  
pp. 48-55 ◽  
Author(s):  
Kotaro Kawaguchi ◽  
Yukiko Hayashi ◽  
Kiyokazu Sekikawa ◽  
Mitsuru Tabusadani ◽  
Tsutomu Inamizu ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Oxygen Uptake ◽  
Blood Volume ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Vastus Lateralis ◽  
Muscle Oxygenation ◽  
Cardiovascular Drift ◽  
Systemic Oxygen ◽  
The Relationship

This study examined the relationship between acute cardiorespiratory and muscle oxygenation and blood volume changes during prolonged exercise. Eight healthy male volunteers (mean maximum oxygen uptake ([Formula: see text]O2max) = 41.6 ± 2.4 mL/kg/min) performed 60 min submaximal cycling at 50% [Formula: see text]O2max. Oxygen uptake ([Formula: see text]O2) was measured by indirect spirometry, cardiac output (CO) was estimated using a PortapresTM, and right vastus lateralis oxyhemoglobin/ myoglobin (oxyHb/Mb), deoxyhemoglobin/myoglobin (deoxyHb/Mb), and total hemoglobin/myoglobin (total Hb/Mb) were recorded using near-infrared spectroscopy (NIRS). After 40 min of exercise, there was a significant increase in [Formula: see text]O2 due to a significantly higher arteriovenous oxygen difference ((a - v)O2diff). After 30 min of exercise CO remained unchanged, but there was a significant decrease in stroke volume and a proportionate increase in heart rate, thus indicating the occurrence of cardiovascular drift. During the first few minutes of exercise, there was a decline in oxyHb/Mb and total Hb/Mb, whereas deoxyHb/Mb remained unchanged. Thereafter, oxyHb/Mb and total Hb/Mb increased systematically until the termination of exercise while deoxyHb/Mb declined. After 40 min of exercise, these changes were significantly different from the baseline values. There were no significant correlations between the changes in the NIRS variables and systemic [Formula: see text]O2 or mixed (a - v)O2diff during exercise. These results suggest that factors other than localized changes in muscle oxygenation and blood volume account for the increased [Formula: see text]O2 during prolonged submaximal exercise. Key words: near infrared spectroscopy, cardiovascular drift, systemic oxygen consumption.

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