Cerebellar cortical degeneration in Hungarian vizslas

2014 ◽  
Vol 174 (13) ◽  
pp. 334.1-334
Author(s):  
Joe Fenn ◽  
Patrick J. Kenny
Keyword(s):  
Cerebellar Cortical Degeneration

Late onset cerebellar cortical degeneration in a koala

2009 ◽  
Vol 87 (8) ◽  
pp. 342-344 ◽  
Author(s):  
M Kuwamura ◽  
F Murai ◽  
S Nishioka ◽  
M Aoki ◽  
F Ohashi ◽  
...  
Keyword(s):  
Late Onset ◽  
Cerebellar Cortical Degeneration

scholarly journals Cerebellar cortical degeneration with ovarian carcinoma.

1982 ◽  
Vol 58 (675) ◽  
pp. 47-51 ◽  
Author(s):  
M. M. Steven ◽  
I. R. Mackay ◽  
P. R. Carnegie ◽  
P. S. Bhathal ◽  
R. M. Anderson
Keyword(s):  
Ovarian Carcinoma ◽  
Cerebellar Cortical Degeneration

Ataxia telangiectasia: a “disease model” to understand the cerebellar control of vestibular reflexes

2011 ◽  
Vol 105 (6) ◽  
pp. 3034-3041 ◽  
Author(s):  
Aasef G. Shaikh ◽  
Sarah Marti ◽  
Alexander A. Tarnutzer ◽  
Antonella Palla ◽  
Thomas O. Crawford ◽  
...  
Keyword(s):  
Ataxia Telangiectasia ◽  
Disease Model ◽  
Head Rotation ◽  
Vestibular Evoked Myogenic Potentials ◽  
Electromyographic Activity ◽  
Vestibular Reflexes ◽  
Healthy Humans ◽  
Motor Strategy ◽  
Eye Rotation ◽  
Cerebellar Cortical Degeneration

Experimental animal models have suggested that the modulation of the amplitude and direction of vestibular reflexes are important functions of the vestibulocerebellum and contribute to the control of gaze and balance. These critical vestibular functions have been infrequently quantified in human cerebellar disease. In 13 subjects with ataxia telangiectasia (A-T), a disease associated with profound cerebellar cortical degeneration, we found abnormalities of several key vestibular reflexes. The vestibuloocular reflex (VOR) was measured by eye movement responses to changes in head rotation. The vestibulocollic reflex (VCR) was assessed with cervical vestibular-evoked myogenic potentials (cVEMPs), in which auditory clicks led to electromyographic activity of the sternocleidomastoid muscle. The VOR gain (eye velocity/head velocity) was increased in all subjects with A-T. An increase of the VCR, paralleling that of the VOR, was indirectly suggested by an increase in cVEMP amplitude. In A-T subjects, alignment of the axis of eye rotation was not with that of head rotation. Subjects with A-T thus manifested VOR cross-coupling, abnormal eye movements directed along axes orthogonal to that of head rotation. Degeneration of the Purkinje neurons in the vestibulocerebellum probably underlie these deficits. This study offers insights into how the vestibulocerebellum functions in healthy humans. It may also be of value to the design of treatment trials as a surrogate biomarker of cerebellar function that does not require controlling for motivation or occult changes in motor strategy on the part of experimental subjects.

scholarly journals Conditioning and aversion to toxic Solanum bonariense ("naranjillo") leaves in calves

2015 ◽  
Vol 46 (4) ◽  
pp. 669-673
Author(s):  
Paul Ruiz-Santos ◽  
James Alan Pfister ◽  
José Manuel Verdes
Keyword(s):  
Plant Material ◽  
Treated Group ◽  
Conditioned Aversion ◽  
Control Group ◽  
Oral Gavage ◽  
Conditioning Period ◽  
Ad Libitum ◽  
Entire Amount ◽  
Cerebellar Cortical Degeneration ◽  
Target Plant

ABSTRACT: Solanum bonariense is a perennial poisonous shrub that induces cerebellar cortical degeneration when eaten by cattle. The aim of this research was to outline a protocol to induce a conditioned aversion to this plant. During the pre-conditioning period ten calves (126±12kg BW) were maintained at half of their normal energy intake with lucerne hay and water ad libitum, to stimulate consumption of S. bonariense. Every two days they were offered 100g ofS. bonariense leaves for 5 minutes. Calves began eating the target plant on day 10 and consumed all the plant material on day 12. The conditioning period began after each calf consumed the entire amount of S. bonariense for three consecutive sessions. Five animals were randomly selected for conditioning, and after ingestion ofS. bonariense they were dosed by oral gavage with lithium chloride (LiCl) at 200mg kg-1 BW (treated group), while the other five received a similar volume of water by oral gavage (control group). After 2 doses of LiCl the treated group ate no S. bonariense while the control group consumed the entire 100g. We confirmed that LiCl is a powerful tool to induce conditioned aversions against S. bonariense in calves, which persists for at least 3 months.

CEREBELLAR CORTICAL DEGENERATION DUE TO ACUTE AZIDE POISONING

Brain ◽  
1972 ◽  
Vol 95 (3) ◽  
pp. 505-516 ◽  
Author(s):  
FRED A. METTLER ◽  
DANIEL S. SAX
Keyword(s):  
Cerebellar Cortical Degeneration

CEREBELLAR CORTICAL DEGENERATION IN ASSOCIATION WITH SMALL–CELL CARCINOMA OF THE OESOPHAGUS

1989 ◽  
Vol 15 (2) ◽  
pp. 175-183 ◽  
Author(s):  
P. M. COX ◽  
M. H. VAZIR ◽  
R. K. H. PETTY ◽  
S. LAW ◽  
A. P. DHILLON
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Cerebellar Cortical Degeneration

Correlation of cerebellar volume with eyeblink conditioning in healthy subjects and in patients with cerebellar cortical degeneration

2008 ◽  
Vol 1198 ◽  
pp. 73-84 ◽  
Author(s):  
Albena Dimitrova ◽  
Marcus Gerwig ◽  
Beate Brol ◽  
Elke R. Gizewski ◽  
Michael Forsting ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Eyeblink Conditioning ◽  
Cerebellar Volume ◽  
Cerebellar Cortical Degeneration

scholarly journals Cerebellar Cortical Degeneration in a Japanese Black Bull

2013 ◽  
Vol 66 (8) ◽  
pp. 545-548
Author(s):  
Michihito TAGAWA ◽  
Shiori CHIBA ◽  
Hiroyuki OKAMATSU ◽  
Yuka KOJIMA ◽  
Kotaro MATSUMOTO ◽  
...  
Keyword(s):  
Cerebellar Cortical Degeneration
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