An ultrastructural and cytochemical study of microbodies in the genus Nitella (Characeae)

1973 ◽  
Vol 51 (11) ◽  
pp. 2025-2032 ◽  
Author(s):  
B. A. Silverberg ◽  
T. Sawa
Keyword(s):  
Enzyme Assay ◽  
The Body ◽  
Cytochemical Localization ◽  
Cytochemical Study ◽  
Spherical Inclusions ◽  
Complete Digestion ◽  
Assay Methods ◽  
Granular Matrix ◽  
Available Information

Electron microscopy of the cells of the characean alga Nitella flexilis revealed the presence of numerous spherical inclusions which morphologically resemble plant microbodies. The structures have a dense granular matrix and are bounded by a single membrane. Many of the microbodies contain very electron-dense nucleoids that were shown to be alpha-amylase sensitive. In cells of the young apex, microbodies are the most abundant cellular organelle and are intimately associated with dilated cisternae of the endoplasmic reticulum and Golgi complexes, and with large osmiophilic lipid bodies. Although the microbody population appears reduced in mature branchlet cells and internode cells of the main axis, they exhibit a characteristic and frequent association with the chloroplasts. Turnover of microbodies involves some autolytic degradation of the body matrix until complete digestion presumably occurs. Developmental changes of microbodies were monitored with the cytochemical localization of lysosomal aryl sulfatase and acid phosphatase activities. The current study is of interest since catalase, an enzyme marker of microbodies in a variety of tissues, could not be detected using both cytochemical and enzyme assay methods. The functional role of microbodies in Nitella cells is explored in relation to presently available information.

scholarly journals Vector of Spatial Development of the Yenisei Siberia Regions: Krasnoyarsk Territory, Republic of Khakassia, Republic of Tuva

2019 ◽  
Vol 26 (7) ◽  
pp. 41-54
Author(s):  
S. M. Okladnikov ◽  
S. I. Berezovskaya ◽  
A. G. Mineev
Keyword(s):  
Open Data ◽  
New Economy ◽  
The Body ◽  
Resource Potential ◽  
Investment Projects ◽  
Regional Product ◽  
Available Information ◽  
Goals And Objectives ◽  
Qualitative Characteristics

This article provides a comprehensive assessment of the natural resource potential of the Krasnoyarsk Territory, the Republics of Khakassia and Tuva as part of implementing the «Yenisei Siberia» project. In the introductory section of the article, the authors set out the goals and objectives of the study of the quantitative and qualitative characteristics of the socio-economic potential of the Krasnoyarsk Territory, Republic of Khakassia, Republic of Tuva and examine the role of implementing particularly important Yenisei Siberia investment projects in the economic development of the territories. The body of the article starts with the overall review in the form of economic and statistical analysis of the socio-economic conditions in the regions examined. It is followed by an attempt at a statistical measurement of the influence of particularly important investment projects («Southern Cluster», «Construction of the railway Elegest - Kyzyl - Kuragino», «Construction of the timber processing complex in the Boguchansky district of the Krasnoyarsk Territory» and «Agro-industrial Park «Siberia») on a summarizing indicator of the economic activity of the regions - gross regional product (GRP). The investment projects were examined using open data sources and official statistical information. By comparing the available information from various sources, the authors assessed the adequacy of the obtained results to the current situation and challenges of the new economy.

scholarly journals Sirtuins as Important Factors in Pathological States and the Role of Their Molecular Activity Modulators

2021 ◽  
Vol 22 (2) ◽  
pp. 630
Author(s):  
Ewa Maria Kratz ◽  
Katarzyna Sołkiewicz ◽  
Adriana Kubis-Kubiak ◽  
Agnieszka Piwowar
Keyword(s):  
Oxidative Stress ◽  
Histone Deacetylases ◽  
Wide Spectrum ◽  
Cellular Level ◽  
The Body ◽  
Human Organism ◽  
Biochemical Processes ◽  
Pathological Conditions ◽  
Available Information

