Bifurcation Analysis of an Elliptic Free Boundary Problem Modelling the Growth of Avascular Tumors

2007 ◽  
Vol 39 (1) ◽  
pp. 210-235 ◽  
Author(s):  
Shangbin Cui ◽  
Joachim Escher
2015 ◽  
Vol 26 (4) ◽  
pp. 401-425 ◽  
Author(s):  
FUJUN ZHOU ◽  
JUNDE WU

Of concern is the stability and bifurcation analysis of a free boundary problem modelling the growth of multi-layer tumours. A remarkable feature of this problem lies in that the free boundary is imposed with nonlinear boundary conditions, where a Gibbs–Thomson relation is taken into account. By employing a functional approach, analytic semigroup theory and bifurcation theory, we prove that there exists a positive threshold value γ* of surface tension coefficient γ such that if γ > γ* then the unique flat stationary solution is asymptotically stable under non-flat perturbations, while for γ < γ* this unique flat stationary solution is unstable and there exists a series of non-flat stationary solutions bifurcating from it. The result indicates a significant phenomenon that a smaller value of surface tension coefficient γ may make tumours more aggressive.


MAT Serie A ◽  
2001 ◽  
Vol 5 ◽  
pp. 37-41
Author(s):  
Claudia Lederman ◽  
Juan Luis Vázquez ◽  
Noemí Wolanski

2008 ◽  
Vol 05 (04) ◽  
pp. 785-806
Author(s):  
KAZUAKI NAKANE ◽  
TOMOKO SHINOHARA

A free boundary problem that arises from the physical phenomenon of "peeling a thin tape from a domain" is treated. In this phenomenon, the movement of the tape is governed by a hyperbolic equation and is affected by the peeling front. We are interested in the behavior of the peeling front, especially, the phenomenon of self-excitation vibration. In the present paper, a mathematical model of this phenomenon is proposed. The cause of this vibration is discussed in terms of adhesion.


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