scholarly journals Stereotactic radiosurgery delivery verification using tetrazolium salt-based gel as a dosimeter

2017 ◽  
Vol 95 (8) ◽  
pp. 725-730 ◽  
Author(s):  
Michael S. Gossman ◽  
Erik J.L. Courter
Keyword(s):  
Quality Assurance ◽  
Radiation Therapy ◽  
Stereotactic Radiosurgery ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Tetrazolium Salt ◽  
Conformal Radiation Therapy ◽  
Stereotactic Radiation ◽  
End To End ◽  
Delivery Accuracy

The recently made available ClearView® tetrazolium salt-based gel dosimeter, encapsulated in a vial, was tested to determine feasibility in use as an end-to-end dosimeter for stereotactic radiosurgery commissioning and quality assurance. A fabricated adaptor enabled direct attachment of the gel vial lid to a rod extension. The rod was inserted into a water-filled head phantom at the open neck location and locked into position. Once quality assurance testing of the linear accelerator was completed, a stereotactic plan was deployed. Optical scanning software enabled a direct comparison of the measured positional isocenter and dose distribution to the intended plan. Delivery accuracy was verified as line-dose profile plots of measured data coincide with the planned dose location and distribution. It has been demonstrated here that ClearView® gel contained in a vial is a suitable dosimeter for verifying stereotactic radiation therapy delivery accuracy. The end-to-end testing provided is geared to work identically for any small field study, including stereotactic radiosurgery and radiotherapy, volumetric modulated arc therapy, intensity modulated radiation therapy, and three-dimensional conformal radiation therapy.

Patterns of radiation therapy technology use in the treatment of bone metastases.

2016 ◽  
Vol 34 (26_suppl) ◽  
pp. 211-211
Author(s):  
Matthew Chan ◽  
Robert Anton Olson ◽  
Shilo Lefresne ◽  
Michael R. McKenzie
Keyword(s):  
British Columbia ◽  
Radiation Therapy ◽  
Bone Metastases ◽  
Technology Use ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Conformal Radiation Therapy ◽  
Lung Cancers ◽  
Significant Difference ◽  
3D Crt

211 Background: In recent years, there has been a transition from two-dimensional radiation therapy (2DRT) planning towards more advanced techniques such as three-dimensional conformal radiation therapy (3D-CRT), volumetric modulated arc therapy (VMAT), and stereotactic body radiation therapy (SBRT). Our study aim was to analyze these trends in the treatment of bone metastases. Methods: All patients aged 18 and older who had received palliative intent RT for bone metastases between 2009-2014 and referred to any 1 of 6 regional cancer centers in British Columbia, Canada were reviewed. Summary statistics were used to describe radiation technique patterns. Logistic regression modeling was used to assess the influence of demographic, clinical, and health services variables on receipt of types of RT. Results: We identified 8,059 patients and 15,832 courses of RT; overall, 97.9% of courses were achieved by 2DRT and 2.1% by 3D-CRT, VMAT, or SBRT. Despite the low overall use of advanced techniques, its use was significantly higher in all subsequent years compared to 2009 (p < 0.05 for all years). The median age for patients treated with 2DRT was 67.0 (19-99) versus 66.0 years (19-93) for advanced techniques. There did not appear to be a statistically significant difference in age at the time of treatment start (OR 0.99; 95% CI 0.981-1.00, p < 0.05). Compared to lung cancers, thyroid (OR 9.9; 95% CI 5.197-18.724, p < 0.001) and kidney cancers (OR 3.9; 95% CI 2.508-5.911, p < 0.001) were significantly more likely to be treated with advanced techniques, while breast (OR 0.90; 95% CI 0.621-1.306, p = 0.58) and prostate cancers (OR 0.93; 95% CI 0.613-1.410, p = 0.73) were not any more likely. Compared to the Vancouver center, all other treatment centers in the province were utilizing advanced techniques less frequently. Patients were also more likely to complete RT with 2DRT than with advanced techniques (98.3% versus 95.8%, p < 0.05). Conclusions: The vast majority of treatment of bone metastases is still done by 2DRT in British Columbia. Despite these overall statistics though, a trend towards increasing use of more advanced techniques was observed.

Comparison of dosimetry parameters of three-dimensional conformational radiation therapy and volumetric modulated arc therapy on the example of treatment of a patient with salivary gland adenocarcinoma

2021 ◽  
Vol 59 (1) ◽  
pp. 25-30
Author(s):  
A. Rakhimov ◽  
M. Zekebayev ◽  
A. Kuatbek ◽  
V. Dyachkov
Keyword(s):  
Radiation Therapy ◽  
Salivary Gland ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Optimal Choice ◽  
International Standards ◽  
Salivary Gland Cancer ◽  
Conformal Radiation Therapy ◽  
Dose Load ◽  
Arc Therapy

An optimal choice of radiation therapy method is the main prerequisite for successful completion of treatment. Continuous analysis of radiation therapy methods’ advantages and comparing their parameters and dose load in typical cases will increase the treatment efficacy and reduce the unavoidable load on critical organs. The purpose was to check the plans of treatment by volumetric modulated arc therapy (VMAT) and three-dimensional conformal radiation therapy (3D-CRT) methods, make their comparison and identify the advantages using an example of a treatment design for a patient treated at the Daily Radiotherapy Hospital of the Kazakh Institute of Oncology and Radiology (Almaty, Kazakhstan). Results: The presented illustrations of the process planning and the numerical analysis of the dose load on critical organs show VMAT advantages for radiation therapy of salivary gland cancer: optimal coverage, sparing load on critical organs and healthy tissues, gradient decay at the borders of the neoplasm. Conclusion: The variability of radiation therapy methods ensures the most acceptable coverage that keeps the dose load within international standards’ ranges. Mastering these methods will improve the effectiveness of radiation therapy for various cancer cases

scholarly journals Total Workload for Radioactive Facilities with Volumetric Modulated Arc Treatment