Sirtuins (SIRTs), enzymes from the family of NAD+-dependent histone deacetylases, play an important role in the functioning of the body at the cellular level and participate in many biochemical processes. The multi-directionality of SIRTs encourages scientists to undertake research aimed at understanding the mechanisms of their action and the influence that SIRTs have on the organism. At the same time, new substances are constantly being sought that can modulate the action of SIRTs. Extensive research on the expression of SIRTs in various pathological conditions suggests that regulation of their activity may have positive results in supporting the treatment of certain metabolic, neurodegenerative or cancer diseases or this connected with oxidative stress. Due to such a wide spectrum of activity, SIRTs may also be a prognostic markers of selected pathological conditions and prove helpful in assessing their progression, especially by modulating their activity. The article presents and discusses the activating or inhibiting impact of individual SIRTs modulators. The review also gathered selected currently available information on the expression of SIRTs in individual disease cases as well as the biological role that SIRTs play in the human organism, also in connection with oxidative stress condition, taking into account the progress of knowledge about SIRTs over the years, with particular reference to the latest research results.

scholarly journals CONSEQUENCE OF PATHYA-APATHYA AND LIFE STYLE IN THE DISORDERS OF URDHVAJATRU (SUPRACLAVICULAR) REGION-A REVIEW

AYUSHDHARA ◽  
2020 ◽  
pp. 2757-2763
Author(s):  
Divyarani Kathad ◽  
Hemangi Shukla ◽  
Jitendra Varsakiya
Keyword(s):  
Life Style ◽  
Good Health ◽  
The Body ◽  
Dietary Advice ◽  
The Sun ◽  
Sense Organs ◽  
Dietary Regimen ◽  
Effect Of Treatment ◽  
Available Information

Our ancient seers have given importance to Shirah (head) as it is part of the body where life along with sense faculties resides. All the sense organs and the channels carrying the sensory and vital impulses from the Shir (head) are like the rays of the sun. It is necessary to care for Urdhvajatru. In Ayurveda classics mentioned the concept of Pathya (wholesome) and Apathaya (unwholesome) as a part of the treatment of the diseases also a part of regime of healthy living. A person needs to follow a healthy diet and regimen so as to prevent any anomalies in life or to maintain good health. Shalakya Tantra has mentioned proper diet to take in particular disease which is necessary to enhance the effect of treatment and prevent the disease and also useful procedures which are part of Dinacharya to maintain routine health. The aim is to evaluate the role of Pathya- Apathya and dietary regimen mentioned in Shalakya Tantra to prevent the supraclavicular disease. Relevant Ayurveda and modern literature, available information on internet etc, were searched. The dietary advice and various Dinacharya modalities gives nourishment to the supra clavicular region and cures ailments of related and also provides preventive and curative benefits.

The effects of feeding level during both pregnancy and lactation on long-term productivity and body composition of sows

1991 ◽  
Vol 1991 ◽  
pp. 9-9
Author(s):  
P.A. Lee ◽  
W.H. Close
Keyword(s):  
Body Composition ◽  
Late Pregnancy ◽  
The Body ◽  
Feeding Level ◽  
Body Reserves ◽  
Pregnancy And Lactation ◽  
Inadequate Nutrition ◽  
Available Information

Body reserves play an important role in reproduction because they can be used by the sow to buffer against inadequate nutrition when metabolic demands are high, especially in late pregnancy and lactation. There is, however, little available information on the dynamic role of body reserves during reproduction and the present experiments were designed to demonstrate how the body reserves of the sow change in response to different nutritional inputs and to determine whether these influence sow productivity.

