TB control strategy

2015 ◽  
Vol 176 (21) ◽  
pp. 551-552
Author(s):  
N. Blake ◽  
A. Cobner ◽  
J. Wilson ◽  
A. Davis
Keyword(s):  
2013 ◽  
Vol 173 (19) ◽  
pp. 481.1-481
Author(s):  
Declan O'Rourke ◽  
Neil Blake
Keyword(s):  

2015 ◽  
Vol 176 (23) ◽  
pp. 601-601 ◽  
Author(s):  
J. Blackwell
Keyword(s):  

2008 ◽  
Vol 16 (1) ◽  
pp. 49-54 ◽  
Author(s):  
Guomiao Shen ◽  
Digambar Behera ◽  
Manpreet Bhalla ◽  
Arthur Nadas ◽  
Suman Laal

ABSTRACT Tuberculosis (TB) is a major cause of morbidity and mortality, especially in developing countries. Despite significant limitations, microscopy remains the cornerstone of the global TB control strategy. As the TB epidemic escalates, new diagnostic methods that are accurate and also economical and simple to manufacture and deploy are urgently needed. Although several promising antigens have been identified and evaluated in recent years, the reproducible production of high-quality recombinant mycobacterial proteins with minimal batch-to-batch variation is difficult, laborious, and expensive. To determine the feasibility of devising a synthetic peptide-based diagnostic test for TB, we have delineated the immunodominant epitopes of three candidate antigens, Ag85B, BfrB, and TrxC, that were previously identified to be immunogenic in TB patients. The results demonstrate that combinations of carefully selected synthetic peptides derived from highly immunogenic proteins can be the basis for devising an immunodiagnostic test for TB.


2013 ◽  
Vol 142 (10) ◽  
pp. 2036-2048 ◽  
Author(s):  
T. LUO ◽  
A. SUMI ◽  
D. ZHOU ◽  
N. KOBAYASHI ◽  
K. MISE ◽  
...  

SUMMARYWe investigated the seasonality of tuberculosis (TB) in Wuhan, China, to evaluate the increased risk of disease transmission during each season and to develop an effective TB control strategy. We applied spectral analysis to the weekly prevalence data of sputum smear positive (SSP) and sputum smear negative (SSN) pulmonary TB reported from 2006 to 2010. Cases of both SSP and SSN feature 1·0- and 0·5-year periodic modes. The least squares method was used to fit curves to the two periodic modes for SSP and SSN data. The curves demonstrated dominant peaks in spring similar to cases reported previously for other locations. Notably for SSP, dominant peaks were also observed in summer. The spring peaks of SSP and SSN were explained in terms of poorly ventilated and humid rooms and vitamin D deficiency. For the summer peaks of SSP, summer influenza epidemics in Wuhan may contribute to the increase in TB prevalence.


2017 ◽  
Vol 24 (07) ◽  
pp. 1044-1048
Author(s):  
Alia Liaqat ◽  
Muhammad Awais Iqbal ◽  
Muhammad Abdur Rehman Khadam

Background: TB is highly prevalent in Pakistan. The Pakistan government has,therefore, given high priority to Tuberculosis control. It has declared TB to be considered asNational Emergency in 2001, and has extended the WHO suggested TB control strategy (orDOTS) throughout the all health services of the Health Ministry by May of 20051.Therefore it isvery essential to assess the knowledge about TB and its implementation in tertiary hospitalswhich are the main source of providing treatment. Objectives: To assess the knowledge ofmedical offices about the diagnosis of tuberculosis case, treatment of tuberculosis casesand the practice of TB DOTS by the MOs in teaching hospitals of Faisalabad City. Place andDuration of Study: It was carried out in teaching hospitals. “Allied Hospital and district headquarter hospital” in Faisalabad City, in one month from 10 June 2014 to July 10 2014, Fifty MOswere assessed by the questionnaires methodology. Study Design: The study design was crosssectional study. Sample Technique: Simple non-random sampling. Materials & Methods: TheMOs were given the questionnaires and before filling it, they were also provided with consentform, to get their consent in written. The sample of consent form and questionnaires aregiven at end. MOs are assessed randomly. Results: In this study, the response obtained inquestionnaires were analyzed individually. When we calculate the percentage of doctors haveknowledge about DOTS in Faisalabad. We get following results: 77.5% of MOS in teachinghospital of Faisalabad have knowledge about DOTS in Faisalabad. When we calculate thepercentage of doctors practicing DOTS in Faisalabad. We get following results so 18.64% ofMOs practice DOTS. Conclusion: It was concluded from this study that though majority of MOshave the knowledge but they are not practicing it. So there is a need of strict enforcement toimplement this program effectively to achieve a better control of TB under guidelines of WHO.


1980 ◽  
Author(s):  
Harold F. Engler ◽  
Esther L. Davenport ◽  
Joanne Green ◽  
William E. Sears

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