scholarly journals Effect of theophylline on exercise performance in patients with severe chronic obstructive pulmonary disease.

Thorax ◽  
1994 ◽  
Vol 49 (4) ◽  
pp. 332-334 ◽  
Author(s):  
G Fink ◽  
C Kaye ◽  
J Sulkes ◽  
U Gabbay ◽  
S A Spitzer
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Exercise Performance ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease

Exercise Performance of Polycythemic Chronic Obstructive Pulmonary Disease Patients

CHEST Journal ◽  
1990 ◽  
Vol 98 (5) ◽  
pp. 1073-1077 ◽  
Author(s):  
Kota G. Chetty ◽  
Richard W. Light ◽  
David W. Stansbury ◽  
Norah Milne
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Exercise Performance ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease

scholarly journals Respiratory Consequences of Mild-to-Moderate Obesity: Impact on Exercise Performance in Health and in Chronic Obstructive Pulmonary Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Denis E. O'Donnell ◽  
Conor D. J. O'Donnell ◽  
Katherine A. Webb ◽  
Jordan A. Guenette
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Exercise Performance ◽  
Epidemiological Studies ◽  
Exercise Intolerance ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Exercise Limitation ◽  
Mechanical Constraints ◽  
The Impact

In many parts of the world, the prevalence of obesity is increasing at an alarming rate. The association between obesity, multiple comorbidities, and increased mortality is now firmly established in many epidemiological studies. However, the link between obesity and exercise intolerance is less well studied and is the focus of this paper. Although exercise limitation is likely to be multifactorial in obesity, it is widely believed that the respiratory mechanical constraints and the attendant dyspnea are important contributors. In this paper, we examined the evidence that critical ventilatory constraint is a proximate source of exercise limitation in individuals with mild-to-moderate obesity. We first reviewed existing information on exercise performance, including ventilatory and perceptual response patterns, in obese individuals who are otherwise healthy. We then considered the impact of obesity in patients with preexisting respiratory mechanical abnormalities due to chronic obstructive pulmonary disease (COPD), with particular reference to the effect on dyspnea and exercise performance. Our main conclusion, based on the existing and rather sparse literature on the subject, is that abnormalities of dynamic respiratory mechanics are not likely to be the dominant source of dyspnea and exercise intolerance in otherwise healthy individuals or in patients with COPD with mild-to-moderate obesity.

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