scholarly journals Using cytology to identify skin diseases

2020 ◽  
Vol 187 (1) ◽  
pp. 39-39
Keyword(s):  
Skin Diseases ◽  
Clinical Pathology ◽  
Royal Veterinary College

Reviewed by Zoe Miller, a resident in clinical pathology at the Royal Veterinary College.

Confirmatory field study for the evaluation of ciclosporin at a target dose of 7.0 mg/kg (3.2 mg/lb) in the control of feline hypersensitivity dermatitis

2016 ◽  
Vol 18 (11) ◽  
pp. 889-897 ◽  
Author(s):  
Elizabeth S Roberts ◽  
Cindy Speranza ◽  
Cecilia Friberg ◽  
Craig Griffin ◽  
Jean Steffan ◽  
...  
Keyword(s):  
Adverse Events ◽  
Field Study ◽  
Skin Diseases ◽  
Clinical Pathology ◽  
Gastrointestinal Disorders ◽  
Placebo Control ◽  
Lesion Score ◽  
Target Dose ◽  
Daily Dose ◽  
Physical Examinations

Objectives This study was designed to confirm the efficacy and tolerability of a daily dose of 7.0 mg/kg (3.2 mg/lb) ciclosporin (CsA) in the treatment of feline hypersensitivity dermatitis (HD), as this includes some of the most frequently suspected skin diseases in cats and recent publications have reported the successful use of CsA in the treatment of feline HD. Methods In total, 217 cats with feline HD were treated daily for 42 days with a target dose of 7 mg/kg CsA (n = 144) or a placebo control (n = 73) administered either in the food or directly in the mouth following feeding. Clinical and dermatological evaluations were conducted on days 0, 21 and 42, or study exit. Safety was evaluated through physical examinations, clinical pathology and the monitoring of adverse events (AEs). Results Administration of CsA at 7.0 mg/kg produced a significant improvement in the total lesion score ( P <0.0001). The average reduction from visit 1 to visit 3 was 65.1% in the CsA group (9.2% for the placebo). In addition, owners assessed 78.3% of the cases in the CsA group as a success. Statistically significant recoveries were also seen in extent of lesions, investigator assessment of overall improvement, and mean improvement in both the investigators’ and owners’ assessment of pruritus. Mild gastrointestinal disorders were the most common AEs but did not require cessation of therapy. Conclusions and relevance Results confirm that 7.0 mg/kg CsA dosed daily in food or orally for up to 6 weeks is effective and well tolerated by cats with feline HD.

On Future Directions in Pathology

1982 ◽  
Vol 40 ◽  
pp. 274-277
Author(s):  
Benjamin F. Trump ◽  
Irene K. Berezesky ◽  
Raymond T. Jones
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Clinical Pathology ◽  
Future Directions ◽  
Diagnostic Pathology ◽  
The Past ◽  
Transmission Electron ◽  
Organ Systems ◽  
The Many

The role of electron microscopy and associated techniques is assured in diagnostic pathology. At the present time, most of the progress has been made on tissues examined by transmission electron microscopy (TEM) and correlated with light microscopy (LM) and by cytochemistry using both plastic and paraffin-embedded materials. As mentioned elsewhere in this symposium, this has revolutionized many fields of pathology including diagnostic, anatomic and clinical pathology. It began with the kidney; however, it has now been extended to most other organ systems and to tumor diagnosis in general. The results of the past few years tend to indicate the future directions and needs of this expanding field. Now, in addition to routine EM, pathologists have access to the many newly developed methods and instruments mentioned below which should aid considerably not only in diagnostic pathology but in investigative pathology as well.

