scholarly journals Ventilatory failure in Guillain-Barre syndrome: indications for assisted ventilation in neurological diseases

Thorax ◽  
1981 ◽  
Vol 36 (2) ◽  
pp. 159-160
Author(s):  
I. Grant ◽  
C Mawdsley ◽  
G K Crompton ◽  
E. Jellinek ◽  
R. Willey ◽  
...  
Keyword(s):  
Neurological Diseases ◽  
Assisted Ventilation ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Ventilatory Failure ◽  
Guillain Barré

Diaphragmatic Performance during Recovery from Acute Ventilatory Failure in Guillain-Barré Syndrome and Myasthenia Gravis

CHEST Journal ◽  
1991 ◽  
Vol 99 (2) ◽  
pp. 444-451 ◽  
Author(s):  
Cecil O. Borel ◽  
Charles Tilford ◽  
David G. Nichols ◽  
Daniel F. Hardey ◽  
Richard J. Traystman
Keyword(s):  
Myasthenia Gravis ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Ventilatory Failure ◽  
Guillain Barré

scholarly journals Reworsening of Recurrent Guillain-Barré Syndrome Triggered by COVID-19 Infection

2021 ◽  
Vol 15 (1) ◽  
pp. 48-51
Author(s):  
Gian Luca Vita ◽  
Carmen Terranova ◽  
Maria Sframeli ◽  
Antonio Toscano ◽  
Giuseppe Vita
Keyword(s):  
Viral Infection ◽  
Neurological Diseases ◽  
Intravenous Immunoglobulins ◽  
Guillain Barre Syndrome ◽  
Case Presentation ◽  
Appropriate Treatment ◽  
Immune Mediated ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Introduction: Guillain-Barré Syndrome (GBS) is an acute, immune-mediated, generalized polyradiculoneuropathy often triggered by a bacterial or viral infection, vaccination, or surgery. During the SARS-CoV-2 pandemic, some patients were reported with GBS associated COVID-19 infection. Case Presentation: We report, herein, a patient who had a recurrent GBS after forty years. Intravenous immunoglobulins (IVIg) induced improvement, but her condition worsened suddenly after twenty days, coinciding with a COVID-19 infection. A second IVIg cycle was administered, and she improved again. Conclusion: The take-home message is that in the current pandemic, any re-worsening or lack of improvement after appropriate treatment of GBS or possibly other autoimmune neurological diseases must be checked to determine if it is related to COVID-19 infection.

scholarly journals Ventilatory failure in the Guillain-Barre syndrome.

Thorax ◽  
1980 ◽  
Vol 35 (7) ◽  
pp. 557-558 ◽  
Author(s):  
M Massam ◽  
R S Jones
Keyword(s):  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Ventilatory Failure ◽  
Guillain Barré

Looks can be deceiving: three cases of neurological diseases mimicking Guillain–Barrè syndrome

2015 ◽  
Vol 37 (4) ◽  
pp. 541-545 ◽  
Author(s):  
G. Sciacca ◽  
A. Nicoletti ◽  
S. Lo Fermo ◽  
G. Mostile ◽  
C. Giliberto ◽  
...  
Keyword(s):  
Neurological Diseases ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals Therapeutic Plasma Exchange – A 2 Years Experience at a Tertiary Care Centre in Mumbai, Maharashtra, India

2021 ◽  
Vol 10 (15) ◽  
pp. 1069-1073
Author(s):  
Moni Mukesh Udani ◽  
Akanksha Jivrag Neogi ◽  
Shweta Wasudeo Dhote ◽  
Iqbal Singh
Keyword(s):  
Plasma Exchange ◽  
Neurological Diseases ◽  
Tertiary Care ◽  
Complete Recovery ◽  
Therapeutic Plasma Exchange ◽  
Effective Procedure ◽  
Guillain Barre Syndrome ◽  
Tertiary Care Centre ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

BACKGROUND Therapeutic plasma exchange is a process where the blood collected from patient is passed through an apheresis instrument where the plasma is removed and discarded and reinfusion of blood cells done with replacement fluids like plasma or albumin to the patient.1 It is to remove pathogenic autoantibodies, immune complexes, cryoglobulins and toxins present in the plasma. Plasma exchange is considered effective and cheaper immunomodulatory treatment when compared to intravenous immunoglobulin (IVIG). 2 We present our institutional experience with therapeutic plasma exchange (TPE) in treatment of various non-neurological and neurological diseases. Our study was conducted to assess the indications, complications and outcome of TPE in the treatment of patients. METHODS A retrospective study of TPE procedures was carried out in the Department of Immunohaematology and blood transfusion, M.G.M Medical College and Hospital, Navi Mumbai from June 2018 to June 2020. A total of 45 procedures were performed among 13 patients between 4 years of age to 66 years of age. Clinical parameters were checked, and laboratory investigations were done before the procedure. Data was collected from the requisition forms by the clinicians and the apheresis database. RESULTS A total of 47 procedures were carried out among 13 patients. TPE is a safe and effective procedure for treating patients with neurologic and non-neurological diseases. Most common indication was Guillain Barre syndrome followed by myasthenia gravis. Incidence of adverse reactions was 7.6 %. CONCLUSIONS TPE is a safe and effective procedure for treating patients with neurologic and nonneurological diseases. It benefited 10 out of 13 patients, and they showed complete recovery. KEY WORDS Therapeutic Plasma Exchange, Guillain Barre syndrome

scholarly journals Therapeutic Plasma Exchange in Guillain Barre Syndrome: An experience of Bangabanhu Sheikh Mujib Medical University, Bangladesh

