Organisation of the mitochondrial genome from Atlantic salmon (Salmo salar)

Genome ◽  
1989 ◽  
Vol 32 (2) ◽  
pp. 340-342 ◽  
Author(s):  
William S. Davidson ◽  
Tim P. Birt ◽  
John M. Green

A restriction map of Atlantic salmon mitochondrial DNA was constructed. The smallest XbaI fragment of the salmon mitochondrial genome was cloned and subjected to partial DNA sequence analysis. This fragment contains the genes for ATPase 6 and cytochrome oxidase III. The putative organisation of the mitochondrial genome relative to the physical map is shown.Key words: salmonid, mitochondrial DNA, restriction map, sequence analysis.

Gene ◽  
1999 ◽  
Vol 239 (2) ◽  
pp. 237-242 ◽  
Author(s):  
Carolyn D. Hurst ◽  
Sylvia E. Bartlett ◽  
William S. Davidson ◽  
Ian J. Bruce

2020 ◽  
Author(s):  
Gyamfua Afriyie ◽  
Yusong Guo ◽  
Felix K.A Kuebutornye ◽  
Christian Ayisi Larbi ◽  
Zhongduo Wang

Abstract The authors have withdrawn this preprint from Research Square


2006 ◽  
Vol 50 (2) ◽  
pp. 137-147 ◽  
Author(s):  
Jean-François Pombert ◽  
Philippe Beauchamp ◽  
Christian Otis ◽  
Claude Lemieux ◽  
Monique Turmel

1999 ◽  
Vol 277 (4) ◽  
pp. E702-E707 ◽  
Author(s):  
Sook-Bae Kim ◽  
Carolyn D. Berdanier

BHE/Cdb and Sprague-Dawley rats differ in their mitochondrial DNA sequence for the ATPase 6 (“subunit a”) gene. Base substitutions in this sequence result in the substitution of asparagine for aspartate at position 101 and the substitution of serine for leucine at position 129. Differences in sensitivity to oligomycin were observed. When the isolated F1F0-ATPase complex was studied and ATPase activity was assessed, that which was isolated from the BHE/Cdb rats was less sensitive to oligomycin inhibition than that which was isolated from the Sprague-Dawley rats. In contrast, when oxygen consumption was measured [oxygen phosphorylation (OXPHOS)] and a dose-response curve was generated with isolated mitochondria from these two strains, there was a shift to the left for the BHE/Cdb rat mitochondria. These mitochondria were more sensitive to oligomycin inhibition of OXPHOS than were mitochondria isolated from Sprague-Dawley rats. The OXPHOS results are consistent with those from human fibroblasts having either a normal or mutated ATPase 6 gene.


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