scholarly journals Influence of family factors on the incidence of lower respiratory illness during the first year of life.

1976 ◽  
Vol 30 (4) ◽  
pp. 203-212 ◽  
Author(s):  
S R Leeder ◽  
R Corkhill ◽  
L M Irwig ◽  
W W Holland ◽  
J R Colley
PEDIATRICS ◽  
1985 ◽  
Vol 75 (3) ◽  
pp. 594-597
Author(s):  
Frank A. Pedreira ◽  
Vincent L. Guandolo ◽  
Edward J. Feroli ◽  
Gordon W. Mella ◽  
Ira P. Weiss ◽  
...  

A prospective study of 1,144 infants and their families was performed. Smoking and family histories were evaluated with respect to the incidence of lower respiratory disease during the first year of life. It was found that (1) tracheitis and bronchitis occurred significantly more frequently in infants exposed to cigarette smoke in the home, (2) maternal smoking imposed greater risks upon the infant than paternal smoking, (3) occurrence of neither tracheitis nor bronchitis showed a consistent relationship to the number of cigarettes smoked, (4) a family history that was positive for respiratory illness (chronic cough or bronchitis) significantly influenced the incidence of bronchitis, (5) too few cases of laryngitis and pneumonia were seen to warrant any opinions regarding the adverse influence of either smoking or a family history that was positive for respiratory illness, and (6) occurrence of bronchiolitis was not affected by the presence of a smoker nor influenced by a family history that was positive for respiratory illness. It is concluded that passive smoking is dangerous to the health of infants and that infants born to families with a history that is positive for respiratory illness (chronic cough or bronchitis) are at risk of developing bronchitis.


BMJ ◽  
1986 ◽  
Vol 293 (6552) ◽  
pp. 925-927 ◽  
Author(s):  
C J Watkins ◽  
Y Sittampalam ◽  
J Bartholomew

1995 ◽  
Vol 20 (3) ◽  
pp. 137-144 ◽  
Author(s):  
Alan Adler ◽  
Ira B. Tager ◽  
Randall W. Brown ◽  
Long Ngo ◽  
John P. Hanrahan

2019 ◽  
Vol 53 (2) ◽  
pp. 1800998 ◽  
Author(s):  
Diane M. Gray ◽  
Dorottya Czovek ◽  
Lauren McMillan ◽  
Lidija Turkovic ◽  
Jacob A.M. Stadler ◽  
...  

Lower respiratory tract illness (LRTI) is a leading cause of mortality and morbidity in children. Sensitive and noninvasive infant lung function techniques are needed to measure risk for and impact of LRTI on lung health. The objective of this study was to investigate whether lung function derived from the intra-breath forced oscillation technique (FOT) was able to identify healthy infants at risk of LRTI in the first year of life.Lung function was measured with the novel intra-breath FOT, in 6-week-old infants in a South African birth cohort (Drakenstein Child Health Study). LRTI during the first year was confirmed by study staff. The association between baseline lung function and LRTI was assessed with logistic regression and odds ratios determined using optimal cut-off values.Of the 627 healthy infants with successful lung function testing, 161 (24%) had 238 LRTI episodes subsequently during the first year. Volume dependence of respiratory resistance (ΔR) and reactance (ΔX) was associated with LRTI. The predictive value was stronger if LRTI was recurrent (n=50 (31%): OR 2.5, ΔX), required hospitalisation (n=38 (16%): OR 5.4, ΔR) or was associated with wheeze (n=87 (37%): OR 3.9, ΔX).Intra-breath FOT can identify healthy infants at risk of developing LRTI, wheezing or severe illness in the first year of life.


Author(s):  
Kaharu C. Sumino ◽  
Cindy M. Visness ◽  
John Schwarz ◽  
Gordon R. Bloomberg ◽  
James E. Gern ◽  
...  

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