THE INFLUENCE OF SOME HORMONAL, DIETARY, AND TUMOR FACTORS ON LIVER CATALASE ACTIVITY IN RATS

1953 ◽  
Vol 31 (4) ◽  
pp. 307-314
Author(s):  
R. W. Begg ◽  
T. E. Dickinson ◽  
A. V. White
Keyword(s):  
Catalase Activity ◽  
Body Growth ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Growth Disturbance ◽  
Liver Size ◽  
Tumor Bearing ◽  
Low Protein ◽  
Nonspecific Factors

Liver catalase activity can be reduced by the administration of cortisone or stilboestrol and by the production of anemia, as well as by the presence of a tumor in the host. All of these factors cause a disturbance of body growth. However, interference with growth produced by adrenalectomy or low protein diet is not associated with loss of liver catalase activity. The loss of liver catalase activity in tumor-bearing rats is associated frequently with an increase in liver size. But rats with large tumors may have small livers and still demonstrate the drop in catalase activity. It is suggested that the loss of liver catalase activity in tumor-bearing rats is not due to body growth disturbance or liver hypertrophy, and is produced in excess of such nonspecific factors as adrenal stimulation.

THE RELATION OF DIET, HORMONES, AND TUMORS TO THE ACTIVITY OF LIVER XANTHINE OXIDASE IN THE RAT

1957 ◽  
Vol 35 (11) ◽  
pp. 881-887 ◽  
Author(s):  
A. F. Burton ◽  
R. W. Begg
Keyword(s):  
Enzyme Activity ◽  
Xanthine Oxidase ◽  
Adenosine Deaminase ◽  
Hormonal Control ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Purine Catabolism ◽  
Tumor Bearing ◽  
Low Protein ◽  
Enzyme Formation

The activity of liver xanthine oxidase and of adenosine deaminase in rats was reduced to a low value when the animals were fed a low protein diet. This did not occur in tumor-bearing animals on the same diet. The maintenance of enzyme activity in the tumor-bearing animals could not be attributed to induced enzyme formation or to alteration in hormonal control, but may be associated with an increase in purine catabolism.

THE RELATION OF DIET, HORMONES, AND TUMORS TO THE ACTIVITY OF LIVER XANTHINE OXIDASE IN THE RAT

1957 ◽  
Vol 35 (1) ◽  
pp. 881-887
Author(s):  
A. F. Burton ◽  
R. W. Begg
Keyword(s):  
Enzyme Activity ◽  
Xanthine Oxidase ◽  
Adenosine Deaminase ◽  
Hormonal Control ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Purine Catabolism ◽  
Tumor Bearing ◽  
Low Protein ◽  
Enzyme Formation

The activity of liver xanthine oxidase and of adenosine deaminase in rats was reduced to a low value when the animals were fed a low protein diet. This did not occur in tumor-bearing animals on the same diet. The maintenance of enzyme activity in the tumor-bearing animals could not be attributed to induced enzyme formation or to alteration in hormonal control, but may be associated with an increase in purine catabolism.

Hepatic Ultrastructure Changes Induced by Lithocholic Acid

1967 ◽  
Vol 25 ◽  
pp. 162-163 ◽  
Author(s):  
F. G. Zaki
Keyword(s):  
Endoplasmic Reticulum ◽  
Lithocholic Acid ◽  
Smooth Endoplasmic Reticulum ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Electron Microscopic ◽  
Hydropic Degeneration ◽  
Hepatic Cells ◽  
Low Protein ◽  
Microscopic Studies

Addition of lithocholic acid (LCA), a naturally occurring bile acid in mammals, to a low protein diet fed to rats induced marked inflammatory reaction in the hepatic cells followed by hydropic degeneration and ductular cell proliferation. These changes were accompanied by dilatation and hyperplasia of the common bile duct and formation of “gallstones”. All these changes were reversible when LCA was withdrawn from the low protein diet except for the hardened gallstones which persisted.Electron microscopic studies revealed marked alterations in the hepatic cells. Early changes included disorganization, fragmentation of the rough endoplasmic reticulum and detachment of its ribosomes. Free ribosomes, either singly or arranged in small clusters were frequently seen in most of the hepatic cells. Vesiculation of the smooth endoplasmic reticulum was often encountered as early as one week after the administration of LCA (Fig. 1).

