Cloning, characterization, and chromosomal localization of human liver form cytochrome c oxidase subunit VIa related genes

Genome ◽  
1997 ◽  
Vol 40 (3) ◽  
pp. 325-331 ◽  
Author(s):  
Frank Merante ◽  
Mingfu Ling ◽  
Catherine Duff ◽  
Brian H. Robinson ◽  
Alessandra M. V. Duncan

The chromosomal location of human cytochrome c oxidase (COX) subunit VIa Liver (VIa-L) isoform related sequences has been determined by a combination of in situ hybridization and analysis of human–hamster somatic cell hybrid panels. COX VIa-L related sequences were present on chromosomes 6 and 12. It has been verified that at least two COX VIa-L genes are on chromosome 6, one of which is a pseudogene. In total, four COX VIa-L related sequences have been cloned and their nucleotide sequences analyzed. At least three of these sequences represent pseudogenes; their relatedness to the COX VIa-L cDNA is discussed.Key words: human, cytochrome c oxidase, chromosomal localization, COX VIa, cloning.

Genome ◽  
1997 ◽  
Vol 40 (3) ◽  
pp. 318-324 ◽  
Author(s):  
Frank Merante ◽  
Alessandra M. V. Duncan ◽  
Grant Mitchell ◽  
Catherine Duff ◽  
Joanna Rommens ◽  
...  

The chromosomal loci corresponding to human cytochrome c oxidase (COX) subunit VIIa Liver (VIIa-L) isoform genes were determined utilizing a combined approach of genomic cloning, in situ hybridization, and somatic cell hybrid genetics. In contrast to the proposal of E. Arnaudo et al. (Gene (Amst.), 119: 299–305. 1992) that COX VIIa-L sequences are located on chromosomes 4 and 14, we found that COX VIIa-L related sequences reside on chromosome 6, while an additional COX VIIa-L cross-reacting sequence (ψ-gene) was located on chromosome 4.Key words: human, cytochrome c oxidase, gene mapping, pseudogenes.


1991 ◽  
Vol 87 (3) ◽  
pp. 325-327 ◽  
Author(s):  
Jan-Willem Taanman ◽  
Anneke Y. van der Veen ◽  
Cobi Schrage ◽  
Hans de Vries ◽  
Charles H. C. M. Buys

Gene ◽  
1991 ◽  
Vol 102 (2) ◽  
pp. 229-236 ◽  
Author(s):  
Roque D. Carrero-Valenzuela ◽  
Franklin Quan ◽  
Robert Lightowlers ◽  
Nancy G. Kennaway ◽  
Michael Litt ◽  
...  

2007 ◽  
Vol 5 (1) ◽  
pp. 9-20 ◽  
Author(s):  
Scot C. Leary ◽  
Paul A. Cobine ◽  
Brett A. Kaufman ◽  
Guy-Hellen Guercin ◽  
Andre Mattman ◽  
...  

1996 ◽  
Vol 333 (1) ◽  
pp. 152-162 ◽  
Author(s):  
Nancy J. Bachman ◽  
Tony L. Yang ◽  
Jeremy S. Dasen ◽  
Robin E. Ernst ◽  
Margaret I. Lomax

1990 ◽  
Vol 1018 (2-3) ◽  
pp. 223-224 ◽  
Author(s):  
Gary Ewart ◽  
Robert Lightowlers ◽  
Yu-Zhong Zhang ◽  
V.J. Balan ◽  
Nancy Kennaway ◽  
...  

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