scholarly journals The sex differential in ischaemic heart disease: trends by social class 1931 to 1971.

1979 ◽  
Vol 33 (1) ◽  
pp. 74-77 ◽  
Author(s):  
M L Halliday ◽  
T W Anderson
The Lancet ◽  
1987 ◽  
Vol 330 (8552) ◽  
pp. 197-201 ◽  
Author(s):  
S.J. Pocock ◽  
D.G. Cook ◽  
A.G. Shaper ◽  
A.N. Phillips ◽  
M. Walker

1997 ◽  
Vol 90 (5) ◽  
pp. 247-249 ◽  
Author(s):  
J T Lear ◽  
R H Neary ◽  
P Jones ◽  
D A Fitzgerald ◽  
J S C English

For reasons that are unclear, patients with dermatitis herpetiformis (DH) have a lower than expected mortality rate from ischaemic heart disease. We have compared risk factors for ischaemic heart disease (lipids, fibrinogen levels, smoking history and social class) in 29 DH patients and 57 controls matched for age and sex. Patients with DH had significantly lower cholesterol, triglycerides, apolipoprotein B and fibrinogen and higher HDL2; they also smoked less and were of higher social class. The mechanisms underlying these observations merit further investigation. Intestinal abnormalities or gluten-free diet may account for differences in lipid fractions, and the immunomodulatory properties of cigarette smoke may protect against the development of DH.


2014 ◽  
Vol 5 (3) ◽  
pp. 164-170 ◽  
Author(s):  
A. Heshmati ◽  
I. Koupil

Studies on placental size and cardiovascular disease have shown inconsistent results. We followed 10,503 men and women born in Uppsala, Sweden, 1915–1929 from 1964 to 2008 to assess whether birth characteristics, including placental weight and placenta/birth weight ratio, were predictive of future ischaemic heart disease (IHD). Adjustments were made for birth cohort, age, sex, mother’s parity, birth weight, gestational age and social class at birth. Placental weight and birth weight were negatively associated with IHD. The effect of placental weight on IHD was stronger in individuals from medium social class at birth and in those with low education. Men and women from non-manual social class at birth had the lowest risk for IHD as adults. We conclude that low foetal growth rate rather than placental weight was more predictive of IHD in the Swedish cohort. However, the strong effect of social class at birth on risk for IHD did not appear to be mediated by foetal growth rate.


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