Mitochondrial matrix calcium ions regulate energy production in myocardium: A cytochemical study

1990 ◽  
Vol 48 (2) ◽  
pp. 166-167
Author(s):  
W.A. Jacob ◽  
R. Hertsens ◽  
A. Van Bogaert ◽  
M. De Smet
Keyword(s):  
Energy Metabolism ◽  
Calcium Ions ◽  
Energy Production ◽  
Regulation Of Respiration ◽  
Free Calcium ◽  
Mitochondrial Matrix ◽  
Cytochemical Study ◽  
Nmr Techniques

In the past most studies of the control of energy metabolism focus on the role of the phosphorylation potential ATP/ADP.Pi on the regulation of respiration. Studies using NMR techniques have demonstrated that the concentrations of these compounds for oxidation phosphorylation do not change appreciably throughout the cardiac cycle and during increases in cardiac work. Hence regulation of energy production by calcium ions, present in the mitochondrial matrix, has been the object of a number of recent studies.Three exclusively intramitochondnal dehydrogenases are key enzymes for the regulation of oxidative metabolism. They are activated by calcium ions in the low micromolar range. Since, however, earlier estimates of the intramitochondnal calcium, based on equilibrium thermodynamic considerations, were in the millimolar range, a physiological correlation was not evident. The introduction of calcium-sensitive probes fura-2 and indo-1 made monitoring of free calcium during changing energy metabolism possible. These studies were performed on isolated mitochondria and extrapolation to the in vivo situation is more or less speculative.

The Role of Polyphenols in the Modulation of Plasma Non-Enzymatic Antioxidant Capacity (NEAC)

2012 ◽  
Vol 82 (3) ◽  
pp. 228-232 ◽  
Author(s):  
Mauro Serafini ◽  
Giuseppa Morabito
Keyword(s):  
Antioxidant Capacity ◽  
Dietary Intervention ◽  
Ex Vivo ◽  
The Body ◽  
Dietary Polyphenols ◽  
Enzymatic Antioxidant ◽  
Endogenous Antioxidant

Dietary polyphenols have been shown to scavenge free radicals, modulating cellular redox transcription factors in different in vitro and ex vivo models. Dietary intervention studies have shown that consumption of plant foods modulates plasma Non-Enzymatic Antioxidant Capacity (NEAC), a biomarker of the endogenous antioxidant network, in human subjects. However, the identification of the molecules responsible for this effect are yet to be obtained and evidences of an antioxidant in vivo action of polyphenols are conflicting. There is a clear discrepancy between polyphenols (PP) concentration in body fluids and the extent of increase of plasma NEAC. The low degree of absorption and the extensive metabolism of PP within the body have raised questions about their contribution to the endogenous antioxidant network. This work will discuss the role of polyphenols from galenic preparation, food extracts, and selected dietary sources as modulators of plasma NEAC in humans.

The Role of Computer Modeling in Electrocardiography

1990 ◽  
Vol 29 (04) ◽  
pp. 282-288 ◽  
Author(s):  
A. van Oosterom
Keyword(s):  
Electrical Activity ◽  
Computer Modeling ◽  
Body Surface ◽  
Electrical Current ◽  
The Body ◽  
Volume Conductor ◽  
Current Generator ◽  
Cardiac Electrical Activity ◽  
Source Models

AbstractThis paper introduces some levels at which the computer has been incorporated in the research into the basis of electrocardiography. The emphasis lies on the modeling of the heart as an electrical current generator and of the properties of the body as a volume conductor, both playing a major role in the shaping of the electrocardiographic waveforms recorded at the body surface. It is claimed that the Forward-Problem of electrocardiography is no longer a problem. Several source models of cardiac electrical activity are considered, one of which can be directly interpreted in terms of the underlying electrophysiology (the depolarization sequence of the ventricles). The importance of using tailored rather than textbook geometry in inverse procedures is stressed.