Impact of skin diseases on military operations

1969 ◽  
Vol 100 (6) ◽  
pp. 702-702 ◽  
Author(s):  
M. B. Sulzberger
Keyword(s):  
Skin Diseases ◽  
Military Operations

The Constructive Thinking Inventory: Factorial Structure in Healthy Individuals and Patients with Chronic Skin Diseases

1998 ◽  
Vol 14 (3) ◽  
pp. 226-233 ◽  
Author(s):  
Jürgen Hoyer ◽  
Mechthild Averbeck ◽  
Thomas Heidenreich ◽  
Ulrich Stangier ◽  
Karin Pöhlmann ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Principal Component ◽  
Initial Study ◽  
Statistical Independence ◽  
Constructive Thinking ◽  
Global Factor ◽  
Emotional Coping ◽  
Factor Congruence ◽  
Chronic Skin ◽  
Chronic Skin Diseases

Epstein's “Constructive Thinking Inventory” (CTI) was developed to measure the construct of experiential intelligence, which is based on his cognitive-experiential self-theory. Inventory items were generated by sampling naturally occurring automatic cognitions. Using principal component analysis, the findings showed a global factor of coping ability as well as six main factors: Emotional Coping, Behavioral Coping, Categorical Thinking, Personal Superstitious Thinking, Esoteric Thinking, and Naive Optimism. We tested the replicability of this factor structure and the amount of statistical independence (nonredundancy) between these factors in an initial study of German students (Study 1, N = 439) and in a second study of patients with chronic skin disorders (Study 2, N = 187). Factor congruence with the original (American) data was determined using a formula proposed by Schneewind and Cattell (1970) . Our findings show satisfactory factor congruence and statistical independence for Emotional Coping and Esoteric Thinking in both studies, while full replicability or independence could not be found in both for the other factors. Implications for the use and further development of the CTI are discussed.

Investigating Personality and Psychopathology in Patients With Psoriasis

2017 ◽  
Vol 38 (2) ◽  
pp. 87-107 ◽  
Author(s):  
Chiara Vari ◽  
Patrizia Velotti ◽  
Alessandro Crisi ◽  
Silvana Carlesimo ◽  
Antonio G. Richetta ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Clinical Importance ◽  
Self Report ◽  
Psychological Issues ◽  
Self Evaluation ◽  
Affective Quality ◽  
Millon Clinical Multiaxial Inventory ◽  
Study Results ◽  
Completion Test ◽  
Skin Conditions

Abstract. A broad range of literature reported higher rates of psychopathology and personality disorders among patients affected by skin conditions. Specifically, depression, anxiety, and suicidal ideations are more frequently reported by patients affected by skin diseases. This study aimed to examine psychopathology and personality in a group of patients affected by psoriasis by means of a self-report measure (Millon Clinical Multiaxial Inventory – MCMI-III) and a performance-based technique (Wartegg Drawing Completion Test [WDCT], CWS). Study results showed a higher rate of passive-aggressiveness and paranoia among psoriatic patients (MCMI-III). When assessing patients through the performance-based technique (WDCT, CWS), a higher rate of global rejection (GR) – linked by previous literature to suicidal ideation – and a lower affective quality of the drawings emerged. We discuss the clinical importance of detecting psychological issues in dermatology patients by means of a multimethod assessment that goes beyond patients’ self-evaluation of their symptoms and emotions.

The Adaptation of Medical Records to Epidemiological Use

1965 ◽  
Vol 04 (03) ◽  
pp. 136-140
Author(s):  
Cl Jeanty
Keyword(s):  
Medical Records ◽  
Clinical Pathology ◽  
Time Variable ◽  
Special Care ◽  
General Description ◽  
Causal Relations ◽  
Laboratory Techniques ◽  
Original Record ◽  
Statistical Studies

A method is described in an attempt to make medical records suitable for epidemiologigri: purposes. Every case of a disease is recorded on an appropriate punched card with the object of working towards a general description of a disease through the collation of several cases of the same diagnosis. This punched card represents a very great condensation of the original record. Special care has been applied to state as precisely as possible the time variable, particularly as far as its origin and unit of measure are concerned, in order to demonstrate the existence of causal relations between diseases. Such cards are also intended to make easier statistical studies in clinical pathology, in evaluation of new laboratory techniques, and in therapeutical trials.

Sign in / Sign up

Export Citation Format

Share Document