scholarly journals Effect of peritoneal lavage solution temperature on body temperature in anaesthetised cats and small dogs

2017 ◽  
Vol 180 (20) ◽  
pp. 498-498 ◽  
Author(s):  
D. C. Barnes ◽  
E. A. Leece ◽  
T. A Trimble ◽  
J. L. Demetriou
Keyword(s):  
Body Temperature ◽  
Peritoneal Lavage ◽  
Solution Temperature ◽  
Lavage Solution

Lavage Solution Temperature Influences Depth of Chondrocyte Death and Surface Contouring during Thermal Chondroplasty with Temperature-Controlled Monopolar Radiofrequency Energy

2002 ◽  
Vol 30 (5) ◽  
pp. 667-673 ◽  
Author(s):  
Yan Lu ◽  
Ryland B. Edwards ◽  
Shane Nho ◽  
Brian J. Cole ◽  
Mark D. Markel
Keyword(s):  
Treatment Time ◽  
Solution Temperature ◽  
Confocal Laser ◽  
Radiofrequency Energy ◽  
Cartilage Surface ◽  
Chondrocyte Viability ◽  
Chondrocyte Death ◽  
Articular Cartilage Surface ◽  
Thermal Chondroplasty ◽  
Lavage Solution

Background: Although radiofrequency energy can smooth and contour cartilage surface, it has deleterious effects on chondrocyte viability. Hypothesis: Monopolar thermal chondroplasty in a 37°C lavage solution, as compared with a 22° lavage solution, will reduce chondrocyte death and result in greater smoothing of the articular cartilage surface. Study Design: Controlled laboratory study. Methods: Sixteen chondromalacic samples from patients undergoing total knee arthroplasty were divided into two groups: 22°C and 37°C lavage solution. Each sample was divided into two equal parts and half of each group was treated for 10 seconds and the other half for 15 seconds. Results: Confocal laser microscopy demonstrated that the depth of chondrocyte death in the 37°C lavage solution group was significantly less (range, 200 to 340 μm) than that in the 22°C solution group for both 10- and 15-second treatment times. Scanning electron microscopy demonstrated that the cartilage surface in the 37°C lavage solution group was smoother than that in the 22°C solution group for the 10-second treatment time. Energy delivery power in the 37°C lavage solution group was significantly lower than in the 22°C solution group for both treatment times. Conclusions: Thermal chondroplasty with 37°C lavage solution resulted in less depth of chondrocyte death and produced smoother surfaces than with 22°C solution for 10 seconds of treatment. Clinical Relevance: Less chondrocyte death would permit increased use of thermal chondroplasty.

N-isopropylacrylamide-based Copolymers with Time-dependent LCST for a Bioresorbable Carrier

2004 ◽  
Vol 845 ◽  
Author(s):  
Bae Hoon Lee ◽  
Brent Vernon
Keyword(s):  
Body Temperature ◽  
Time Dependent ◽  
Solution Temperature ◽  
Gelation Temperature ◽  
Critical Solution Temperature ◽  
New Class ◽  
Polymeric Biomaterials ◽  
Localized Delivery ◽  
Hydrolysis Of

ABSTRACTTo develop a new class of in situ-forming, injectable, and biodegradable polymeric biomaterials based on time-dependent lower critical solution temperature (LCST) properties for localized delivery, copolymers of N-isopropylacrylamide (NIPAAm), 2-hydroxyethyl methacryl lactate (HEMA-lactate) and acrylic acid (AAc) were prepared with varying mole ratios of monomers. The copolymers showed LCST and gelation properties below body temperature in 0.1 N PBS solution of pH 7.4. The LCST and gelation temperature of the copolymers decreased as the HEMA-lactate content of the copolymers was increased. The copolymers also showed time-dependent LCST and gelation properties in 0.1 N PBS solution of pH 7.4 owing to hydrolysis of HEMA-lactate. Hydrolysis of HEMA-lactate caused the polymers to be more hydrophilic, resulting in an increase in LCST and gelation temperature. All the polymers with about 6 mol % AAc exhibited LCST and gelation temperature above body temperature after complete hydrolysis of HEMA-lactate.

EP.TH.299Is peritoneal lavage with water the optimal washout as a preventative method for peritoneal disease following colorectal cancer resection? A systematic review

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Nadia Youssef ◽  
James Beddingham ◽  
Faris Soliman ◽  
Keshav Swarnkar
Keyword(s):  
Colorectal Cancer ◽  
Patient Outcomes ◽  
Peritoneal Lavage ◽  
Experimental Studies ◽  
Cell Lysis ◽  
Peritoneal Disease ◽  
Cancer Resection ◽  
Colorectal Cancer Resection ◽  
Lavage Solution

Abstract Aim To study available data on the advantages of peritoneal lavage with distilled water following colorectal cancer resection in improving overall patient outcomes Methods PubMed, Google Scholar, and Cochrane databases were searched until October 2020. References from relevant articles were reviewed to widen the search. Results Overall, 3 experimental studies were identified. Water was found to be superior to other peritoneal lavage solutions in inducing tumorigenic cell lysis in vitro. Mice who underwent peritoneal lavage with water survived longer and had a significantly reduced peritoneal tumour burden compared to mice who did not undergo lavage or those treated with saline lavage solution. Peritoneal secretions were found to contaminate water lavage and reduce its cell-lytic effect. Nonetheless, complete cell lysis was achieved, in vivo, by prolonging the time of cell exposure to contaminated lavage solution by 20 min. Conclusion Single peritoneal lavage with water is probably safe and may have a positive influence on patient outcomes. Further evidence is required to regard sequential peritoneal lavages with water as beneficial and safe in humans.