2019 ◽  
Vol 7 (3) ◽  
Author(s):  
Juraci Passos Reis ◽  
Victor Gabriel Alves ◽  
Leandro Rodrigues Fairbanks
Keyword(s):  
Radiation Therapy ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Intensity Modulated Radiation Therapy ◽  
Conformal Radiation Therapy ◽  
Average Value ◽  
A Value ◽  
Shielding Design ◽  
Total Workload ◽  
Clinical Workload

In recent years, there have been major changes in radiotherapy, particularly in dose delivery for treatments using the techniques of Three-Dimensional Conformal Radiation Therapy (3D-CRT), Intensity-Modulated Radiation Therapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT). However, in the literature, no workload results for radiation therapy treatments performed exclusively with the VMAT technique were found. In this study, a new workload and a new VMAT factor will be proposed. For such, patient data originating from management and planning systems were acquired, such as dose values, monitor units, numbers of arcs per patient and number of hypofractionated treatments. The average clinical workload values for conventional treatments were 328 Gy/week, resulting in a VMAT factor of 1.97; similarly, for hypofractionated treatments, the clinical workload was 33Gy/week and the VMAT factor was 1.54. The total workload has a value of 596 Gy/week, less than the value used in the facility shielding design, 1250 Gy/week, and the average value of VMAT factor for conventional and hypofractionated treatments showed that a smaller amount of C should be used at facilities that perform exclusive VMAT treatment.

scholarly journals Influence of respiratory movement during regional nodal irradiation after mastectomy for breast cancer: an experimental study

2020 ◽  
Author(s):  
Hosang Jeon ◽  
Yongkan Ki ◽  
Dong Woon Kim ◽  
Wontaek Kim ◽  
Jiho Nam ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Absorbed Dose ◽  
Respiratory Movement ◽  
Radiochromic Film ◽  
Organ Protection ◽  
Conformal Radiation Therapy ◽  
Dose Errors ◽  
3D Crt

Abstract Background This study aimed to evaluate the dosimetric consequences of respiratory movement in postmastectomy radiation therapy (PMRT) including internal mammary nodes (IMNs) between volumetric modulated arc therapy (VMAT) and three-dimensional conformal radiation therapy (3D-CRT).Methods An anthropomorphic phantom was used to mimic the chest anatomy of a patient who had undergone mastectomy. Two types of absorbed dose measurements were adopted; a radiochromic film was inserted into a gap between phantom slices at the level of the second IMN and three glass rod dosimeters were placed at the first IMN (IM), chest wall (CW), and left anterior descending (LAD) artery. Respiratory movements with amplitudes of 5 mm (R05) and 10 mm (R10) were simulated using a dynamic platform combined with a motorized jack. To evaluate dose errors caused by respiratory movement, the measured data in the presence and absence of respiratory movement were compared.Results At IM, dose errors were − 2.8% (R05) and − 6.2% (R10) for 3D-CRT and − 4.9% (R05) and − 8.5% (R10) for VMAT. The dose errors in CW were − 0.5% (R05) and − 6.0% (R10) for 3D-CRT and − 1.9% (R05) and − 5.3% (R10) for VMAT. The LAD doses showed very small absolute values. According to film measurements, dose errors of IMN were similar between 3D-CRT and VMAT, but the dose error of the lung was higher in 3D-CRT. The gamma pass rates of VMAT (97% at R05; 88% at R10) were higher than those of 3D-CRT (74% at R05; 59% at R10).Conclusions If the patient maintained shallow to normal breathing, PMRT including IMNs could be implemented with acceptable accuracy. In particular, it was possible to maintain the advantages of VMAT, which enabled high-target coverage and normal organ protection.

scholarly journals Comparison of dosimetry parameters of three-dimensional conformational radiation therapy and volumetric modulated arc therapy on the example of treatment of a patient with salivary gland adenocarcinoma

2021 ◽  
Vol 59 (1) ◽  
pp. 25-30
Author(s):  
Adil Rakhimov ◽  
Miras Zekebayev ◽  
Aray Kuatbek ◽  
Vyacheslav Dyachkov
Keyword(s):  
Radiation Therapy ◽  
Salivary Gland ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Optimal Choice ◽  
International Standards ◽  
Salivary Gland Cancer ◽  
Conformal Radiation Therapy ◽  
Dose Load ◽  
Arc Therapy

Relevance: An optimal choice of radiation therapy method is the main prerequisite for successful completion of treatment. Continuous analysis of radiation therapy methods’ advantages and comparing their parameters and dose load in typical cases will serve to increase the treatment efficacy and reduce the unavoidable load on critical organs. Purpose: To check the plans of treatment by volumetric modulated arc therapy (VMAT) and three-dimensional conformal radiation therapy (3D-CRT) methods, make their comparison, and identify the advantages using an example of a treatment design for a patient treated at the Daily Radiotherapy Hospital of the Kazakh Institute of Oncology and Radiology (Almaty, Kazakhstan). Results: The presented illustrations of the process planning and the numerical analysis of the dose load on critical organs show VMAT advantages for radiation therapy of salivary gland cancer: optimal coverage, sparing load on critical organs and healthy tissues, gradient decay at the borders of the neoplasm. Conclusion: The variability of radiation therapy methods ensures the most acceptable coverage that keeps the dose load within international standards’ ranges. Mastering these methods will improve the effectiveness of radiation therapy for various cancer cases.

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