Fatal elephant endotheliotropic herpesvirus type 5 infection in a captive Asian elephant

2012 ◽  
Vol 171 (15) ◽  
pp. 380-381 ◽  
Author(s):  
Daniela Denk ◽  
Mark F. Stidworthy ◽  
Sharon Redrobe ◽  
Erin Latimer ◽  
Gary S. Hayward ◽  
...  
Keyword(s):  
Asian Elephant ◽  
Herpesvirus Type

scholarly journals Latency and Persistence of Bovine Herpesvirus Type 4, Strain B11-41, in Bovine Nervous Tissues

2003 ◽  
Vol 65 (1) ◽  
pp. 87-93 ◽  
Author(s):  
Akihiro ASANO ◽  
Yasuo INOSHIMA ◽  
Kenji MURAKAMI ◽  
Yuko IKETANI ◽  
Yasunori YAMAMOTO ◽  
...  
Keyword(s):  
Bovine Herpesvirus ◽  
Herpesvirus Type

scholarly journals Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair

2021 ◽  
Author(s):  
Laura A Murray-Nerger ◽  
Joshua L Justice ◽  
Pranav Rekapalli ◽  
Josiah E Hutton ◽  
Ileana M Cristea
Keyword(s):  
Cell Cycle ◽  
Dna Repair ◽  
Posttranslational Modifications ◽  
Cell Cycle Progression ◽  
Nuclear Periphery ◽  
Virus Production ◽  
Nuclear Lamina ◽  
Regulatory Function ◽  
Herpesvirus Type ◽  
Lamin B1

Abstract The integrity and regulation of the nuclear lamina is essential for nuclear organization and chromatin stability, with its dysregulation being linked to laminopathy diseases and cancer. Although numerous posttranslational modifications have been identified on lamins, few have been ascribed a regulatory function. Here, we establish that lamin B1 (LMNB1) acetylation at K134 is a molecular toggle that controls nuclear periphery stability, cell cycle progression, and DNA repair. LMNB1 acetylation prevents lamina disruption during herpesvirus type 1 (HSV-1) infection, thereby inhibiting virus production. We also demonstrate the broad impact of this site on laminar processes in uninfected cells. LMNB1 acetylation negatively regulates canonical nonhomologous end joining by impairing the recruitment of 53BP1 to damaged DNA. This defect causes a delay in DNA damage resolution and a persistent activation of the G1/S checkpoint. Altogether, we reveal LMNB1 acetylation as a mechanism for controlling DNA repair pathway choice and stabilizing the nuclear periphery.

SEROEPIDEMIOLOGIC STUDIES OF HERPESVIRUS TYPE 2 AND CARCINOMA OF THE CERVIX. IV. DYSPLASIA AND CARCINOMA IN SITU1

1973 ◽  
Vol 98 (2) ◽  
pp. 77-87 ◽  
Author(s):  
ERVIN ADAM ◽  
RAYMOND H. KAUFMAN ◽  
JOSEPH L. MELNICK ◽  
ALLAN H. LEVY ◽  
WILLIAM E. RAWLS
Keyword(s):  
Herpesvirus Type ◽  
Seroepidemiologic Studies

scholarly journals Social structure and demography of a remnant Asian elephant Elephas maximus population and the implications for survival

Oryx ◽  
2020 ◽  
pp. 1-6
Author(s):  
Lauren J. Hale ◽  
Kun Shi ◽  
Tania C. Gilbert ◽  
Kelvin S.-H. Peh ◽  
Philip Riordan
Keyword(s):  
Social Structure ◽  
Population Size ◽  
Total Population ◽  
Camera Traps ◽  
Asian Elephant ◽  
Elephas Maximus ◽  
Effective Density ◽  
Anthropogenic Pressures ◽  
Sex Ratio Bias ◽  
Elephant Population

Abstract The Asian elephant Elephas maximus is at risk of extinction as a result of anthropogenic pressures, and remaining populations are often small and fragmented remnants, occupying a fraction of the species' former range. Once widely distributed across China, only a maximum of 245 elephants are estimated to survive across seven small populations. We assessed the Asian elephant population in Nangunhe National Nature Reserve in Lincang Prefecture, China, using camera traps during May–July 2017, to estimate the population size and structure of this genetically important population. Although detection probability was low (0.31), we estimated a total population size of c. 20 individuals, and an effective density of 0.39 elephants per km2. Social structure indicated a strong sex ratio bias towards females, with only one adult male detected within the population. Most of the elephants associated as one herd but three adult females remained separate from the herd throughout the trapping period. These results highlight the fragility of remnant elephant populations such as Nangunhe and we suggest options such as a managed metapopulation approach for their continued survival in China and more widely.

scholarly journals Experimental Infection of Two Dogs with a Canine Isolate of Feline Herpesvirus Type 1

1991 ◽  
Vol 28 (4) ◽  
pp. 338-340 ◽  
Author(s):  
J. W. Kramer ◽  
J. F. Evermann ◽  
C. W. Leathers ◽  
A. J. McKeirnan ◽  
L. Rashti
Keyword(s):  
Experimental Infection ◽  
Herpesvirus Type ◽  
Feline Herpesvirus ◽  
Feline Herpesvirus Type 1
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