scholarly journals Is immunising all patients with chronic lung disease in the community against influenza cost effective? Evidence from a general practice based clinical prospective cohort study in Utrecht, The Netherlands

1998 ◽  
Vol 52 (2) ◽  
pp. 120-125 ◽  
Author(s):  
E. Hak ◽  
G. A. van Essen ◽  
E. Buskens ◽  
W. Stalman ◽  
R. A. de Melker
Keyword(s):  
General Practice ◽  
Cohort Study ◽  
The Netherlands ◽  
Lung Disease ◽  
Prospective Cohort Study ◽  
Chronic Lung Disease ◽  
Prospective Cohort ◽  
Cost Effective

Chronic Lung Disease and Mortality after Cardiac Surgery: A Prospective Cohort Study

2018 ◽  
Vol 32 (5) ◽  
pp. 2241-2245 ◽  
Author(s):  
Dmitry Ponomarev ◽  
Oksana Kamenskaya ◽  
Asya Klinkova ◽  
Irina Loginova ◽  
Pavel Vedernikov ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Cohort Study ◽  
Lung Disease ◽  
Prospective Cohort Study ◽  
Chronic Lung Disease ◽  
Prospective Cohort

scholarly journals The course of newly presented unexplained complaints in general practice patients: a prospective cohort study

2009 ◽  
Vol 26 (6) ◽  
pp. 455-465 ◽  
Author(s):  
H Koch ◽  
M. van Bokhoven ◽  
P. Bindels ◽  
T van der Weijden ◽  
G. Dinant ◽  
...  
Keyword(s):  
General Practice ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort

scholarly journals Dyspnoea as a predictor of cause-specific heart/lung disease mortality in Bangladesh: a prospective cohort study

2016 ◽  
Vol 70 (7) ◽  
pp. 689-695 ◽  
Author(s):  
Gene R Pesola ◽  
Maria Argos ◽  
Vernon M Chinchilli ◽  
Yu Chen ◽  
Faruque Parvez ◽  
...  
Keyword(s):  
Cohort Study ◽  
Lung Disease ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Disease Mortality

scholarly journals The population-based Occupational and Environmental Health Prospective Cohort Study (AMIGO) in the Netherlands

BMJ Open ◽  
2014 ◽  
Vol 4 (11) ◽  
pp. e005858 ◽  
Author(s):  
Pauline Slottje ◽  
C Joris Yzermans ◽  
Joke C Korevaar ◽  
Mariëtte Hooiveld ◽  
Roel C H Vermeulen
Keyword(s):  
Cohort Study ◽  
The Netherlands ◽  
Environmental Health ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Population Based

scholarly journals High-Resolution Melting Is a Sensitive, Cost-Effective, Time-Saving Technique for BRAF V600E Detection in Thyroid FNAB Washing Liquid: A Prospective Cohort Study

2015 ◽  
Vol 4 (2) ◽  
pp. 73-81 ◽  
Author(s):  
Marco Marino ◽  
Maria Laura Monzani ◽  
Giulia Brigante ◽  
Katia Cioni ◽  
Bruno Madeo ◽  
...  
Keyword(s):  
Cohort Study ◽  
High Resolution ◽  
Molecular Analysis ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Large Scale ◽  
High Resolution Melting ◽  
Cost Effective ◽  
Braf V600e Mutation ◽  
Braf V600e

Objective: The diagnostic accuracy of thyroid fine needle aspiration biopsy (FNAB) can be improved by the combination of cytological and molecular analysis. In this study, washing liquids of FNAB (wFNAB) were tested for the BRAF V600E mutation, using the sensitive and cost-effective technique called high-resolution melting (HRM). The aim was to demonstrate the feasibility of BRAF analysis in wFNAB and its diagnostic utility, combined with cytology. Design: Prospective cohort study. Methods: 481 patients, corresponding to 648 FNAB samples, were subjected to both cytological (on cells smeared onto a glass slide) and molecular analysis (on fluids obtained washing the FNAB needle with 1 ml of saline) of the same aspiration. BRAF V600E analysis was performed by HRM after methodological validation for application to wFNAB (technique sensitivity: 5.4%). Results: The cytological results of the FNAB were: 136 (21%) nondiagnostic (THY1); 415 (64%) benign (THY2); 80 (12.4%) indeterminate (THY3); 9 (1.4%) suspicious for malignancy (THY4); 8 (1.2%) diagnostic of malignancy (THY5). The BRAF V600E mutation was found in 5 THY2, 2 THY3, 6 THY4 and 6 THY5 samples. Papillary carcinoma diagnosis was histologically confirmed in all BRAF+ thyroidectomized patients. BRAF combined with cytology improved the diagnostic value compared to cytology alone in a subgroup of 74 operated patients. Conclusions: HRM was demonstrated to be a feasible method for BRAF analysis in wFNAB. Thanks to its sensitivity and cost-effectiveness, it might be routinely used on a large scale in clinical practice. In perspective, standby wFNAB samples could be analyzed a posteriori in case of indeterminate cytology and/or suspicious findings on ultrasound.

scholarly journals High rates of general practice attendance by former prisoners: a prospective cohort study

2017 ◽  
Vol 207 (2) ◽  
pp. 75-80 ◽  
Author(s):  
Megan Carroll ◽  
Matthew J Spittal ◽  
Anna R Kemp‐Casey ◽  
Nicholas G Lennox ◽  
David B Preen ◽  
...  
Keyword(s):  
General Practice ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Former Prisoners
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