Studies on Cyanide and Thiocyanate in Uraemia

1981 ◽  
Vol 4 (2) ◽  
pp. 60-61 ◽  
Author(s):  
H. Yatzidis ◽  
D. Koutsicos ◽  
D. Vlassopoulos ◽  
D. Cristodoulou ◽  
G. Yulis
Keyword(s):  
Renal Failure ◽  
Peritoneal Lavage ◽  
Terminal Renal Failure ◽  
Chronic Uraemia ◽  
Normal People ◽  
Lavage Solution

Cyanide and thiocyanate was measured in blood and in peritoneal lavage solution in patients with advanced or terminal renal failure. The behavior of these substances was comparable to that of normal people. Our finding does not support the hypothesis of an indirect toxicity of urea via its previous conversion to cyanate. Cyanate ion has not been implicated in the toxic status of chronic uraemia.

scholarly journals The Effects of Irrigation Solution Temperature on Body Temperature in Transurethral Surgeries

2017 ◽  
Vol 37 (3) ◽  
pp. 109-113 ◽  
Author(s):  
Can AKSU ◽  
A. Dilek İÇLİ ◽  
Kamil TOKER ◽  
Z. Mine SOLAK
Keyword(s):  
Body Temperature ◽  
Solution Temperature ◽  
Irrigation Solution

scholarly journals Alginate-g-PNIPAM-Based Thermo/Shear-Responsive Injectable Hydrogels: Tailoring the Rheological Properties by Adjusting the LCST of the Grafting Chains

2021 ◽  
Vol 22 (8) ◽  
pp. 3824
Author(s):  
Konstantinos Safakas ◽  
Sofia-Falia Saravanou ◽  
Zacharoula Iatridi ◽  
Constantinos Tsitsilianis
Keyword(s):  
Body Temperature ◽  
Rheological Properties ◽  
Sol Gel ◽  
Aqueous Media ◽  
Random Copolymer ◽  
Solution Temperature ◽  
Self Assembling ◽  
Potential Applications ◽  
Weak Gel ◽  
Phosphate Buffered Saline

Graft copolymers of alginate backbone and N-isopropylacrylamide/N-tert-butylacrylamide random copolymer, P(NIPAMx-co-NtBAMy), side chains (stickers) with various NtBAM content were designed and explored in aqueous media. Self-assembling thermoresponsive hydrogels are formed upon heating, in all cases, through the hydrophobic association of the P(NIPAMx-co-NtBAMy) sticky pendant chains. The rheological properties of the formulations depend remarkably on the NtBAM hydrophobic content, which regulates the lower critical solution temperature (LCST) and, in turn, the stickers’ thermo-responsiveness. The gelation point, Tgel, was shifted to lower temperatures from 38 to 20 °C by enriching the PNIPAM chains with 20 mol % NtBAM, shifting accordingly to the gelation temperature window. The consequences of the Tgel shift to the hydrogels’ rheological properties are significant at room and body temperature. For instance, at 37 °C, the storage modulus increases about two orders of magnitude and the terminal relaxation time increase about 10 orders of magnitude by enriching the stickers with 20 mol % hydrophobic moieties. Two main thermo-induced behaviors were revealed, characterized by a sol–gel and a weak gel–stiff gel transition for the copolymer with stickers of low (0.6 mol %) and high (14, 20 mol %) NtBAM content, respectively. The first type of hydrogels is easily injectable, while for the second one, the injectability is provided by shear-thinning effects. The influence of the type of media (phosphate buffer (PB), phosphate-buffered saline (PBS), Dulbecco’s modified Eagle’s medium (DMEM)) on the hydrogel properties was also explored and discussed. The 4 wt % NaALG-g-P(NIPAM80-co-NtBAM20)/DMEM formulation showed excellent shear-induced injectability at room temperature and instantaneous thermo-induced gel stiffening at body temperature, rendering it a good candidate for cell transplantation potential applications.

Scanning Electron Microscopy and X-Ray Analyses of Dental Tissues from a Hibernator

1976 ◽  
Vol 34 ◽  
pp. 178-179
Author(s):  
M. L. Zimny ◽  
A. C. Haller
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Body Temperature ◽  
Ground Squirrel ◽  
Alveolar Bone ◽  
X Ray ◽  
Dental Tissues ◽  
Bone Minerals ◽  
Apical Tooth ◽  
Scanning Electron

During hibernation the ground squirrel is immobile, body temperature reduced and metabolism depressed. Hibernation has been shown to affect dental tissues varying degrees, although not much work has been done in this area. In limited studies, it has been shown that hibernation results in (1) mobilization of bone minerals; (2) deficient dentinogenesis and degeneration of alveolar bone; (3) presence of calculus and tears in the cementum; and (4) aggrevation of caries and pulpal and apical tooth abscesses. The purpose of this investigation was to study the effects of hibernation on dental tissues employing scanning electron microscopy (SEM) and related x-ray analyses.

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