The consequences of vaccination with the Johne's disease vaccine, Gudair, on diagnosis of bovine tuberculosis

2012 ◽  
Vol 172 (10) ◽  
pp. 266-266 ◽  
Author(s):  
M. Coad ◽  
D. J. Clifford ◽  
H. M. Vordermeier ◽  
A. O. Whelan
Keyword(s):  
Bovine Tuberculosis ◽  
Johne's Disease ◽  
Johne’S Disease

Association between results of diagnostic tests for bovine tuberculosis and Johne’s disease in cattle

2019 ◽  
Vol 185 (22) ◽  
pp. 693-693 ◽  
Author(s):  
Catalina Picasso-Risso ◽  
Ana Grau ◽  
Douwe Bakker ◽  
Jesus Nacar ◽  
Olga Mínguez ◽  
...  
Keyword(s):  
Bovine Tuberculosis ◽  
Diagnostic Tests ◽  
Conditional Logistic Regression ◽  
Johne's Disease ◽  
Johne’S Disease ◽  
Effective Control ◽  
Mixed Effect ◽  
Intradermal Testing ◽  
Herd Level ◽  
The Impact

BackgroundBovine tuberculosis (bTB) diagnosis is impaired by numerous factors including cross-reactivity with Mycobacterium avium subspecies paratuberculosis, which causes Johne’s disease (JD). In addition, the effect of repeated bTB-intradermal testing on the performance of JD diagnostic tests is not fully understood. This study aimed to evaluate the impact of repeated bTB-intradermal tests under field conditions in Spain on the JD serological status of cattle.MethodsbTB-positive herds (n=264) from Castilla-y-Leon region were selected and matched with officially tuberculosis-free control herds. The association between JD and bTB status at the herd level was assessed using conditional logistic regression and, in herds with both JD-positive and bTB-positive animals, a Bayesian hierarchical mixed-effect model was used for individual-level analysis.ResultsA significantly higher risk of being JD positive (OR: 1.48; 95 per cent CI: 1.01 to 2.15) was found for bTB-positive herds compared with controls. Individual results indicated that cattle tested more than three times per year, within the last 90 days and more than 12 months were more likely to be JD positive. A skin test-related boost in antibody response could be the cause of an apparent increase of the sensitivity of the JD-absorbed ELISA.ConclusionThe results demonstrate the interaction between bTB repeated testing and JD individual and herd-level results and this improved knowledge will facilitate the design of more effective control programmes in herds coinfected with two of the most important endemic diseases affecting cattle in Spain.

scholarly journals Testing cattle with Johnin: Being a report on the value of the intradermal test on cattle

1941 ◽  
Vol 41 (3) ◽  
pp. 297-319 ◽  
Author(s):  
Keyword(s):  
Bovine Tuberculosis ◽  
Johne's Disease ◽  
Johne’S Disease ◽  
Intradermal Test ◽  
Post Mortem ◽  
Wasting Disease ◽  
Post Mortem Examination ◽  
Prominent Symptom

In the last century a wasting disease of cattle in which diarrhoea was the prominent symptom was described by some veterinarians, but was at first often confused with tuberculosis although the distinctive lesions found in the latter disease were not present at post-mortem examination. However, it is only during the last forty years that Johne's disease has been clearly differentiated from bovine tuberculosis.

scholarly journals The immunoregulatory effects of co-infection with Fasciola hepatica : From bovine tuberculosis to Johne's disease

2017 ◽  
Vol 222 ◽  
pp. 9-16 ◽  
Author(s):  
Amalia Naranjo Lucena ◽  
Laura Garza Cuartero ◽  
Grace Mulcahy ◽  
Annetta Zintl
Keyword(s):  
Bovine Tuberculosis ◽  
Fasciola Hepatica ◽  
Johne's Disease ◽  
Johne’S Disease

scholarly journals The development and use of Actiphage ® to detect viable mycobacteria from bovine tuberculosis and Johne’s disease‐infected animals

2020 ◽  
Vol 13 (3) ◽  
pp. 738-746 ◽  
Author(s):  
Benjamin M. C. Swift ◽  
Nathan Meade ◽  
Elsa Sandoval Barron ◽  
Malcolm Bennett ◽  
Tania Perehenic ◽  
...  
Keyword(s):  
Bovine Tuberculosis ◽  
Johne's Disease ◽  
Johne’S Disease

scholarly journals Driving Adoption and Commercialization of Subunit Vaccines for Bovine Tuberculosis and Johne’s Disease: Policy Choices and Implications for Food Security

Vaccines ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 667
Author(s):  
Albert I. Ugochukwu ◽  
Peter W. B. Phillips ◽  
Brian J. Ochieng’
Keyword(s):  
Food Security ◽  
Disease Prevention ◽  
Bovine Tuberculosis ◽  
Crop Production ◽  
Johne's Disease ◽  
Johne’S Disease ◽  
Animal Disease ◽  
Subunit Vaccines ◽  
Mycobacterium Avium Paratuberculosis ◽  
Global Food Security

Infectious animal diseases, such as Johne’s disease (JD) caused by Mycobacterium avium paratuberculosis (MAP) and bovine tuberculosis (bTB) caused by Mycobacterium bovis, have been a challenge to the livestock industry globally, impacting negatively on animal, human and environmental health, and overall food security. Despite several industry-led and government initiatives and programs aimed at preventing and reducing losses associated with JD and bTB outbreaks, JD has remained endemic in many parts of the world while there have been incidental outbreaks of bTB. While several studies focus on sustainable intensification of food (crop) production as a critical solution to food insecurity, following the existential interconnection between animals, humans and the environment recognized by one health, we frame food security through the lens of animal disease prevention and control, given the importance of livestock products to human health and livelihood. Vaccination has been a popular strategy successfully used in controlling other infectious diseases. The paper focuses on an alternate strategy of two subunit vaccines with companion diagnostics targeted at individual pathogens to attain satisfactory immunological responses for JD and bTB. We examine gaps in vaccine policies, commercialization, and potential strategies that would strengthen animal disease prevention and enhance food security. The potential of public–private partnership in strengthening private sector participation in effective animal disease control and health delivery and the implications for global food security are discussed.

scholarly journals Diagnostic interaction between bovine tuberculosis (bTB) and Johne's disease in bTB highly prevalent dairy farms of Uruguay

2019 ◽  
Vol 7 ◽  
pp. 100052 ◽  
Author(s):  
C. Picasso-Risso ◽  
A. Gil ◽  
A. Nunez ◽  
A. Suanes ◽  
V. Macchi ◽  
...  
Keyword(s):  
Bovine Tuberculosis ◽  
Dairy Farms ◽  
Johne's Disease ◽  
Johne’S Disease
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