Questions on the role of biofilms for the adaptation of microorganisms to unfavorable environmental factors by the example of P. aeruginosa

2020 ◽  
Vol 99 (4) ◽  
pp. 379-383
Author(s):  
Vasily N. Afonyushkin ◽  
N. A. Donchenko ◽  
Ju. N. Kozlova ◽  
N. A. Davidova ◽  
V. Yu. Koptev ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Environmental Factors ◽  
Barrier Function ◽  
Infectious Agent ◽  
Antagonistic Activity ◽  
The Body ◽  
Main Function ◽  
Pathogenic Potential ◽  
The Face

Pseudomonas aeruginosa is a widely represented species of bacteria possessing of a pathogenic potential. This infectious agent is causing wound infections, fibrotic cystitis, fibrosing pneumonia, bacterial sepsis, etc. The microorganism is highly resistant to antiseptics, disinfectants, immune system responses of the body. The responses of a quorum sense of this kind of bacteria ensure the inclusion of many pathogenicity factors. The analysis of the scientific literature made it possible to formulate four questions concerning the role of biofilms for the adaptation of P. aeruginosa to adverse environmental factors: Is another person appears to be predominantly of a source an etiological agent or the source of P. aeruginosa infection in the environment? Does the formation of biofilms influence on the antibiotic resistance? How the antagonistic activity of microorganisms is realized in biofilm form? What is the main function of biofilms in the functioning of bacteria? A hypothesis has been put forward the effect of biofilms on the increase of antibiotic resistance of bacteria and, in particular, P. aeruginosa to be secondary in charcter. It is more likely a biofilmboth to fulfill the function of storing nutrients and provide topical competition in the face of food scarcity. In connection with the incompatibility of the molecular radii of most antibiotics and pores in biofilm, biofilm is doubtful to be capable of performing a barrier function for protecting against antibiotics. However, with respect to antibodies and immunocompetent cells, the barrier function is beyond doubt. The biofilm is more likely to fulfill the function of storing nutrients and providing topical competition in conditions of scarcity of food resources.

Receptions of the Past: Commemoration, Racism, Desire

Somatechnics ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. 288-303
Author(s):  
Michael Connors Jackman
Keyword(s):  
Critical Point ◽  
Social Relations ◽  
White Privilege ◽  
Body Politic ◽  
The Body ◽  
Race And Racism ◽  
Lesbian And Gay ◽  
The Past ◽  
History Of

This article investigates the ways in which the work of The Body Politic (TBP), the first major lesbian and gay newspaper in Canada, comes to be commemorated in queer publics and how it figures in the memories of those who were involved in producing the paper. In revisiting a critical point in the history of TBP from 1985 when controversy erupted over race and racism within the editorial collective, this discussion considers the role of memory in the reproduction of whiteness and in the rupture of standard narratives about the past. As the controversy continues to haunt contemporary queer activism in Canada, the productive work of memory must be considered an essential aspect of how, when and for what reasons the work of TBP comes to be commemorated. By revisiting the events of 1985 and by sifting through interviews with individuals who contributed to the work of TBP, this article complicates the narrative of TBP as a bluntly racist endeavour whilst questioning the white privilege and racially-charged demands that undergird its commemoration. The work of producing and preserving queer history is a vital means of challenging the intentional and strategic erasure of queer existence, but those who engage in such efforts must remain attentive to the unequal terrain of social relations within which remembering forms its objects.

A Good Sentencing Precedent is Hard to Find

2020 ◽  
Vol 32 (3) ◽  
pp. 138-144
Author(s):  
Brian A. Jacobs
Keyword(s):  
United States ◽  
Significant Role ◽  
College Admissions ◽  
The Body ◽  
Federal Law ◽  
Criminal Cases ◽  
Federal Sentencing

In federal criminal cases, federal law requires that judges consider the sentences other courts have imposed in factually similar matters. Courts and parties, however, face significant challenges in finding applicable sentencing precedents because judges do not typically issue written sentencing opinions, and transcripts of sentencings are not readily available in advanced searchable databases. At the same time, particularly since the Supreme Court’s 2005 decision in United States v. Booker, sentencing precedent has come to play a significant role in federal sentencing proceedings. By way of example, this article discusses recent cases involving defendants with gambling addictions, and recent cases involving college admissions or testing fraud. The article explores the ways the parties in those cases have used sentencing precedent in their advocacy, as well as the ways the courts involved have used sentencing precedent to justify their decisions. Given the important role of sentencing precedent in federal criminal cases, the article finally looks at ways in which the body of sentencing law could be made more readily available to parties and courts alike.

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