scholarly journals SURFING FOR NEUROLOGICAL INFECTION

2004 ◽  
Vol 75 (90001) ◽  
pp. 50i-50
Author(s):  
C Douglass
Author(s):  
Schlindwein Marco Antônio Machado ◽  
Breis Letícia Caroline ◽  
Bandeira Isabelle Pastor ◽  
Gonçalves Marcus Vinicius Magno

Author(s):  
Digant Patni ◽  
Vishal R. Munjal

<p class="abstract"><strong>Background:</strong> Tracheostomy is frequently performed surgical procedure. The present study was carried out to assess data on various indications, surgical issues if any, complications and outcomes of paediatric tracheostomy.</p><p class="abstract"><strong>Methods:</strong> This study is a retrospective analysis of 32 paediatric patients between 1 to 12 years of age, who underwent tracheostomy at SAIMS, Indore between June 2015 to June 2019. Data was analysed in terms of patient age, sex, emergency or planned procedure, any surgical challenge, complications and post-operative follow up.  </p><p class="abstract"><strong>Results:</strong> Majority of patients were of prolonged intubation due to respiratory and laryngotracheobronchitis (15.6%) each, neuromuscular disease (15.6%), seizure disorder (9.4%), metabolic disease (9.4%) and neurological infection (6.3%). Obstructive causes included head injury (9.4%), sub-glottic stenosis (6.3%), malignancy (6.3%) and craniofacial anomaly (3.1%). Common complication encountered were partial blockage of tube, peri-stomal granulation and accidental decannulation. There was no tracheostomy related mortality in this study. Out of 32 patients, 16 were successfully decannulated, 6 were lost to follow up, 6 could not be decannulated and 4 expired due to worsening of primary disease.</p><p class="abstract"><strong>Conclusions:</strong> There is a changing trend in indications of tracheostomy and overall complications have reduced due to trained team and better care facility.</p>


Author(s):  
Tom Solomon ◽  
Benedict Michael

Neurological infections can be broadly subdivided into chronic/subacute and acute. Chronic/subacute infection usually presents with global cognitive decline, with the prototypical disease being progressive multifocal leucoencephalopathy due to infection with the JC virus in immunocompromised patients. Acute neurological infections can be defined microbiologically, by the nature of the pathogen; clinically, by the presenting signs and symptoms and initial CSF findings; or anatomically. The anatomical definitions are those occurring intracranially (‘meningitis’, where infection involves the meninges overlying the brain; ‘encephalitis’, where the brain parenchyma is involved; or ‘cerebral abscesses’) and those affecting the spinal cord (‘myelitis’). However, there is often both clinical and histological overlap between these syndromes; consequently, the terms ‘meningoencephalitis’ and ‘encephalomyelitis’ are often used. Patients with acute intracranial CNS infections provide the greatest challenge to general physicians, because urgent investigation and appropriate treatment can save lives; they therefore form the focus of this chapter.


2006 ◽  
Vol 37 (4) ◽  
pp. 293-299 ◽  
Author(s):  
Alicia Susana Mistchenko ◽  
Mariana Viegas ◽  
Maria Paula Della Latta ◽  
Paola Roxana Barrero

2006 ◽  
Vol 55 (2) ◽  
pp. 139-142 ◽  
Author(s):  
Eriques Gonçalves da Silva ◽  
Francisco de Assis Baroni ◽  
Flavio César Viani ◽  
Luciana da Silva Ruiz ◽  
Rinaldo Ferreira Gandra ◽  
...  

To evaluate the virulence profile of strains of Cryptococcus neoformans var. grubii, 62 strains of this yeast were inoculated into BALB/c mice. It was found that 69 % of the strains were significantly more lethal to the mice and were recovered from a higher percentage (60 %) of the organs compared with the other 31 % of the strains, which were recovered from 35 % of organs tested. Those strains that provoked higher death rates were also recovered from the central nervous system at a higher rate (84 %) than the less lethal strains (32 %). This finding led to an investigation of the factors that enhanced the capacity for neurological infection and death of the animals. The results of this study suggested that environmental strains present different degrees of virulence. The correlation of exoenzyme production before and after inoculation and between the groups of mice indicated that exoenzyme production had no influence on differences in virulence among the strains studied.


Author(s):  
Ellen Tedford ◽  
Glenn McConkey

Although the parasite Toxoplasma gondii is one of the most pervasive neurotropic pathogens in the world, the host-parasite interactions during CNS infection and consequences of neurological infection are just beginning to be unraveled. The chronic stages of infection have been considered dormant, although several studies have found correlations of infection with an array of host behavioral changes. These may facilitate parasite transmission and impact neurological diseases. During infection, in addition to the presence of the parasites within neurons, host-mediated neuroimmune and hormonal responses to infection are also present. T. gondii induces numerous changes to host neurons during infection and globally alters host neurological signaling pathways, as discussed in this review. Understanding the neurophysiological changes in the host brain is imperative to understanding the parasitic mechanisms and to delineate the effects of this single-celled parasite on health and its contribution to neurological disease.


2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Pushkar Singh Rawat ◽  
Kajal Patel ◽  
Sudhir Mehrotra

Japanese encephalitis (JE) is neurological infection which is caused by Japanese encephalitis virus (JEV), a flavivirus, and is closely related to St. Louis encephalitis and West Nile encephalitis. It is predominant in rural areas of Asia, which spread through bites of culicine mosquitoes, most often Culex tritaeniorhynchus. JE has broad range of manifestations. It can range from subtle changes in behavior to serious problems, including blindness, ataxia, weakness, and movement disorders.Japanese encephalitis virus is endemic in 24 countries in Southeast Asia and Western Pacific regions with more than 3 billion people at risk of infection. JE is the main cause of viral encephalitis in people in many countries of Asia amounting almost 68,000 clinical cases per year. Children are at greatest risk, with adults in endemic areas having protective immunity as a consequence of childhood infection. This disease is of particular importance in Gorakhpur, eastern belt of UP, the state with the largest population in India, where a large number of children have been dying in the past several years with alarming frequency since 1978.


1998 ◽  
Vol 36 (7) ◽  
pp. 2103-2104 ◽  
Author(s):  
Marcello Valassina ◽  
Anna Maria Cuppone ◽  
Silvia Bianchi ◽  
Laura Santini ◽  
Maria Grazia Cusi

The Toscana virus can cause neurological infection in adults. This study of 112 cases of acute meningitis which occurred during the summers of 1995, 1996, and 1997 demonstrated the presence of viral RNA in the cerebrospinal fluid of 56 patients. Their sequence analysis shows four variants of the Toscana virus.


Sign in / Sign up

Export Citation Format

Share Document