Economic Effects of Treatment of Chronic Kidney Disease with Low-Protein Diet

2013 ◽  
Author(s):  
Francesco Saverio Mennini ◽  
Simone Russo ◽  
Andrea Marcellusi ◽  
Giuseppe Quintaliani ◽  
Denis Fouque
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Economic Effects ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Low Protein

scholarly journals PSIV-6 Effect of a Phytogenic Water Additive on Growth Performance, Blood Metabolites and Gene Expression of Amino Acids Transporters in Nursery Pigs Fed with Low Protein Diets

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 281-282
Author(s):  
Cedrick N Shili ◽  
Mohammad Habibi ◽  
Julia Sutton ◽  
Jessie Barnes ◽  
Jacob Burchkonda ◽  
...  
Keyword(s):  
Gene Expression ◽  
Amino Acids ◽  
Growth Performance ◽  
Mrna Abundance ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Blood Calcium ◽  
Low Protein ◽  
Protein Diets ◽  
Standard Protein

Abstract Moderately low protein (MLP) diets can help decrease nutrient excretion from the swine production. However, MLP diets negatively impact growth performance. We hypothesized that supplementing MLP diets with phytogenics may reduce the negative effects of these diets on growth. The objective of this study was to investigate the effect of a phytogenic water additive (PWA; Herbanimal®) on growth performance, blood metabolite and gene expression of amino acids transporters in pigs fed with MLP diets. Forty-eight weaned barrows were allotted to six dietary treatments (n = 8) for 4 weeks: >CON-NS: standard protein diet-no PWA; CON-LS: standard protein diet-low PWA dose (4 ml/L); CON-HS: standard protein diet-high PWA dose (8 ml/L); LP-NS: low protein diet-no PWA; LP-LS: low protein diet-low PWA dose (4 ml/L); LP-HS: low protein diet- high PWA dose (8 ml/L). Feed intake and body weight were recorded daily and weekly, respectively. At week 4, blood and tissue samples were collected and analyzed for metabolites using a chemistry analyzer and amino acid transporters using qPCR, respectively. The data were analyzed by univariate GLM (SPSS®) and the means were separated using paired Student’s t-test corrected by Benjamini-Hochberg. Pigs fed CON-HS improved the average daily gain and serum calcium and phosphorus concentrations compared to CON-NS. Pigs fed LP-LS had higher serum phosphorus and blood urea nitrogen compared to the pigs fed with LP-NS. The mRNA abundance of SLC7A11 in the jejunum was lower in CON-LS and CON-HS compared to CON-NS. Additionally, mRNA abundance of SLC6A19 in the jejunum of pigs fed with LP-LS was higher compared to LP-NS and lower in CON-HS relative to pigs fed with CON-LS. In conclusion, PWA improved the growth performance of pigs fed standard protein diets but not low protein diets. Further, the PWA improved the concentrations of blood calcium and phosphorous in pigs fed MLP diets. Funding: Agrivida and Animal Health and Production and Animal Products: Improved Nutritional Performance, Growth, and Lactation of Animals from the USDA-NIFA.

Effect of low-protein diet and its duration on hair composition

1977 ◽  
Vol 16 (4) ◽  
pp. 241-247 ◽  
Author(s):  
O. M. Metwalli ◽  
S. I. Salem ◽  
S. L. Abdel-Razik
Keyword(s):  
Protein Diet ◽  
Low Protein Diet ◽  
Low Protein

scholarly journals Typical gut indigenous bacteria in ICR mice fed a soy protein-based normal or low-protein diet

2021 ◽  
Vol 4 ◽  
pp. 295-300
Author(s):  
Saori Nakamura ◽  
Takashi Kuda ◽  
Yuko Midorikawa ◽  
Hajime Takahashi ◽  
Bon Kimura
Keyword(s):  
Soy Protein ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Indigenous Bacteria ◽  
Icr Mice ◽  
Low Protein
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