2022 ◽  
Vol 4 (1) ◽  
pp. 11-13
Author(s):  
Sheikh Saiful Islam ◽  
Jannatul Ferdous ◽  
Ashraful Hoque ◽  
Atiar Rahman
Keyword(s):  
Plasma Exchange ◽  
Treatment Modality ◽  
Neurological Diseases ◽  
Treatment Options ◽  
Therapeutic Plasma Exchange ◽  
Guillain Barre Syndrome ◽  
Treatment Modalities ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Medical University

Background: Therapeutic plasma exchange (TPE) has been used as one of the treatment modalities of neurological diseases. Intravenous Immunoglobulin (IVIG) and Therapeutic Plasma Exchange (TPE)are treatment options in Guillain Barre syndrome (GBS). In developing countries IVIG is not easily available and it is also expensive, TPE is preferred for treatment of GBS as it is affordable. Study on TPE for GBS are scarce here. Most of the study regarding TPE in GBS has been conducted in high –income countries as it is expensive treatment modality. Reports on TPE in GBS is very scared from Bangladesh. Materials and Methods: A retrospective analysis of TPE with a standard hemolysis equipment for the treatment of Guillain Barre syndrome (GBS) was conducted A 50 patients of GBS who received TPE conducted between January 2017 to December 2018 in the department of Transfusion Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh were analyzed. All patients had underdone at least 2 cycles of plasma exchange. Volume exchanged in each cycle was one plasma volume. Results: Out of 50 cases there were 43 (86%) male and 7 (14%) female.  Age range of patients was from 11 – 50 years. Approximately 40% improved clinically of first cycle of PE & 85% after second cycle, 95% after third cycle and 95-100% after 5 cycle. 1(2%) patient died, and 49(98%) patients survived and recovered. Conclusion: The treatment is cost affection in Compassion to IVIG. TPE is and affection, safe and affordable treatment modality for GBS.

Relationship of Glycemic Status with Disease Severity in Guillain-Barré Syndrome

2020 ◽  
Vol 6 (2) ◽  
pp. 96-100
Author(s):  
Mohammad Akter Hossain ◽  
Mashfiqul Hasan ◽  
Mohammad Atiqur Rahman ◽  
Murshed Baqui ◽  
Mahmudul Islam ◽  
...  
Keyword(s):  
Disease Severity ◽  
Cross Sectional Study ◽  
Assisted Ventilation ◽  
Guillain Barre Syndrome ◽  
Disability Score ◽  
Cross Sectional ◽  
Sum Score ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Relationship Of

Background: Guillain-Barré syndrome (GBS) is an acute autoimmune polyneuroradiculopathy characterized by flaccid paralysis which may lead to respiratory failure requiring intensive care. Objective: The purpose of the present study was to explore the relationship between the fasting plasma glucose (FPG), hemoglobin A1c (HbA1c) and disease severity of GBS patients who are not known to have DM. Methodology: This cross-sectional study included adult GBS patients without having DM [age 35 (22-48) years, median (interqurtile range, IQR); 39 male 22 female] who were admitted to Neurology department, National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from July 2018 to June 2019. Demographics, clinical data were noted and FPG, HbA1c were measured. Disease severity were assessed by the GBS disability scale ranging from 0 to 6 with increasing score reflecting increased disability. Results: Patients with more severe GBS (disability score ≥4, unable to walk) had higher frequency of elevated FPG >5.5 mmol/L (61.2%; 30/49) in comparison to those with less severe GBS (disability score ≤3, able to walk; FPG >5.5 mmol/L in 16.7%, 2/12; p=0.006). But distribution of HbA1c category was not different across the groups (disability score ≥4 vs. ≤3: HbA1c <5.7: 40% vs. 58%; 5.7-6.4: 50% vs. 25%; >6.4: 10% vs. 17%; p=0.296). Participants with elevated FPG were elder [elevated vs. normal FPG: 40 (28-54) vs. 25 (19-43) years; median (IQR), p=0.012] and had higher CSF glucose (p=0.002) than those with normal FPG, but there was no difference in respct of gender, MRC sum score, requirement of assisted ventilation, CSF protein, GBS subtypes and duration of hospital stay (p=not significant for all). Conclusions: Patients with severe GBS have higher frequency of elevated FPG but not HbA1c. An acute change in glucose metabolism may occur in GBS which needs further study. Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 96-100

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