scholarly journals Haemolysis related to mitral valve replacement with the Beall valve prosthesis

Thorax ◽  
1973 ◽  
Vol 28 (4) ◽  
pp. 488-491 ◽  
Author(s):  
B. J. Henderson ◽  
A. S. Mitha ◽  
B. T. le Roux ◽  
M. S. Gotsman
Keyword(s):  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Valve Prosthesis

Mitral Valve Replacement

1968 ◽  
Vol 13 (9) ◽  
pp. 285-292
Author(s):  
J. M. Reid ◽  
R. S. Barclay ◽  
J. G. Stevenson ◽  
T. M. Welsh ◽  
N. McSwan
Keyword(s):  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Average Duration ◽  
Valve Prosthesis ◽  
Mortality And Morbidity ◽  
Dramatic Decline ◽  
Mitral Incompetence ◽  
Heart Size

A series of 78 patients with advanced mitral incompetence treated by mitral valve replacement with a Starr-Edwards prosthesis is reported. The overall early mortality was 24 (30.7 per cent) and a further 3 died later. The causes of these early and late deaths are fully analysed. Most occurred in the early part of the series, and there has been a dramatic decline in both mortality and morbidity in the later cases since adoption of continuous clamping of the ascending aorta during the period necessary for excising the valve and suturing the prosthesis in position. The average duration of aortic clamping has been 20 minutes. During the last year (1967) there have been only 5 deaths in 32 patients, representing a mortality of 15.6 per cent. It is emphasised that only patients who have severe incapacity due to mitral incompetence require operation, and neither age nor the degree of pulmonary vascular resistance is a bar to surgery. Advanced renal disease, generalised pulmonary emphysema, and recent myocardial infarction are the only three absolute contraindications. The 54 survivors from operation have been closely supervised for periods varying from several months to as long as 4 years, and as mentioned above 3 have died during this time. The remaining 51 have shown a striking improvement in exercise tolerance, with reduction in heart size. The various surgical procedures available for dealing with mitral incompetence are discussed. Plication of the valve would appear in our experience to be limited to a small number with non-calcific, mildly sclerotic, and only slightly distorted valves. Pig aortic heterografts or pulmonary autografts may offer scope in the future, but we contend that the Starr-Edwards ball-valve prosthesis, although admittedly not as yet ideal, is the best available at present. With the introduction of the latest modification of this valve (now marketed in Britain), thrombo-embolic phenomena should be reduced to a minimum.

scholarly journals Testing of delivery system for transcatheter mitral valve implantation

2018 ◽  
Vol 22 (4) ◽  
pp. 80
Author(s):  
R. M. Sharifulin ◽  
A. V. Bogachev-Prokophiev ◽  
I. Yu. Zhuravleva ◽  
T. P. Timchenko ◽  
I. S. Zykov ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Delivery System ◽  
Conflict Of Interest ◽  
Laboratory Animal ◽  
Valve Prosthesis ◽  
Transcatheter Mitral Valve Replacement ◽  
Animal Implantation

<p><strong>Aim.</strong> The aim of the study was to evaluate a prototype of a delivery system for transcatheter mitral valve replacement in vitro and in laboratory animal implantation. <br /><strong>Methods.</strong> The prototypes of the delivery system and transcatheter mitral valve prosthesis were evaluated in vitro in an isolated pig heart using transapical access. In an experiment on a large laboratory animal implantation was performed using transatrial access.<br /><strong>Results.</strong> It was found out that the prototype of the delivery system allows to adequately deliver and release the transcatheter prosthesis in implantation zone using transatrial and transapical approaches without frame deformation and valve dysfunction. <br />Conclusion. The delivery system prototype for transcatheter mitral valve replacement demonstrated satisfactory characteristics during in vitro experiment and large laboratory animal implantation.</p><p>Received 26 November 2018. Revised 17 December 2018. Accepted 21 December 2018.</p><p><strong>Funding:</strong> The study was carried out with the support of a grant of the Russian Science Foundation No. 16-15-10315.</p><p><strong>Conflict of interest:</strong> Author declare no conflict of interest.</p><p><strong>Author contributions</strong><br />Conception and study design: I.Y. Zhuravleva <br />Data collection and analysis: T.P. Timchenko, M.A. Ovcharov, E.V. Boyarkin <br />Drafting the article: R.M. Sharifulin, I.S. Zykov <br />Critical revision of the article: A.V. Bogachev-Prokophiev, A.M. Karaskov<br />Final approval of the version to be published: R.M. Sharifulin, A.V. Bogachev-Prokophiev, I.Y. Zhuravleva, T.P. Timchenko, I.S. Zykov, E.V. Boyarkin, M.A. Ovcharov, A.M. Karaskov</p>

scholarly journals First-in-man transapical mitral valve replacement using the Direct Flow Medical®aortic valve prosthesis :

2015 ◽  
Vol 36 (31) ◽  
pp. 2119-2119 ◽  
Author(s):  
Fritz Mellert ◽  
Jan-Malte Sinning ◽  
Nikos Werner ◽  
Armin Welz ◽  
Eberhard Grube ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Aortic Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Valve Prosthesis ◽  
Direct Flow ◽  
Aortic Valve Prosthesis
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