Myocardial cell damage in 24 dogs bitten by the common European viper (Vipera berus)

2010 ◽  
Vol 166 (22) ◽  
pp. 687-690 ◽  
Author(s):  
L. Pelander ◽  
I. Ljungvall ◽  
J. Haggstrom
Keyword(s):  
Cell Damage ◽  
Myocardial Cell ◽  
Vipera Berus ◽  
The Common ◽  
Myocardial Cell Damage

Evaluation of Myocardial Cell Damage by In-111-Monoclonal Antimyosin Antibodies in Patients Under Chronic Tricyclic Antidepressant Drug Treatment

Circulation ◽  
1995 ◽  
Vol 91 (6) ◽  
pp. 1619-1623 ◽  
Author(s):  
Vicens Martí ◽  
Manel Ballester ◽  
Claudi Udina ◽  
Ignasi Carrió ◽  
Enric Alvarez ◽  
...  
Keyword(s):  
Drug Treatment ◽  
Cell Damage ◽  
Antidepressant Drug ◽  
Myocardial Cell ◽  
Tricyclic Antidepressant ◽  
Antidepressant Drug Treatment ◽  
Myocardial Cell Damage

Myocyte cell damage after administration of doxorubicin or mitoxantrone in breast cancer patients assessed by indium 111 antimyosin monoclonal antibody studies.

1993 ◽  
Vol 11 (7) ◽  
pp. 1264-1268 ◽  
Author(s):  
M Estorch ◽  
I Carrió ◽  
D Martínez-Duncker ◽  
L Berná ◽  
G Torres ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Advanced Breast Cancer ◽  
Cell Damage ◽  
Myocardial Cell ◽  
Left Ventricular ◽  
Advanced Breast ◽  
Left Ventricular Ejection ◽  
Antimyosin Antibody ◽  
Indium 111 ◽  
Myocardial Cell Damage

PURPOSE To compare myocyte cell damage induced by doxorubicin or mitoxantrone, we performed left ventricular ejection fraction (LVEF) measurements and indium 111 antimyosin antibody studies in a group of patients with advanced breast cancer who had been treated with these anthracycline derivatives. PATIENTS AND METHODS We studied 35 patients eligible to receive chemotherapy including the anthracyclines: doxorubicin or mitoxantrone (cumulative dose of doxorubicin, 500 mg/m2; or mitoxantrone, 120 mg/m2). LVEF was measured before and after 10 cycles of chemotherapy. Antimyosin uptake in the myocardium was quantified by means of a heart-to-lung ratio (HLR). RESULTS Patients treated with doxorubicin presented with a significant decrease in LVEF after chemotherapy (before, 60.4% +/- 8.92%; after, 49.8% +/- 9.71%; P = .001). Antimyosin uptake was observed in all patients with a HLR of 2.03 +/- 0.25. Seven of eight patients with a HLR greater than 2.03 had a greater than 10% decrease in LVEF. Patients treated with mitoxantrone did not present with a decrease in LVEF after chemotherapy (before, 55.4% +/- 6.25%; after, 55.8% +/- 7.25%; not significant). Antimyosin uptake was observed in 14 of 17 patients with a HLR of 1.77 +/- 0.18 (P < .05). CONCLUSION 111In antimyosin monoclonal antibodies defect myocardial cell damage produced by doxorubicin and mitoxantrone. In patients with advanced breast cancer, cumulative doses of 120 mg/m2 of mitoxantrone produce less myocardial cell damage than cumulative doses of 500 mg/m2 of doxorubicin. 111In antimyosin uptake without decrease in LVEF after treatment with mitoxantrone indicates the presence of myocyte cell damage, but not to the extent necessary to deteriorate function. These results indicate that 111In antimyosin antibody studies are useful in the noninvasive comparative assessment of cardiotoxicity produced by different anthracycline derivatives.

scholarly journals Rapid, Highly Sensitive Immunoassay for Determination of Cardiac Troponin I in Patients with Myocardial Cell Damage

1997 ◽  
Vol 43 (8) ◽  
pp. 1464-1465 ◽  
Author(s):  
Mauro Panteghini ◽  
Roberto Bonora ◽  
Franca Pagani ◽  
Francesca Buffoli ◽  
Claudio Cuccia
Keyword(s):  
Cardiac Troponin ◽  
Troponin I ◽  
Cell Damage ◽  
Myocardial Cell ◽  
Cardiac Troponin I ◽  
Highly Sensitive ◽  
Myocardial Cell Damage

scholarly journals Evaluation of myocardial cell damage in cardiac lymph during cardiopulmonary bypass

Critical Care ◽  
10.1186/cc336 ◽  
1999 ◽  
Vol 3 (S2) ◽  
Author(s):  
JF Vazquez-Jimenez ◽  
Ma Qing ◽  
OJ Liakopoulos ◽  
RG Grabitz ◽  
G von Bernuth ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Cell Damage ◽  
Myocardial Cell ◽  
Myocardial Cell Damage

scholarly journals Localization and expression of heat shock protein 70 with rat myocardial cell damage induced by heat stress in vitro and in vivo

2014 ◽  
Vol 11 (3) ◽  
pp. 2276-2284 ◽  
Author(s):  
HONGBO CHEN ◽  
ABDELNASIR ADAM ◽  
YANFEN CHENG ◽  
SHU TANG ◽  
JÖRG HARTUNG ◽  
...  
Keyword(s):  
Heat Stress ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Heat Shock Protein 70 ◽  
Cell Damage ◽  
Myocardial Cell ◽  
Myocardial Cell Damage
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