scholarly journals The expression and function of Epstein-Barr virus encoded latent genes

2000 ◽  
Vol 53 (5) ◽  
pp. 238-247 ◽  
Author(s):  
L S Young
Keyword(s):  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr ◽  
And Function

scholarly journals Helper cell-independent cytotoxic clones in man.

1982 ◽  
Vol 156 (6) ◽  
pp. 1854-1859 ◽  
Author(s):  
S L Wee ◽  
L K Chen ◽  
G Strassmann ◽  
F H Bach
Keyword(s):  
T Cell ◽  
Epstein Barr Virus ◽  
Helper Cell ◽  
Cytotoxic T Cell ◽  
Lymphoblastoid Cell Lines ◽  
Barr Virus ◽  
Mediate Cytotoxicity ◽  
Epstein Barr ◽  
And Function

We report here a class of helper cell-independent cytotoxic T cell (HITc) clones in man that can proliferate in response to antigenic stimulation as well as mediate cytotoxicity. HITc appear to be rare among clones derived from primary in vitro allosensitized culture, but constitute the majority of clones derived from cells sensitized to autologous Epstein-Barr virus-transformed lymphoblastoid cell lines. The implications of the derivation and function of HITc clones are discussed.

RelA and RelB cross-talk and function in Epstein–Barr virus transformed B cells

Leukemia ◽  
2013 ◽  
Vol 28 (4) ◽  
pp. 871-879 ◽  
Author(s):  
A Chanut ◽  
F Duguet ◽  
A Marfak ◽  
A David ◽  
B Petit ◽  
...  
Keyword(s):  
B Cells ◽  
Cross Talk ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr ◽  
And Function

scholarly journals Perturbation of biogenesis and targeting of Epstein–Barr virus-encoded miR-BART3 microRNA by adenosine-to-inosine editing

2013 ◽  
Vol 94 (12) ◽  
pp. 2739-2744 ◽  
Author(s):  
Ting Lei ◽  
Kit-San Yuen ◽  
Sai Wah Tsao ◽  
Honglin Chen ◽  
Kin-Hang Kok ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Carcinoma Cells ◽  
Seed Region ◽  
Mrna Editing ◽  
Barr Virus ◽  
Mature Micrornas ◽  
Epstein Barr ◽  
And Function ◽  
Editing Enzyme

Epstein–Barr virus (EBV) encodes at least 44 mature microRNAs (miRNAs), some of which are abundantly expressed in nasopharyngeal carcinoma cells. EBV-encoded miR-BART6 miRNA is known to undergo adenosine-to-inosine (A-to-I) RNA editing, which impacts on processing and function. Whether additional EBV miRNAs might be A-to-I edited remains to be determined. In this study, we have reported on A-to-I editing of EBV miR-BART3. The A-to-I editing enzyme was expressed abundantly in EBV-infected epithelial carcinoma cells. pri-miR-BART3 was found to be edited at four sites in these cells and in nasopharyngeal carcinoma samples. Whereas editing of the second site located within the seed region prevented the targeting of DICE1 mRNA, editing of the third site effectively crippled the biogenesis of mature miR-BART3. Thus, A-to-I editing perturbs biogenesis and targeting of miR-BART3 and may contribute to its differential expression and function in EBV-infected epithelial cells.

scholarly journals Structure and function of the Epstein-Barr virus BZLF1 protein.

1990 ◽  
Vol 64 (5) ◽  
pp. 2110-2116 ◽  
Author(s):  
G Packham ◽  
A Economou ◽  
C M Rooney ◽  
D T Rowe ◽  
P J Farrell
Keyword(s):  
Epstein Barr Virus ◽  
Structure And Function ◽  
Barr Virus ◽  
Epstein Barr ◽  
And Function

Reactivation of Epstein-Barr virus: regulation and function of the BZLF1 gene

1997 ◽  
Vol 5 (10) ◽  
pp. 399-405 ◽  
Author(s):  
Samuel H. Speck ◽  
T. Chatila ◽  
E. Flemington
Keyword(s):  
Epstein Barr Virus ◽  
Barr Virus ◽  
Bzlf1 Gene ◽  
Epstein Barr ◽  
And Function

scholarly journals Comparison of the EBNA1 Proteins of Epstein–Barr Virus and Herpesvirus Papio in Sequence and Function

Virology ◽  
1996 ◽  
Vol 222 (1) ◽  
pp. 1-13 ◽  
Author(s):  
John L. Yates ◽  
Sarah M. Camiolo ◽  
Sayed Ali ◽  
Angela Ying
Keyword(s):  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr ◽  
And Function
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