PHOMIC ACID: A TOXIC METABOLITE FROM PHOMA MEDICAGINIS MALBR. AND ROUM.
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A crystalline toxic metabolite was isolated from culture filtrates of Phoma medicaginis, the fungus causing the black stem and leaf spot disease of alfalfa. Ion exchange methods employed for its isolation are presented. It inhibits the germination of flax and rape seed, melts at 259–260 °C, and has absorption peaks at 208 and 260 mμ. in water. It differs markedly from ascochytine isolated earlier from cultures of Ascochyta pisi and A. fabae. The name 'phomic acid' is suggested for the toxin.
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2016 ◽
Vol 63
(2)
◽
pp. 119-127
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